PIRFENOID 200

PIRFENOID 200 is a prescription tablet containing pirfenidone (200 mg), marketed in India by Steris Healthcare Pvt. Ltd.

Pirfenidone belongs to a class of medicines called antifibrotic (anti-scarring) agents. Its exact mechanism is not fully understood, but laboratory and clinical research shows it reduces the production of fibroblasts and collagen, the cells and proteins that form scar tissue, and dampens certain inflammatory signals involved in fibrosis. In simple terms, it helps slow the process that makes lung tissue thick and stiff.

Pirfenidone is approved for the treatment of mild to moderate idiopathic pulmonary fibrosis in adults. The 200 mg strength is commonly used for dose initiation and titration, since treatment typically starts low and is increased step by step to reduce stomach and other side effects.

Product Information 

Why Is Pirfenidone Important?

1. It slows the progression of IPF: IPF is a progressive disease. Clinical trials have shown that pirfenidone reduces the rate of decline in forced vital capacity (FVC), a key measure of how much air your lungs can hold, compared with placebo. Slower decline can mean more time with better breathing.

2. It helps preserve quality of life: Preserving lung function can mean continuing everyday activities, such as walking, household work and time with family, for longer.

3. It is a long-term therapy with long-term payoff: Pirfenidone does not give instant relief; the benefit comes from consistent use over months and years. Missing doses or stopping early reduces that benefit.

4. It fits into a complete care plan: IPF care also includes oxygen support when needed, pulmonary rehabilitation, vaccinations and managing reflux and other conditions. Pirfenidone is one important piece of that plan.

Key Benefits 

• Slows lung function decline: Helps reduce the yearly loss of FVC in IPF patients.
• Anti-scarring action: Targets the fibrotic process rather than only treating symptoms.
• Flexible dose titration: The 200 mg strength allows gradual dose build-up, which helps many patients tolerate treatment better.
• Oral tablet convenience: Taken by mouth, no injections or hospital visits needed for each dose.
• Taken with food: Helps reduce stomach upset.
• Studied in large clinical trials: Pirfenidone has been evaluated in multiple international studies and is recommended in IPF treatment guidelines.
• Supports long-term stability: Consistent therapy may help some patients stay stable for longer.

Precautions: What You Should Know Before Using It

Tell your doctor about your full medical history before starting pirfenidone.

Do not use if

• You are allergic to pirfenidone or any ingredient in the tablet.
• You have a history of angioedema (swelling of the face, lips, tongue or throat) with pirfenidone.
• You are taking fluvoxamine (an antidepressant), which strongly raises pirfenidone levels.
• You have severe liver impairment or end-stage kidney disease requiring dialysis.

Use with caution and medical supervision if

• You have mild to moderate liver problems. Liver function tests are required before starting and regularly during treatment.
• You have mild to moderate kidney impairment.
• You are pregnant, planning pregnancy or breastfeeding. Discuss risks and benefits with your doctor.
• You are elderly, as you may be more sensitive to side effects.
• You are a smoker. Smoking reduces pirfenidone levels in the blood and may weaken its effect. Quitting is strongly advised.
• You take medicines that affect the CYP1A2 enzyme, such as ciprofloxacin (an antibiotic), as dose adjustment may be required.

Possible Side Effects

Like all medicines, PIRFENOID 200 can cause side effects, though not everyone experiences them. Many are manageable and often improve with dose adjustment or by taking tablets with food.

Common side effects

• Nausea and vomiting
• Loss of appetite and weight loss
• Diarrhoea, indigestion or acid reflux
• Stomach pain or bloating
• Fatigue
• Dizziness
• Headache
• Sleep difficulty
• Skin rash or itching
• Sunburn-like reaction (photosensitivity)

Less common effects

• Joint pain
• Dry skin
• Taste changes
• Cough or breathlessness (note that these can also be IPF symptoms, so report any worsening)

Frequently Asked Questions

Where can I buy Pirfenidone 200 online?

Pirfenidone 200 can be purchased through licensed and authorized pharmacies or online medicine platforms, subject to prescription requirements and product availability.

What is the price of Pirfenidone 200?

The price may vary depending on the brand, strength, pack size, manufacturer, pharmacy, and applicable offers. Check the current listed price before ordering.

Can I order Pirfenidone 200 online?

Yes, Pirfenidone 200 may be ordered online through authorized pharmacies when a valid prescription and applicable purchasing requirements are fulfilled.

Is Pirfenidone 200 available from Steris Healthcare?

Availability depends on the current Steris Healthcare product range and stock. Check the relevant Steris Healthcare product listing or contact the company for current availability.

What is Pirfenidone 200 used for?

Pirfenidone is an antifibrotic medicine used to help treat idiopathic pulmonary fibrosis (IPF), a chronic lung condition that causes progressive scarring of lung tissue. It is used under the supervision of a healthcare professional.

What is the composition of Pirfenidone 200?

The active ingredient is Pirfenidone 200 mg. The inactive ingredients may vary depending on the manufacturer and formulation.

Is a prescription required?

Yes, Pirfenidone is a prescription medicine and should be used only under the supervision of a qualified healthcare professional.

How should Pirfenidone 200 be taken?

Take Pirfenidone 200 exactly as prescribed by your doctor. It is generally taken orally with food to help reduce stomach-related side effects. Swallow the tablet with water and do not change the dose or stop treatment without medical advice.

What should I know before buying Pirfenidone 200?

Check the strength, formulation, pack size, manufacturer, expiry date, and authenticity before purchasing. Inform your doctor about liver or kidney problems, other medicines or supplements you take, and any history of sensitivity to sunlight. Regular medical monitoring may be required during treatment.

How can I order Pirfenidone 200 online?

Choose a licensed online pharmacy, verify the product details and current price, provide a valid prescription, and complete the pharmacy's ordering and payment process. Use Pirfenidone only according to your doctor's instructions.