CARBIZOLE 10. - :Tablet- View Uses, Side Effects, Dosage, Mechanism of action...

CARBIZOLE 10

Caibimazole (10mg)

CARBIZOLE 10 is a pharmaceutical product containing Carvedilol (10mg), a medication used primarily to manage high blood pressure (hypertension) and heart failure. Carvedilol is a non-selective beta-blocker with alpha-blocking properties, which makes it effective in lowering blood pressure, reducing heart strain, and improving heart function. This guide will cover all important aspects of CARBIZOLE 10, including its uses, dosage, side effects, and precautions.

Uses of CARBIZOLE 10

Management of Hypertension

• Blood Pressure Control: CARBIZOLE 10 is used to help control high blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.
• Combination Therapy: It can be used alone or in combination with other antihypertensive medications to achieve optimal blood pressure control.

Treatment of Heart Failure

• Heart Function Improvement: CARBIZOLE 10 is used in patients with mild to severe chronic heart failure. It helps improve heart function and reduces symptoms such as shortness of breath and fatigue.
• Post-Heart Attack Management: It is also prescribed to improve survival rates and reduce the risk of further heart complications in patients who have experienced a heart attack.

Prevention of Angina

• Chest Pain Relief: By reducing the heart’s workload and improving oxygen supply to the heart, CARBIZOLE 10 can help prevent angina (chest pain) and improve exercise tolerance in patients with coronary artery disease.

Mechanism of Action

• Beta-Blockade: Carvedilol blocks beta-adrenergic receptors, reducing the effects of adrenaline and noradrenaline. This action slows the heart rate and lowers blood pressure.
• Alpha-Blockade: It also blocks alpha-adrenergic receptors, which helps to relax blood vessels and improve blood flow.
• Antioxidant Properties: Carvedilol has antioxidant effects, protecting the heart from oxidative stress and inflammation.

Dosage and Administration

Recommended Dosage

• The typical starting dose of CARBIZOLE 10 is 10mg taken once or twice daily, depending on the patient's condition and response. The dose may be gradually increased based on the patient’s response and tolerance.

Administration Guidelines

• Consistency: Take CARBIZOLE 10 at the same time each day to maintain even levels of the medication in your bloodstream.
• With Food: It is recommended to take CARBIZOLE 10 with food to reduce the risk of orthostatic hypotension (a sudden drop in blood pressure when standing up).
• Regular Monitoring: Patients should have their blood pressure, heart rate, and overall heart function regularly monitored to evaluate the effectiveness of the medication and adjust the dosage if necessary, under the guidance of a healthcare provider.

Side Effects

Common Side Effects

• Dizziness and Fatigue: Many patients experience dizziness and fatigue, especially when first starting the medication or after a dose increase.
• Bradycardia: A slow heart rate (bradycardia) can occur, causing symptoms such as lightheadedness and fatigue.
• Hypotension: Low blood pressure can lead to symptoms like dizziness, particularly when standing up quickly.

Serious Side Effects

• Heart Failure Worsening: In some cases, symptoms of heart failure may temporarily worsen. Patients should inform their healthcare provider if they experience increased shortness of breath, swelling of the ankles or feet, or sudden weight gain.
• Bronchospasm: CARBIZOLE 10 can cause bronchospasm, particularly in patients with a history of asthma or chronic obstructive pulmonary disease (COPD).
• Severe Bradycardia: A dangerously slow heart rate may occur, requiring immediate medical attention.

Precautions and Warnings

Contraindications

• Severe Bradycardia: Patients with severe bradycardia should not take CARBIZOLE 10.
• Asthma: CARBIZOLE 10 is contraindicated in patients with a history of asthma or severe chronic obstructive pulmonary disease (COPD) due to the risk of bronchospasm.
• Severe Liver Impairment: Patients with severe liver impairment should avoid CARBIZOLE 10 as the medication is metabolized in the liver.

Precautions

• Diabetes: CARBIZOLE 10 can mask symptoms of low blood sugar (hypoglycemia) in diabetic patients. Blood glucose levels should be monitored closely.
• Thyroid Disorders: The medication can mask symptoms of hyperthyroidism (overactive thyroid), such as a rapid heart rate. Sudden withdrawal of CARBIZOLE 10 can exacerbate hyperthyroidism.

Drug Interactions

Medications to Avoid

• Other Beta-Blockers: Combining CARBIZOLE 10 with other beta-blockers can increase the risk of severe bradycardia and hypotension.
• Calcium Channel Blockers: Co-administration with certain calcium channel blockers (e.g., verapamil, diltiazem) can increase the risk of heart block and severe bradycardia.
• CYP2D6 Inhibitors: Medications that inhibit the CYP2D6 enzyme (e.g., fluoxetine, paroxetine) can increase the blood levels of carvedilol, leading to increased side effects.

Monitoring Required

• Blood Pressure and Heart Rate: Regular monitoring of blood pressure and heart rate is essential to ensure that CARBIZOLE 10 is working effectively and to adjust dosages as needed.
• Liver Function Tests: Periodic liver function tests may be necessary to monitor for potential liver-related side effects.

Patient Management

Lifestyle Modifications

• Dietary Considerations: Patients should follow a heart-healthy diet, low in salt and saturated fats, to support overall cardiovascular health and enhance the effectiveness of CARBIZOLE 10.
• Exercise: Regular physical activity, as recommended by a healthcare provider, can help improve heart function and overall health. Patients should avoid sudden intense exercise without medical advice.
• Smoking Cessation: Quitting smoking can improve cardiovascular health and reduce the risk of complications.

Regular Follow-Ups

• Medical Appointments: Regular check-ups with a healthcare provider are crucial to monitor the effectiveness of CARBIZOLE 10 and adjust the treatment plan as necessary.
• Blood Tests: Periodic blood tests, including liver function tests and blood glucose levels (for diabetic patients), are essential to monitor the patient's response to the medication and detect any potential side effects early.

Conclusion

CARBIZOLE 10 is a valuable medication in the management of hypertension and heart failure. By effectively reducing blood pressure and improving heart function, it provides significant therapeutic benefits to patients. While there are potential side effects and precautions to consider, regular monitoring and adherence to prescribed dosages can help manage these risks. Patients taking CARBIZOLE 10 should maintain open communication with their healthcare providers to ensure optimal treatment outcomes and address any concerns promptly. Understanding the uses, side effects, and precautions associated with CARBIZOLE 10 allows patients to manage their condition more effectively and improve their quality of life. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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