Clomiphene (25mg) : Uses, Benefits, Dosage, Pice & Side Effects ..

May 06, 2024

Introduction

CLOMIFINE 25 contains Clomiphene Citrate 25 mg, a powerful fertility medication commonly used to stimulate ovulation in women and improve sperm parameters in men. It is a selective estrogen receptor modulator SERM that mimics anti-estrogen effects at the hypothalamus, resulting in increased production of FSH and LH which are key hormones for reproduction.This low-dose formulation is specially tailored for patients needing gentle ovulation induction, offering minimal side effects with optimal efficacy.

Key Features and Composition

Key Features of CLOMIFINE 25

  • Mild dosage ideal for gradual hormonal regulation

  • Cost-effective fertility solution for men and women

  • Reduced risk of multiple pregnancies compared to higher doses

  • Suitable for PCOS, hypogonadism, and idiopathic infertility

  • Manufactured in WHO GMP certified facilities ensuring quality and safety

Composition

  • Active Ingredient: Clomiphene Citrate 25 mg

  • Excipients: Pharmaceutical-grade inert ingredients for stability and absorption

Mechanism of Action

Clomiphene binds to estrogen receptors in the hypothalamus and blocks estrogenic feedback, which stimulates the release of gonadotropins

In Women: Increased FSH promotes follicular development, and LH surge triggers ovulation
In Men: Enhances testicular stimulation, promoting spermatogenesis and increasing testosterone levels

Effective for

  • Inducing ovulation

  • Restoring menstrual regularity

  • Boosting testosterone

  • Improving sperm quality

Usage and Indications

Indicated in Women For

  • Ovulatory dysfunction

  • Polycystic Ovary Syndrome PCOS

  • Luteal phase defects

  • Clomiphene challenge tests

  • First-line therapy in unexplained infertility

Indicated in Men For

  • Oligospermia low sperm count

  • Non-obstructive azoospermia

  • Hypogonadotropic hypogonadism

  • Low testosterone due to secondary causes

Dosage Guidelines

Women

  • Start with 25 to 50 mg daily from Day 2 to 5 of the cycle for 5 days

  • Ovulation typically occurs 5 to 10 days after the last dose

  • Monitor follicle growth using ultrasound and hormone levels

Men

  • 25 mg daily or alternate days for 3 to 6 months

  • Requires regular semen analysis and hormone testing

Always consult a fertility specialist before use. Dosage may vary based on patient condition and response.

Benefits of CLOMIFINE 25

  • Promotes natural ovulation without hormone injections

  • Improves fertility outcomes in PCOS and hormonal imbalance

  • Boosts sperm count and testosterone levels in males

  • Restores regular menstrual cycles in women

  • Non-invasive oral treatment with wide availability

  • Affordable and safe first-line therapy

  • Can be combined with IUI or ART for better results

  • Lower dose reduces risk of multiple births and side effects

Precautions and Side Effects

Common Side Effects

  • Hot flashes

  • Mood swings

  • Abdominal pain

  • Breast tenderness

  • Headache

  • Bloating

Rare but Serious Risks

  • Ovarian Hyperstimulation Syndrome OHSS

  • Visual disturbances blurry or double vision

  • Enlarged ovaries

  • Cyst formation

  • Multiple pregnancy twins or triplets

Contraindications
Not recommended in pregnancy, liver disease, abnormal uterine bleeding, and untreated thyroid or adrenal disorders

Monitoring Required
Baseline hormone profile, pelvic ultrasound, and liver function tests

Frequently Asked Questions

1. Can CLOMIFINE 25 be used in lean PCOS patients
Yes. Low-dose Clomiphene is ideal for lean PCOS patients to avoid overstimulation and side effects

2. How is CLOMIFINE 25 different from 50 mg
CLOMIFINE 25 offers a gentler approach and reduces the chance of side effects like ovarian hyperstimulation and multiple pregnancies. It is ideal for sensitive individuals

3. Can this be used for male infertility
Yes. It is prescribed for idiopathic oligospermia and low testosterone levels in men with good success over three to six months

4. What is the success rate of CLOMIFINE 25
Ovulation occurs in 70 to 80 percent of women. Conception rates are about 30 to 40 percent per cycle with proper monitoring

5. Can CLOMIFINE 25 be used with IUI or IVF
Yes. It is used to enhance follicular response before intrauterine insemination IUI or as part of IVF protocols

6. Can CLOMIFINE 25 cause weight gain
Rarely. Some women may experience bloating or water retention, but significant weight gain is uncommon

Conclusion

CLOMIFINE 25 Clomiphene Citrate 25mg is a well-established treatment for infertility in both men and women. Its low-dose formulation ensures safety, flexibility, and effectiveness, making it a trusted choice for fertility management.With high success rates, minimal side effects, and affordability, CLOMIFINE 25 is a reliable first step toward a successful pregnancy.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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