Comprehensive OAB Relief: Mirabegron 50mg & Solifenacin 5mg

MIRAGRON S 50/5 

Mirabegron (ER) (50mg) and Solifenacin succinate (5mg)

Introduction

MIRAGRON S 50/5  Composition is Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg) is a powerful combination medication used to treat overactive bladder (OAB). This dual-action therapy leverages the benefits of Mirabegron, a beta-3 adrenergic agonist, and Solifenacin, an antimuscarinic agent. Together, they provide comprehensive relief from the disruptive symptoms of OAB, such as urinary urgency, frequency, and urge incontinence, offering patients a significant improvement in quality of life.

Uses of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

Treating Overactive Bladder (OAB)

The primary use of this combination is to manage overactive bladder symptoms. By targeting different pathways involved in bladder control, Mirabegron and Solifenacin work synergistically to provide more effective symptom relief than either drug alone.

Reducing Urinary Frequency and Urgency

Mirabegron works by relaxing the bladder muscle, increasing its capacity, and reducing the frequency of urination. Solifenacin reduces bladder contractions, helping to control the sudden, intense urge to urinate. This combination effectively decreases both the frequency and urgency of urination.

Managing Urge Incontinence

Urge incontinence, characterized by involuntary leakage of urine due to a sudden, strong need to urinate, is significantly reduced with this combination therapy. Patients experience fewer episodes of leakage, leading to improved confidence and quality of life.

Dosage of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

Standard Dosage

The recommended dose for adults is one tablet of Mirabegron (ER) 50mg and Solifenacin Succinate 5mg taken once daily. This dosage may be adjusted by the healthcare provider based on the patient's response and tolerability. The extended-release formulation of Mirabegron ensures a steady release of the medication throughout the day.

Administration Guidelines

Take the tablet orally, preferably with a glass of water. You can take it with or without meals. The tablet should be swallowed whole and not crushed, chewed, or divided to ensure proper release and absorption of the medication.

Missed Dose

Unless the following dose is almost due, a missing dose should be taken as soon as remembered. If so, proceed with the regular dosing plan and skip the missed dose. Never take two doses to make up for one that you missed.

Side Effects of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

Common Side Effects

• Dry Mouth: Solifenacin can cause dry mouth, which may be alleviated by drinking plenty of water and using sugarless gum or candies.
• Constipation: This is a common side effect of Solifenacin. Increasing dietary fiber and fluid intake can help manage this symptom.
• Headache: Headaches are a common side effect and can usually be managed with over-the-counter pain relievers.
• Increased Blood Pressure: Mirabegron may cause a rise in blood pressure. Regular monitoring is recommended, especially in those with a history of hypertension.

Serious Side Effects

• Urinary Retention: A few patients may have trouble entirely emptying their bladder. If symptoms of urinary retention occur, medical attention should be sought immediately.
• Severe Allergic Reactions: Although rare, severe allergic reactions such as rash, itching, swelling, and difficulty breathing require immediate medical attention.
• Tachycardia: An increased heart rate may occur with Mirabegron. Patients should report any significant changes in heart rate to their healthcare provider.

Price of Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg)

The price of this combination medication varies depending on the brand, pharmacy, and location. On average, a month's supply ranges from $200 to $400. Patients are advised to check with their healthcare provider and insurance plan for potential cost-saving options, including generic versions or patient assistance programs.

Conclusion

Mirabegron (ER) (50mg) and Solifenacin Succinate (5mg) offer an effective combination therapy for managing overactive bladder. By combining the benefits of a beta-3 adrenergic agonist and an antimuscarinic agent, this medication provides comprehensive relief from urinary urgency, frequency, and urge incontinence. While generally well-tolerated, it is important to be aware of potential side effects and follow the prescribed dosage and administration guidelines. Regular consultation with a healthcare provider ensures safe and effective use of this combination therapy, leading to improved bladder control and enhanced quality of life. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. For further information 

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