CAPECITIME 500 & Capecitabine lp (500mg. available upto 30% Discount….

CAPECITIME 500

Capecitabine lp (500mg)

CAPECITIME 500 is a pharmaceutical product containing Capecitabine lp (500mg), an oral chemotherapy medication used in the treatment of various cancers. Capecitabine is a prodrug that is converted into 5-fluorouracil (5-FU) in the body, a compound that interferes with the growth and spread of cancer cells. This medication is particularly effective in treating colorectal, breast, and gastric cancers.

Uses of CAPECITIME 500

Treatment of Colorectal Cancer

• Adjuvant Therapy: CAPECITIME 500 is used as adjuvant therapy in patients with stage III colon cancer after surgery to reduce the risk of cancer recurrence.
• Metastatic Colorectal Cancer: It is also prescribed for the treatment of metastatic colorectal cancer, either as monotherapy or in combination with other chemotherapeutic agents.

Treatment of Breast Cancer

• Metastatic Breast Cancer: CAPECITIME 500 is used in patients with metastatic breast cancer, particularly those who have not responded to other treatments like anthracycline and taxane-based therapies.
• Combination Therapy: It can be combined with other medications such as docetaxel to enhance its effectiveness.

Treatment of Gastric Cancer

• Advanced Gastric Cancer: CAPECITIME 500 is used in the treatment of advanced gastric cancer, often in combination with platinum-based chemotherapy agents like cisplatin.

Mechanism of Action

• Prodrug Activation: Capecitabine is converted into 5-fluorouracil (5-FU) in the body, primarily in tumor tissues. This selective activation minimizes systemic toxicity.
• Inhibition of DNA Synthesis: 5-FU interferes with the synthesis of DNA and RNA in cancer cells, inhibiting their growth and proliferation, and ultimately leading to cell death.

Dosage and Administration

Recommended Dosage

• The dosage of CAPECITIME 500 varies based on the type of cancer being treated, the patient's weight, and their overall health. It is typically administered in cycles, with a period of treatment followed by a rest period.
• For colorectal and gastric cancer, a common regimen involves taking CAPECITIME 500 twice daily for two weeks, followed by a one-week rest period. This cycle is repeated as necessary.
• For breast cancer, the dosage and schedule may vary depending on whether it is used as monotherapy or in combination with other treatments.

Administration Guidelines

• With Food: CAPECITIME 500 should be taken within 30 minutes after a meal to improve absorption and reduce gastrointestinal side effects.
• Swallow Whole: The tablets should be swallowed whole with water and not crushed or chewed.
• Regular Monitoring: Patients should have regular blood tests to monitor their blood cell counts, liver function, and kidney function.

Side Effects

Common Side Effects

• Gastrointestinal Issues: Diarrhea, nausea, vomiting, and abdominal pain are common side effects.
• Hand-Foot Syndrome: Patients may experience redness, swelling, and pain on the palms of the hands and the soles of the feet.
• Fatigue: Feeling tired or weak is frequently reported by patients taking CAPECITIME 500.
• Loss of Appetite: Some patients may experience a decreased appetite and weight loss.

Serious Side Effects

• Hematologic Toxicity: CAPECITIME 500 can cause bone marrow suppression, leading to low levels of white blood cells, red blood cells, and platelets. Regular blood tests are essential to monitor this.
• Cardiotoxicity: Rarely, CAPECITIME 500 can cause heart problems, including chest pain, arrhythmias, and heart attacks.
• Severe Diarrhea: Persistent or severe diarrhea can lead to dehydration and may require medical intervention.

Precautions and Warnings

Contraindications

• Allergy to Capecitabine: Patients with a known allergy to Capecitabine or 5-fluorouracil should not take this medication.
• Severe Renal Impairment: CAPECITIME 500 is contraindicated in patients with severe renal impairment due to the risk of increased toxicity.

Precautions

• Pregnancy and Breastfeeding: CAPECITIME 500 can harm an unborn baby and should not be used during pregnancy. Breastfeeding mothers should avoid this medication.
• Concurrent Medications: Patients should inform their healthcare provider about all medications they are taking, as CAPECITIME 500 can interact with other drugs.

Drug Interactions

Medications to Avoid

• Warfarin: Capecitabine can increase the effects of warfarin, a blood thinner, necessitating close monitoring of blood clotting parameters.
• Phenytoin: Co-administration with phenytoin can increase phenytoin levels, leading to toxicity.

Monitoring Required

• Other Chemotherapeutic Agents: When used with other chemotherapy drugs, careful monitoring is required to manage combined toxicities.

Patient Management

Lifestyle Modifications

• Dietary Considerations: Patients should maintain a balanced diet to support overall health and manage side effects like nausea and loss of appetite.
• Hydration: It is crucial to stay well-hydrated, especially if experiencing diarrhea.
• Hand-Foot Syndrome Management: Patients should avoid activities that put excessive pressure on the hands and feet, and use moisturizers to manage symptoms.

Regular Follow-Ups

• Blood Tests: Frequent blood tests are necessary to monitor blood cell counts, liver function, and kidney function.
• Physical Examinations: Routine check-ups with a healthcare provider help detect any potential side effects early and adjust treatment as needed.

Conclusion

CAPECITIME 500 is a vital medication in the treatment of various cancers, including colorectal, breast, and gastric cancers. Its mechanism of action as a prodrug that converts to 5-fluorouracil allows it to effectively target cancer cells while minimizing systemic toxicity. While there are potential side effects and precautions to consider, regular monitoring and adherence to prescribed dosages can help manage these risks. Patients taking CAPECITIME 500 should maintain open communication with their healthcare providers to ensure optimal treatment outcomes and address any concerns promptly. Understanding the uses, side effects, and precautions associated with CAPECITIME 500 allows patients to manage their condition more effectively and improve their quality of life. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

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