Cilnidipine 20mg & Telmisartan 40mg ''''

Introduction

TELMISTRUM CLINI 40/10 is a combination medication containing Cilnidipine (10mg) and Telmisartan (40mg), which is primarily used for managing hypertension (high blood pressure). This combination effectively controls blood pressure levels, reducing the risk of cardiovascular complications such as stroke, heart attack, and kidney diseases.

Cilnidipine is a calcium channel blocker (CCB), while Telmisartan is an angiotensin II receptor blocker (ARB). Together, they work synergistically to lower blood pressure by relaxing blood vessels and improving blood flow.

Key Ingredients

Cilnidipine (10mg)

Cilnidipine is a dihydropyridine-type calcium channel blocker that acts on both L-type and N-type calcium channels. It is highly effective in reducing blood pressure by causing relaxation in the blood vessels. Unlike other calcium channel blockers, Cilnidipine has an added advantage of preventing sympathetic overactivity, reducing the risk of reflex tachycardia.

Telmisartan (40mg)

Telmisartan belongs to the angiotensin II receptor blocker (ARB) class, which works by inhibiting angiotensin II from binding to its receptors. This action prevents vasoconstriction, leading to widening of blood vessels and ultimately lowering blood pressure levels. Telmisartan also provides renal protection, making it suitable for patients with diabetes and kidney-related hypertension.

How Does TELMISTRUM CLINI 40/10 Work?

TELMISTRUM CLINI 40/10 effectively manages blood pressure through a dual mechanism:

1. Cilnidipine: Blocks calcium influx in both L-type and N-type calcium channels, leading to smooth muscle relaxation and reduction in vascular resistance.

2. Telmisartan: Blocks angiotensin II receptors, preventing vasoconstriction and fluid retention, leading to better blood pressure control.

This combined effect ensures sustained blood pressure reduction with minimal side effects.

Uses of TELMISTRUM CLINI 40/10

• Hypertension (High Blood Pressure): Controls blood pressure effectively and prevents complications.

• Cardiovascular Protection: Reduces the risk of heart attacks and strokes.

• Kidney Protection: Helps in protecting kidney function, especially in hypertensive and diabetic patients.

• Reduced Sympathetic Activity: Cilnidipine prevents excessive sympathetic nervous system activation, making it beneficial for patients prone to tachycardia.

Dosage and Administration

• Recommended Dose: Usually one tablet per day, taken at the same time daily for optimal results.

• With or Without Food: Can be taken with or without food as directed by a healthcare professional.

• Do Not Miss a Dose: If a dose is missed, take it as soon as possible. However, if it's almost time for the next dose, skip the missed dose and continue the regular schedule.

• Avoid Overdose: Taking more than the prescribed dose can lead to severe hypotension and dizziness.

Side Effects of TELMISTRUM CLINI 40/10

While TELMISTRUM CLINI 40/10 is generally well tolerated, some individuals may experience mild side effects such as:

• Dizziness or Lightheadedness

• Swelling in the Ankles or Feet (Peripheral Edema)

• Fatigue or Weakness

• Headache

• Flushing (Redness of Skin)

• Nausea or Stomach Discomfort

Rare but serious side effects include:

• Severe Hypotension (Low Blood Pressure)

• Irregular Heartbeat (Arrhythmia)

• Kidney Dysfunction

• Liver Problems

If any of these severe symptoms occur, seek immediate medical attention.

Precautions and Warnings

• Pregnancy and Breastfeeding: Not recommended for pregnant or breastfeeding women, as it may harm the baby.

• Liver and Kidney Disease: Patients with pre-existing liver or kidney disorders should use this medication under strict medical supervision.

• Avoid Alcohol: Alcohol consumption can exacerbate dizziness and increase the risk of hypotension.

• Electrolyte Imbalance: Regular monitoring of potassium levels is necessary, as Telmisartan can cause hyperkalemia (high potassium levels).

• Driving and Machinery Use: Avoid activities that require mental alertness if experiencing dizziness or drowsiness.

Drug Interactions

Certain medications can interact with TELMISTRUM CLINI 40/10, altering its effectiveness. Inform your doctor if you are taking:

• Diuretics (Water Pills) – May cause excessive low blood pressure.

• NSAIDs (Pain Relievers) – Can reduce the blood pressure-lowering effect.

• Other Antihypertensive Drugs – May lead to excessive hypotension.

• Potassium Supplements or Potassium-Sparing Diuretics – Increases the risk of hyperkalemia.

• Antidiabetic Medications – Blood sugar levels should be closely monitored.

Benefits of TELMISTRUM CLINI 40/10

• Superior Blood Pressure Control: A combination of two potent antihypertensive agents for better BP management.

• Reduced Risk of Cardiovascular Diseases: Prevents heart attacks, strokes, and heart failure.

• Prevention of Kidney Damage: Beneficial for hypertensive diabetic patients.

• Lower Incidence of Reflex Tachycardia: Cilnidipine’s unique mechanism ensures stable heart rate control.

• Once-Daily Dosing: Ensures better patient compliance.

Storage Instructions

• Store in a cool, dry place away from direct sunlight and moisture.

• Keep out of reach of children.

• Do not use if the expiry date has passed.

Frequently Asked Questions (FAQs)

1. Can TELMISTRUM CLINI 40/10 be used for all types of hypertension?

Yes, it is effective for mild to moderate hypertension. However, for severe hypertension, additional medications may be required.

2. Can I stop taking TELMISTRUM CLINI 40/10 once my blood pressure is controlled?

No. Blood pressure control is a long-term commitment. Stopping the medication suddenly may cause rebound hypertension.

3. How long does TELMISTRUM CLINI 40/10 take to show effects?

It starts working within a few hours, but full benefits are observed after 2-4 weeks of regular use.

4. Can elderly patients take this medication?

Yes, but lower doses may be recommended depending on their renal and hepatic function.

5. What should I do if I experience severe dizziness after taking TELMISTRUM CLINI 40/10?

Lie down and stay hydrated. If symptoms persist, consult your doctor immediately.

Conclusion

TELMISTRUM CLINI 40/10 (Cilnidipine 10mg & Telmisartan 40mg) is an effective and well-tolerated medication for managing hypertension. Its dual-action mechanism provides better blood pressure control, cardiovascular protection, and reduced sympathetic activity. With once-daily dosing and minimal side effects, it is a preferred choice for hypertensive patients. However, proper medical guidance and regular monitoring are essential for safe use. Always follow your doctor’s instructions for optimal health outcomes.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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