CEPHAHELIX 375 + Cephalexin (375mg): Uses, Benefits, Side Effects and Other....

Introduction

CEPHAHELIX 375 is a prescription medication containing Cephalexin (375mg), a cephalosporin antibiotic used to treat various bacterial infections. It is commonly prescribed for infections affecting the respiratory tract, urinary tract, skin, ears, and bones. As an effective bactericidal agent, Cephalexin works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death.

This antibiotic is widely recommended due to its broad-spectrum activity, safety profile, and effectiveness against Gram-positive and Gram-negative bacteria. It is used for mild to moderate infections and is often an alternative to penicillin-based antibiotics in patients allergic to penicillin.

How Cephalexin Works

Cephalexin is a first-generation cephalosporin antibiotic that interferes with bacterial cell wall formation. It binds to penicillin-binding proteins (PBPs), preventing the bacteria from maintaining their structural integrity, leading to bacterial lysis and death.

Unlike some other antibiotics, Cephalexin is effective against penicillin-resistant Staphylococcus aureus and certain strains of Streptococcus, E. coli, Klebsiella, and Proteus mirabilis. However, it is ineffective against MRSA (Methicillin-resistant Staphylococcus aureus) and certain anaerobic bacteria.

Key Uses of CEPHAHELIX 375

CEPHAHELIX 375 is primarily used to treat bacterial infections, including:

1. Respiratory Tract Infections

• Pharyngitis & Tonsillitis – Caused by Streptococcus pyogenes, leading to sore throat and fever.

• Pneumonia & Bronchitis – Effective against bacterial pneumonia and acute bronchitis due to susceptible pathogens.

• Sinusitis & Otitis Media – Treats bacterial infections in the sinuses and middle ear.

2. Urinary Tract Infections (UTIs)

• Effective against E. coli, Proteus mirabilis, and Klebsiella pneumoniae responsible for urinary infections.

• Used in uncomplicated cystitis, pyelonephritis, and urethritis.

3. Skin & Soft Tissue Infections

• Treats cellulitis, impetigo, and infected wounds caused by Staphylococcus aureus & Streptococcus pyogenes.

• Often used for abscesses, boils, and infected dermatitis.

4. Bone & Joint Infections

• Prescribed for osteomyelitis (bone infections) caused by Staphylococcus aureus.

5. Dental Infections

• Used for dental abscesses, gingivitis, and post-surgical infections.

6. Sexually Transmitted Infections (STIs)

• Sometimes prescribed for gonorrhea and chlamydia infections in combination with other antibiotics.

7. Prophylaxis Before Surgery

• Used to prevent bacterial infections before dental, orthopedic, and general surgeries in high-risk patients.

Dosage and Administration

Recommended Dosage

The dosage of CEPHAHELIX 375 depends on the type and severity of the infection, as well as the patient’s age and medical condition.

For Adults:

• Mild to moderate infections: 375 mg every 6 to 8 hours (four times a day).
• Severe infections: Up to 750 mg per dose every 6 hours.
• Urinary Tract Infections: 375 mg every 6-12 hours for 7-14 days.
• Respiratory Infections: 750 mg per day in divided doses.

For Children:

• 25-50 mg/kg/day, divided into 2 to 4 doses.
• Severe infections may require up to 100 mg/kg/day.

How to Take CEPHAHELIX 375

• Can be taken with or without food.
• Swallow the tablet whole with a glass of water.
• If stomach upset occurs, take it with food or milk.
• Complete the full course even if symptoms improve early.

Side Effects of CEPHAHELIX 375

Common Side Effects:

• Nausea & Vomiting

• Diarrhea (due to disruption of gut flora)

• Stomach Pain & Indigestion

• Headache & Dizziness

Serious Side Effects (Rare but Possible):

• Allergic Reactions (Rash, Itching, Swelling)
• Severe Diarrhea (Clostridium difficile infection)
• Liver Dysfunction (Jaundice, Dark Urine, Fatigue)
• Kidney Problems (Decreased Urination, Swelling of Feet & Ankles)
• Blood Disorders (Anemia, Unusual Bruising or Bleeding)

If any of these symptoms occur, seek medical attention immediately.

Precautions & Warnings

1. Allergy Alert

• Avoid CEPHAHELIX 375 if you are allergic to Cephalexin, Cephalosporins, or Penicillins.

• Patients with a history of severe allergic reactions (anaphylaxis) should avoid this antibiotic.

2. Kidney & Liver Disorders

• Patients with renal impairment need dose adjustments.

• Regular liver function tests may be needed for patients with liver disease.

3. Pregnancy & Breastfeeding

• Safe during pregnancy but should be used only if necessary.

• Excreted in breast milk; consult a doctor before use during lactation.

4. Drug Interactions

Cephalexin may interact with:

• Probenecid – Increases Cephalexin levels in the blood.

• Oral Anticoagulants (Warfarin) – May increase the risk of bleeding.

• Metformin – Can increase the risk of lactic acidosis.

• Live Vaccines (Typhoid Vaccine) – May reduce vaccine effectiveness.

5. Overdose Risks

• Overdosing can cause nausea, vomiting, stomach cramps, diarrhea, and seizures.
• Seek immediate medical help in case of overdose.

Comparisons with Other Antibiotics

Frequently Asked Questions (FAQs)

1. Can Cephalexin be used for viral infections?

No, CEPHAHELIX 375 is only effective against bacterial infections and does not work for viral infections like the flu or common cold.

2. How long does it take for Cephalexin to work?

Most people see improvement within 24-48 hours after starting treatment. However, it is crucial to complete the full course to prevent antibiotic resistance.

3. Can I consume alcohol while taking Cephalexin?

Yes, moderate alcohol consumption is unlikely to cause major interactions, but it may worsen side effects like nausea and dizziness.

4. Does Cephalexin cause diarrhea?

Yes, Cephalexin may disrupt gut bacteria, leading to mild to severe diarrhea. If diarrhea is severe, consult your doctor immediately.

5. Can Cephalexin treat STIs?

Cephalexin is not the first-line treatment for STIs, but it may be used in combination with other antibiotics for gonorrhea or chlamydia.

Conclusion

CEPHAHELIX 375 (Cephalexin 375mg) is a highly effective cephalosporin antibiotic for treating bacterial infections. It is widely used for respiratory, urinary, skin, bone, and soft tissue infections. Though generally well-tolerated, it may cause gastrointestinal disturbances and allergic reactions in some individuals.

For best results, take CEPHAHELIX 375 as prescribed, complete the full course, and avoid self-medication. Always consult a healthcare provider for appropriate dosage and safety measures.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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