Alfacalcidol (0.25mcg)

Alfacalcidol capsules

Alfacalcidol capsules 0.25 mcg uses include the prevention and treatment of calcium and vitamin D deficiencies that lead to conditions such as osteoporosis, rickets, and renal bone disease. FABRICAL ALPHA 0.25, developed by Steris Healthcare, is a high-quality formulation of alfacalcidol soft gelatin capsules 0.25 mcg, designed to restore proper bone mineralization and calcium balance in patients with kidney and bone disorders.

This supplement is commonly prescribed by healthcare providers in cases of chronic kidney disease (CKD), hypoparathyroidism, and other metabolic bone diseases, where the body’s ability to convert vitamin D to its active form is compromised.

What is FABRICAL ALPHA 0.25?

FABRICAL ALPHA 0.25 is a soft gelatin capsule containing alfacalcidol 0.25 mcg, a synthetic analog of vitamin D that gets converted in the liver to calcitriol, the active form of vitamin D3. This activated form plays a crucial role in calcium absorption and bone mineralization, helping prevent skeletal deformities, weak bones, and calcium imbalance in the blood.

Unlike regular vitamin D3 supplements that rely on kidney function for activation, alfacalcidol bypasses this step and is effective even in patients with renal impairment.

Alfacalcidol Capsules 0.25 mcg Uses

Understanding alfacalcidol capsules 0.25 mcg uses is essential for those at risk of vitamin D-related complications. The key uses include:

• Chronic Kidney Disease (CKD): In CKD, the kidneys lose their ability to activate vitamin D. FABRICAL ALPHA 0.25 helps correct the vitamin D deficiency and regulates parathyroid hormone (PTH) levels.

• Hypoparathyroidism: It helps in maintaining calcium homeostasis when the parathyroid glands fail to function.

• Rickets and Osteomalacia: These conditions cause bone softening due to vitamin D deficiency. Alfacalcidol promotes bone growth and mineralization.

• Osteoporosis (especially postmenopausal): Enhances calcium absorption and strengthens bones in elderly and menopausal women.

• Renal Osteodystrophy: A condition common in dialysis patients, characterized by bone pain and deformities.

How FABRICAL ALPHA 0.25 Works

Alfacalcidol is converted in the liver to calcitriol, which then acts on the intestines to increase calcium and phosphate absorption. It also reduces PTH secretion from the parathyroid glands and stimulates proper mineralization of bones.

Because alfacalcidol does not depend on kidney hydroxylation (unlike cholecalciferol), it is especially useful for patients with renal disorders.

Dosage & Administration

FABRICAL ALPHA 0.25 should be taken orally with or after meals, ideally under medical supervision. The typical dosage varies from 0.25 mcg to 1 mcg per day, depending on the patient’s age, condition, and response to treatment.

• Note: Overdosage may lead to hypercalcemia (high calcium levels), so blood calcium levels should be regularly monitored during long-term use.

Side Effects of Alfacalcidol Capsules

While alfacalcidol capsules are generally well tolerated, some patients may experience:

• Hypercalcemia (symptoms: nausea, vomiting, weakness, confusion)

• Headache or dizziness

• Constipation or abdominal discomfort

• Increased thirst and urination

Severe side effects are rare but should be immediately reported to a doctor.

Precautions Before Use

• Inform your doctor if you have heart disease, kidney stones, or liver dysfunction.

• Avoid simultaneous use of high-dose calcium supplements unless advised.

• Regular blood tests (serum calcium, phosphate, and PTH levels) are important.

• Use cautiously during pregnancy and breastfeeding.

Drug Interactions

• Diuretics (like thiazides) may increase the risk of hypercalcemia.

• Magnesium-containing antacids may cause toxicity.

• Digitalis toxicity can worsen with high calcium levels.

• Phosphate binders and corticosteroids may reduce effectiveness.

Always consult a physician before starting alfacalcidol capsules, especially if you're on long-term medication.

Storage Instructions

Store below 25°C in a dry, cool place. Protect from sunlight and moisture. Keep out of reach of children.

Why Choose FABRICAL ALPHA 0.25 by Steris Healthcare?

Steris Healthcare is one of India’s most trusted pharmaceutical brands, known for its WHO-GMP certified manufacturing units, stringent quality controls, and ethical practices. FABRICAL ALPHA 0.25 is a product of precision formulation and clinical validation, offering:

• Superior bioavailability

• Reliable therapeutic outcomes

• Affordable pricing

• Safe packaging for long shelf-life

• Nationwide availability via medical stores and SterisOnline.com

With Steris Healthcare, patients and doctors alike benefit from consistency, affordability, and safety — a combination that’s hard to beat.

Frequently Asked Questions (FAQs)

Q1. What are alfacalcidol capsules 0.25 mcg uses?
Alfacalcidol is used to treat conditions like chronic kidney disease, hypoparathyroidism, osteoporosis, rickets, and osteomalacia by improving calcium and vitamin D3 levels in the body.

Q2. What is the difference between alfacalcidol and cholecalciferol?
Cholecalciferol (vitamin D3) requires kidney activation, while alfacalcidol is already active and only requires liver conversion, making it more suitable for kidney patients.

Q3. Is alfacalcidol safe during pregnancy?
It should only be used if prescribed by a doctor, as excess calcium may harm the fetus.

Q4. Can alfacalcidol capsules be taken with calcium supplements?
Yes, but under medical supervision, as the risk of hypercalcemia increases when combined.

Q5. How long should I take FABRICAL ALPHA 0.25?
The duration depends on your medical condition and blood test results. Follow your doctor's advice strictly.

Conclusion

FABRICAL ALPHA 0.25 is an advanced solution for vitamin D-related deficiencies, especially in patients suffering from kidney dysfunction, bone loss, or hormonal imbalances. It improves calcium metabolism, strengthens bones, and restores mineral balance efficiently.

With the trusted name of Steris Healthcare backing it, this formulation of alfacalcidol soft gelatin capsules 0.25 mcg offers both safety and reliability. Whether you’re managing CKD or preventing osteoporosis, knowing the full scope of alfacalcidol capsules 0.25 mcg uses is the first step towards better bone health and overall well-being.