CONARIS 100 : Itraconazole

CONARIS 100, containing Itraconazole (100mg), is a potent antifungal medication designed to treat a variety of fungal infections. Fungal infections can affect different parts of the body, such as the skin, nails, mouth, throat, and internal organs. Itraconazole is a broad-spectrum antifungal agent that works by inhibiting the growth of fungi, making it a widely used treatment in both clinical and outpatient settings.

What is Itraconazole?

Itraconazole belongs to the azole class of antifungal drugs, which specifically inhibit the synthesis of ergosterol, an essential component of fungal cell membranes. This mechanism of action makes Itraconazole effective against a wide range of fungal infections, including both superficial and systemic infections.

Uses of CONARIS 100

CONARIS 100 is prescribed for treating various fungal infections, including:

• Dermatophytosis (ringworm): Infections that affect the skin, nails, and hair caused by dermatophytes.
• Onychomycosis: Fungal infections of the fingernails and toenails, often causing thickening and discoloration.
• Candidiasis: Infections caused by Candida species affecting areas such as the mouth (oral thrush), vagina (vaginal thrush), and other mucosal surfaces.
• Aspergillosis: A type of infection caused by Aspergillus fungi, often affecting the lungs.
• Blastomycosis, Histoplasmosis, and other systemic mycoses: These serious infections can occur when fungal spores are inhaled and spread throughout the body, particularly affecting immunocompromised patients.

Itraconazole is also sometimes used as a prophylactic treatment for preventing fungal infections in immunocompromised patients, such as those undergoing chemotherapy or organ transplants.

How CONARIS 100 Works

The active ingredient in CONARIS 100, Itraconazole, disrupts the production of ergosterol, a vital component of fungal cell membranes. By inhibiting the synthesis of ergosterol, Itraconazole compromises the integrity of the fungal cell wall, leading to cell death and preventing the further spread of infection. This action ensures that the fungal infection is treated effectively, providing relief from symptoms and aiding in the recovery process.

Dosage of CONARIS 100

The dosage of CONARIS 100 (Itraconazole 100mg) varies depending on the type and severity of the fungal infection:

• For skin infections (dermatophytosis): Typically, 100mg once or twice a day for up to 2 to 4 weeks, depending on the infection site.
• For onychomycosis (nail infections): A dose of 200mg once daily for 12 weeks is often prescribed. Alternatively, a pulse dosing regimen of 200mg twice daily for one week per month over a course of three months may be followed.
• For systemic infections (aspergillosis, blastomycosis, histoplasmosis): The dosage may be increased to 200mg to 400mg per day, depending on the infection’s severity and the patient’s response to treatment.

Itraconazole should be taken with food to enhance absorption, and it is important to adhere to the prescribed course, even if symptoms improve, to ensure the infection is fully treated.

Side Effects of CONARIS 100

Like all medications, CONARIS 100 may cause side effects in some patients. While many people tolerate Itraconazole well, some common side effects include:

• Headache and dizziness
• Fatigue
• Skin rashes and itching
• Liver toxicity: Signs include yellowing of the skin or eyes (jaundice), dark urine, and severe fatigue.
• Heart problems: Itraconazole may cause or worsen heart failure in some individuals, particularly in patients with pre-existing heart conditions.
• Neurological effects: Numbness, tingling, or changes in vision may occur in rare cases.

Patients should notify their healthcare provider if they experience severe or persistent side effects.

Precautions and Interactions

Itraconazole, as found in CONARIS 100, may interact with several other medications, potentially altering their effectiveness or increasing the risk of side effects. Patients should inform their doctor about all the medications they are taking, especially:

• Antacids and acid reducers: These can interfere with Itraconazole absorption, reducing its effectiveness.
• Medications that affect liver enzymes (CYP3A4): Such as certain anticonvulsants, antibiotics, or HIV medications, which can affect how Itraconazole is processed in the body.
• Blood thinners, statins, and certain heart medications: These may have serious interactions with Itraconazole, leading to complications.

Patients with liver disease, heart failure, or those who are pregnant or breastfeeding should exercise caution and consult their doctor before starting treatment with CONARIS 100.

Price of CONARIS 100 in India

The price of CONARIS 100 (Itraconazole 100mg) may vary depending on the pharmacy and location. On average, a pack of 10 capsules can range from ₹250 to ₹500. Prices may fluctuate based on availability and manufacturer promotions, but Steris Healthcare ensures competitive pricing to make effective antifungal treatment accessible to all.

Conclusion

CONARIS 100, containing Itraconazole (100mg), is an essential antifungal medication that provides effective treatment for a range of fungal infections. Whether treating skin, nail, or systemic infections, Itraconazole offers a broad spectrum of action and is a trusted solution for both healthcare professionals and patients. When used as directed, CONARIS 100 can help manage fungal infections effectively, alleviating symptoms and preventing the further spread of infection. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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