Amlodipine 5mg + Bisoprolol 5mg (BISOGARD AM)-: Uses, Benefits, Side Effects, Dosage & More ......

Introduction

BISOGARD AM is a fixed-dose combination tablet containing Amlodipine 5 mg, a calcium channel blocker (CCB), and Bisoprolol 5 mg, a beta-1 selective blocker. This combination is formulated for effective management of hypertension (high blood pressure), angina pectoris, and prevention of cardiovascular complications. BISOGARD AM offers a powerful dual mechanism of action that targets both vascular smooth muscles and the heart, making it a superior choice in modern antihypertensive therapy.

Composition of BISOGARD AM

Each film-coated tablet contains:

• Amlodipine Besylate equivalent to Amlodipine – 5 mg

• Bisoprolol Fumarate equivalent to Bisoprolol – 5 mg

Dosage Form: Oral tablet
Packaging: Blister pack of 10 tablets

What is Amlodipine 5 mg?

Amlodipine is a dihydropyridine calcium channel blocker that works by relaxing arterial walls and reducing vascular resistance. It improves blood flow and reduces the heart’s workload.

Amlodipine 5 mg Tablet Uses

• Hypertension (High Blood Pressure)

• Chronic Stable Angina

• Vasospastic (Prinzmetal’s) Angina

• Prevention of stroke and heart attack in hypertensive patients

Amlodipine 5 mg Uses in Hindi (एम्लोडिपिन 5 मि.ग्रा. के उपयोग)

• उच्च रक्तचाप को नियंत्रित करने के लिए

• सीने में दर्द (एंजाइना) से राहत पाने में

• स्ट्रोक और दिल की बीमारी की रोकथाम के लिए

What is Bisoprolol 5 mg?

Bisoprolol is a beta-1 selective adrenergic blocker that slows the heart rate and reduces myocardial oxygen demand. It’s especially effective in patients with coexisting heart failure, arrhythmias, or post-myocardial infarction.

Bisoprolol 5 mg Uses

• Hypertension

• Chronic Stable Angina

• Congestive Heart Failure (CHF)

• Irregular heartbeats

• Heart protection post-heart attack

Bisoprolol 5 mg Uses in Hindi (बिसोप्रोलोल 5 मि.ग्रा. के उपयोग)

• रक्तचाप को कम करने में

• दिल की विफलता (Heart Failure) में

• दिल की धड़कन को सामान्य करने में

• एंजाइना और हार्ट अटैक की रोकथाम में

Uses of BISOGARD AM Tablet

• Essential Hypertension

• Angina Pectoris (Chronic stable & variant)

• Patients with hypertension and coexisting heart conditions

• Cardiovascular risk reduction in high-risk hypertensive individuals

How BISOGARD AM Works

Amlodipine:

• Inhibits calcium ion influx into vascular smooth muscles.

• Dilates arteries and lowers peripheral resistance.

• Reduces afterload, improving cardiac efficiency.

Bisoprolol:

• Blocks beta-1 receptors in the heart.

• Reduces heart rate and myocardial contractility.

• Decreases cardiac workload and oxygen consumption.

Together, these ingredients work synergistically to lower blood pressure and prevent heart strain and complications.

Dosage and Administration

• Recommended Dose: One tablet once daily, preferably in the morning.

• May be taken with or without food.

• Dosage adjustments may be made based on patient’s response and tolerability.

Best Time to Take Amlodipine 5 mg

Morning is ideal to maintain 24-hour blood pressure control and prevent early-morning cardiovascular events.

Side Effects of BISOGARD AM

Common Side Effects

• Dizziness or fatigue

• Slow heartbeat (bradycardia)

• Swelling of feet or ankles (edema)

• Headache

• Cold extremities

Serious Side Effects (Rare)

• Hypotension

• Shortness of breath or wheezing

• Worsening of heart failure symptoms

• Allergic reactions (rash, swelling)

Precautions and Warnings

• Use cautiously in patients with severe liver or kidney impairment.

• Avoid abrupt discontinuation, especially in ischemic heart disease.

• Monitor pulse regularly in patients on bisoprolol.

• Not recommended in pregnancy or lactation unless prescribed.

• May mask symptoms of hypoglycemia in diabetic patients.

Drug Interactions

Drugs That May Interact

• Other antihypertensives (additive effect)

• NSAIDs (may reduce effectiveness of amlodipine)

• Digoxin and anti-arrhythmic drugs (increased risk of bradycardia)

• CYP3A4 inhibitors (e.g., ketoconazole may raise amlodipine levels)

• Insulin or oral antidiabetics (bisoprolol may mask hypoglycemia symptoms)

Storage Instructions

• Store in a cool, dry place below 25°C.

• Protect from direct sunlight and moisture.

• Keep out of reach of children.

Why Choose BISOGARD AM by Steris Healthcare?

• WHO-GMP Certified Manufacturing

• High-quality, cost-effective formulation

• Precision in dosing with once-daily convenience

• Trusted brand with nationwide distribution

Steris Healthcare Pvt Ltd delivers reliability, quality, and efficacy in every tablet. BISOGARD AM exemplifies their commitment to cardiovascular wellness.

Frequently Asked Questions (FAQs)

Q1. Can BISOGARD AM be taken long-term?

Yes, it’s suitable for long-term management of blood pressure under medical supervision.

Q2. Can I stop taking BISOGARD AM if I feel better?

No. Hypertension is a chronic condition; stopping the medicine suddenly can worsen your health. Consult your doctor first.

Q3. Does BISOGARD AM cause drowsiness?

Some patients may feel lightheaded or tired initially. It usually subsides with time.

Q4. What if I miss a dose?

Take the missed dose as soon as you remember. Skip if it's close to the next dose. Do not double up.

Conclusion

BISOGARD AM is a clinically effective and well-tolerated fixed-dose combination of Amlodipine 5 mg and Bisoprolol 5 mg, formulated to deliver dual protection against high blood pressure and cardiovascular stress. With proven safety, once-daily dosing, and powerful results, BISOGARD AM is ideal for patients needing a multi-targeted approach to blood pressure and heart health.