Carvedilol and Ivabradine Tablets: View Uses, Benefits, Dosage, Price, Side Effects.

Carvedilol and Ivabradine Tablets are a fixed-dose combination medicine widely prescribed for the management of certain heart conditions, particularly chronic heart failure and angina (chest pain due to reduced blood flow to the heart). By combining Carvedilol, a beta-blocker, and Ivabradine, a heart rate-lowering agent, this formulation offers a dual approach to improving heart function, reducing symptoms, and enhancing overall quality of life. 

In this article, we will explore Carvedilol and Ivabradine Tablets in detail, covering their uses, benefits, dosage guidelines, price information, and potential side effects. We will also answer common questions to help patients better understand this medication. 

What are Carvedilol and Ivabradine Tablets?

The Carvedilol+Ivabradine combination brings together two different classes of cardiovascular medicines:

• Carvedilol: A non-selective beta-blocker with alpha-blocking activity. It helps lower blood pressure, reduce heart rate, and decrease the workload on the heart.

• Ivabradine: A selective sinus node inhibitor. It works by slowing the heart rate without affecting blood pressure, improving oxygen supply to the heart muscle.

Together, Carvedilol and Ivabradine are used to manage heart failure and angina, particularly in patients who need additional heart rate control beyond what beta-blockers alone can provide.

Uses of Carvedilol and Ivabradine Tablets

The main uses of Carvedilol and Ivabradine Tablets include:

1. Chronic Heart Failure (CHF) – Helps improve heart efficiency and reduce symptoms like fatigue, shortness of breath, and fluid retention.

2. Stable Angina Pectoris – Reduces frequency and severity of chest pain by lowering heart rate and improving oxygen delivery to heart tissues.

3. Post-Heart Attack Care – May be used as part of long-term therapy to reduce the risk of further cardiac events.

4. Heart Rate Management – For patients whose heart rate remains high despite optimal beta-blocker therapy.  

Benefits of Carvedilol and Ivabradine Tablets

This fixed-dose combination offers several benefits:

• Dual Action: Targets heart rate and blood pressure simultaneously for better symptom control.

• Improved Heart Function: Helps the heart pump more efficiently in patients with weakened heart muscles.

• Reduced Hospitalizations: Studies show fewer heart failure-related hospital visits with appropriate use.

• Better Exercise Tolerance: Patients can often perform daily activities with reduced fatigue.

• Convenience: Combination tablet reduces pill burden compared to taking two separate medicines. 

How Do Carvedilol and Ivabradine Work?

• Carvedilol blocks beta-1 and beta-2 adrenergic receptors and alpha-1 receptors. This relaxes blood vessels, reduces heart rate, and lowers blood pressure.

• Ivabradine specifically inhibits the “funny” current (If) in the sinoatrial node, slowing heart rate without lowering blood pressure significantly.

The result is improved oxygen balance in the heart, reduced strain, and better overall cardiovascular performance. 

Dosage & Administration

Important: Dosage should always be determined by a healthcare professional.

General Guidelines

• Initial Dose: Often started at the lowest strength to monitor tolerance.

• Adjustment: Gradually increased based on patient’s response and heart rate.

• Administration: Take tablets with food to reduce dizziness or lightheadedness.

Missed Dose: Skip the missed dose and continue with the next scheduled dose. Do not double the dose. 

Price of Carvedilol and Ivabradine Tablets

The price of Carvedilol and Ivabradine Tablets can vary based on:

• Brand name: Carvediol Duo

• Strength (e.g., Carvedilol 3.125 mg + Ivabradine 5 mg, or other variations)

• Pack size: 10x14 Tablets

• Manufacturer: Steris Healthcare Pvt Ltd
   

In India, the cost generally ranges between ₹150 – ₹500 per strip depending on dosage and brand. For the most accurate price, check with your local pharmacy or trusted online medicine supplier.

Side Effects of Carvedilol and Ivabradine Tablets

Like all medicines, Carvedilol+Ivabradine can cause side effects. Most are mild and temporary, but some may require medical attention.

Common Side Effects

• Dizziness or lightheadedness

• Slow heartbeat (bradycardia)

• Fatigue

• Low blood pressure

• Visual disturbances (temporary brightness or halos)
   

Serious Side Effects (Seek medical help)

• Fainting spells

• Severe bradycardia

• Irregular heart rhythms

• Shortness of breath or swelling of legs

• Allergic reactions (rash, itching, swelling)
   

Precautions & Warnings

Before starting Carvedilol and Ivabradine Tablets, inform your doctor if you:

• Have severe liver problems

• Suffer from very low blood pressure

• Have conduction abnormalities in the heart (e.g., AV block)

• Are pregnant or breastfeeding

• Are taking other medications for heart disease

Avoid sudden discontinuation of the medicine, as it may worsen heart conditions.

Drug Interactions

Certain drugs can interact with Carvedilol and Ivabradine, including:

• Other heart rate-lowering medicines

• Strong CYP3A4 inhibitors (e.g., ketoconazole)

• Certain antihypertensives

• Digoxin
  Always provide a complete list of medicines to your healthcare provider.  

Why Choose Steris Healthcare for Carvedilol and Ivabradine Tablet

When it comes to heart health, quality, reliability, and patient safety should never be compromised. Steris Healthcare stands out as a trusted name in the pharmaceutical industry, offering Carvedilol and Ivabradine Tablets that meet the highest standards of manufacturing and efficacy. Each tablet is produced in state-of-the-art facilities following stringent Good Manufacturing Practices (GMP) to ensure purity, accuracy in dosage, and consistency in results.

At Steris Healthcare, we understand the critical role that Carvedilol+Ivabradine plays in managing chronic heart failure and angina. That’s why our formulations are developed with precision, ensuring optimal bioavailability and stability so patients receive maximum therapeutic benefit. Our focus on quality control means every batch undergoes rigorous testing for safety and effectiveness before reaching the market.

We are committed not just to delivering medicines, but to improving patient outcomes. Alongside high-quality products, we provide clear product labeling, detailed usage instructions, and professional customer support to assist healthcare providers and patients alike. By maintaining affordable pricing without compromising quality, Steris Healthcare ensures that life-saving medications remain accessible to those who need them most.