Ambrisentan (5mg) & AMBRISTAR 5 Mg : Uses, Dosage, Side Effects, Precaution and More.

AMBRISTAR 5 Mg

Ambrisentan (5mg)

Ambrisentan, marketed under the brand name AMBRISTAR 5 mg, is a prescription medication primarily used in the management of pulmonary arterial hypertension (PAH). This medication belongs to a class of drugs known as endothelin receptor antagonists, which work by blocking the action of endothelin, a substance in the body that causes blood vessels to constrict. By inhibiting this action, ambrisentan helps to lower blood pressure in the lungs, improve exercise capacity, and delay the progression of PAH.

Uses

Ambrisentan is specifically indicated for the treatment of PAH (WHO Group 1) in adults. Its primary therapeutic goals include:

• Reducing Symptoms: It alleviates symptoms such as shortness of breath, fatigue, and chest pain associated with PAH.
• Improving Exercise Capacity: By decreasing pulmonary blood pressure, it enhances the ability to perform physical activities.
• Slowing Disease Progression: Ambrisentan has been shown to delay clinical worsening, thus improving the quality of life for PAH patients.

Dosage

The typical dosage for ambrisentan is as follows:

• Starting Dose: The recommended starting dose is 5 mg taken once daily, with or without food.
• Maintenance Dose: Depending on the patient's response and tolerance, the dose may be increased to 10 mg once daily.
• Administration: It is essential to take ambrisentan at the same time each day to maintain an even level of the drug in the bloodstream. Do not split, crush, or chew the tablets.

Side Effects

Like any medication, ambrisentan may cause side effects. Common side effects include:

• Peripheral Edema: Swelling of the legs, ankles, or feet is the most frequently reported side effect.
• Nasal Congestion: Patients may experience a stuffy or runny nose.
• Flushing: Some individuals report a warm or red feeling in the face and neck.
• Headache: Mild to moderate headaches can occur.
• Anemia: A reduction in red blood cell count, which may lead to fatigue and weakness.

More serious side effects, though less common, include liver injury, low blood pressure, and potential teratogenic effects. It is crucial to monitor liver function regularly and to avoid pregnancy while on this medication.

Price

The cost of ambrisentan can vary significantly depending on the pharmacy, location, and whether the patient has insurance coverage. On average, the price for a 30-day supply of AMBRISTAR 5 mg can range from $1,000 to $3,000. Patients are advised to check with their healthcare provider or insurance company for specific pricing and potential financial assistance programs.

More Information

• Monitoring: Regular monitoring of liver enzymes and hemoglobin levels is recommended during treatment.
• Interactions: Ambrisentan can interact with other medications, including certain antifungals, antibiotics, and other drugs used to treat PAH. Inform your doctor about all medications and supplements you are taking.
• Pregnancy and Breastfeeding: Ambrisentan is contraindicated during pregnancy due to the risk of birth defects. Breastfeeding while taking ambrisentan is not recommended.

Conclusion

Ambrisentan (AMBRISTAR 5 mg) is a vital medication for managing pulmonary arterial hypertension, offering significant benefits in symptom relief, exercise capacity, and disease progression. Patients must adhere to prescribed dosages, be aware of potential side effects, and undergo regular monitoring to ensure the best possible outcomes. Always consult your healthcare provider for personalized advice and information about this medication. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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