Aspirin Gastro Resistant 75mg: Complete Guide to Uses, Benefits & Precautions

Introduction

Aspirin Gastro Resistant 75mg (commonly known under brands like ST SPRIN 75 ) is a specialized low-dose formulation designed to maximize cardiovascular benefits while minimizing gastrointestinal side effects. This guide covers all medically relevant aspects, including uses, precautions, pregnancy considerations, mechanism of action, side effects, composition, and patient FAQs.

What is Aspirin Gastro Resistant 75mg?

Each tablet contains 75mg aspirin (acetylsalicylic acid) as the active ingredient, formulated with a Gastro Resistant coating that resists dissolving in the stomach and instead releases the drug in the intestine. This design helps reduce stomach irritation, ulcers, and bleeding—common concerns with regular aspirin. Common brand examples include ST SPRIN 75.

Composition of Aspirin Gastro Resistant 75mg Tablets

• Active Ingredient: Aspirin (acetylsalicylic acid) 75mg

• Inactive Ingredients (Excipients): Typically include microcrystalline cellulose, lactose, corn starch, colloidal silica, stearic acid, and others—exact composition may vary by brand.

• Lactose/Sucrose Content: Some formulations contain small amounts of lactose or sucrose; inform your doctor if you have intolerances.

Brand Names and Availability

Aspirin Gastro Resistant 75mg is available under various brand names in different countries, including:

• ST SPRIN 75 (Steris Healthcare)

Prescription Required: This medication is usually prescription-only. Do not start or stop aspirin without consulting your healthcare provider.

Uses of Aspirin Gastro Resistant 75mg

• Cardiovascular Protection: Primarily prescribed to prevent blood clots—thereby reducing the risk of heart attacks, strokes (especially ischemic strokes), and angina (chest pain due to reduced blood flow to the heart).

• Secondary Prevention: Used in patients who have a history of cardiovascular events (like previous heart attack or stroke) or those at high risk due to diabetes, hypertension, or high cholesterol.

• Post-Surgical Care: May be recommended after certain heart surgeries (such as bypass or angioplasty) to prevent clot formation during recovery.

• Other Uses: High-dose aspirin is used for pain, fever, and inflammation, but the 75mg dose is specifically for antiplatelet (clot-preventing) effects and is not generally used for pain relief.

Aspirin Gastro Resistant 75mg in Pregnancy

• Low-dose aspirin (75–150mg/day) is sometimes prescribed during pregnancy to prevent pre-eclampsia (a serious complication marked by high blood pressure and organ damage) in women at high risk. It is typically started at 12 weeks of gestation and continued until delivery.

• Other Indications: May be used in women with a history of recurrent miscarriage, fetal growth restriction, or previous preterm birth, as well as those undergoing fertility treatments such as IVF.

• Safety: Low-dose aspirin is generally considered safe during pregnancy when prescribed by a healthcare provider, but should not be used without medical supervision. High doses, especially in the third trimester, can harm the unborn baby and should be avoided.

• Do not self-medicate during pregnancy—always consult your obstetrician before starting or stopping aspirin.

How Does Aspirin Gastro Resistant 75mg Work?

Aspirin inhibits the cyclooxygenase (COX) enzyme, reducing the production of thromboxane A2—a substance that promotes platelet clumping and blood clot formation. By preventing platelet aggregation, aspirin helps maintain blood flow in arteries, reducing the risk of clot-related events like heart attack and stroke.
The Gastro Resistant coating ensures the drug is absorbed in the intestine, protecting the stomach lining from irritation.

Dosage and Administration

• Standard Dose: Usually one 75mg tablet daily, swallowed whole with water—do not crush, chew, or break the tablet to preserve the Gastro Resistant coating.

• Timing: Can be taken with or without food, though taking it with food may help minimize stomach upset.

• Missed Dose: If you forget a dose, take it as soon as you remember. Do not double the dose to make up for a missed one.

• Always follow your doctor’s instructions regarding dose and duration.

Side Effects and Precautions

Common Side Effects:

• Increased bleeding tendency (e.g., easier bruising, longer bleeding from cuts)

• Indigestion, mild stomach discomfort

• Rarely: Allergic reactions (rash, swelling, difficulty breathing), severe bleeding (blood in vomit, urine, or stools), or liver problems

When to Seek Immediate Medical Attention:

• Unusual bleeding (nosebleeds, bleeding gums, blood in vomit or stools)

• Severe stomach pain, black/tarry stools, coughing up blood

• Signs of allergic reaction (swelling, rash, difficulty breathing)

Precautions:

• Avoid if you have a history of ulcers, bleeding disorders, or severe kidney/liver disease.

• Use with caution if you have asthma, gout, or are taking other blood-thinning medications.

• Do not give to children under 16 due to the risk of Reye’s syndrome.

• Inform your doctor about all medications and supplements you are taking.

Patient FAQs

Q: Can I take Aspirin Gastro Resistant 75mg for pain or fever?
A: No. The 75mg dose is for cardiovascular protection, not pain or fever relief.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, but do not double the next dose.

Q: Can I drink alcohol while taking this medicine?
A: Alcohol may increase the risk of stomach bleeding. Limit alcohol intake and discuss with your doctor.

Q: How long do I need to take this medicine?
A: Duration depends on your condition. Do not stop without consulting your doctor, as sudden discontinuation may increase the risk of heart attack or stroke.

Q: Are there any dietary restrictions?
A: No specific restrictions, but maintain a heart-healthy diet. Inform your doctor if you have lactose intolerance.

Q: What should I do if I experience side effects?
A: Contact your doctor immediately if you notice unusual bleeding, severe stomach pain, or allergic reactions.

Key Takeaways

• Aspirin Gastro Resistant 75mg is a low-dose, enteric-coated aspirin used primarily to prevent heart attacks, strokes, and blood clots in at-risk individuals.

• In pregnancy, it may be prescribed to prevent pre-eclampsia and other complications in high-risk women, but must only be used under medical supervision.

• The Gastro Resistant coating reduces stomach irritation, making it suitable for long-term use in many patients.

• Side effects are generally mild but can include bleeding and indigestion. Serious side effects require immediate medical attention.

• Always follow your doctor’s instructions and report any concerns promptly.

When to Consult Your Doctor

• Before starting aspirin, especially if you are pregnant, planning pregnancy, or breastfeeding.

• If you experience any side effects or have concerns about interactions with other medications.

• For any changes in your health status that might affect the safety or effectiveness of this medication.

Aspirin Gastro Resistant 75mg is a cornerstone of cardiovascular prevention, but its use must be personalized and monitored by a healthcare professional to ensure safety and efficacy.

Conclusion

Aspirin Gastro-Resistant 75mg (such as ST SPRIN 75 by Steris Healthcare Pvt Ltd) is a reliable medication for long-term cardiovascular protection, offering reduced stomach irritation thanks to its gastro-resistant coating. Steris Healthcare is a trusted manufacturer, known for strict quality standards, regulatory compliance, and a patient-focused approach—ensuring you receive safe, effective, and affordable medicines. Always consult your doctor before starting this medication.