Dabigatran Etexilate & DABIGATREX 150 Mg : STERIS PHARMA

DABIGATREX 150 Mg

Dabigatran Etexilate

DABIGATREX 150 is a medication that contains Dabigatran Etexilate, an anticoagulant used to prevent and treat blood clots. As a direct thrombin inhibitor, Dabigatran Etexilate plays a crucial role in managing various conditions related to blood clot formation. This article provides an in-depth look into DABIGATREX 150, covering its uses, dosage, side effects, composition, and more, ensuring a thorough understanding of this important medication.

Composition

DABIGATREX 150 contains:

• Dabigatran Etexilate: 150 mg

Mechanism of Action

Dabigatran Etexilate is a prodrug that is converted into its active form, Dabigatran, in the body. Dabigatran is a direct thrombin inhibitor, which means it directly binds to and inhibits the activity of thrombin, an enzyme essential for blood clot formation. By inhibiting thrombin, Dabigatran prevents the conversion of fibrinogen to fibrin, a key step in the clotting process, thereby reducing the risk of clot formation.

Uses

DABIGATREX 150 is prescribed for:

• Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE)
• Prevention of DVT and PE in patients who have undergone hip or knee replacement surgery

Dosage 

The dosage of DABIGATREX 150 should be individualized based on the patient's condition and response to treatment. Typically, the recommended doses are:

• For prevention of stroke and systemic embolism in non-valvular atrial fibrillation: 150 mg twice daily
• For treatment of DVT and PE: 150 mg twice daily after 5-10 days of parenteral anticoagulation
• For prevention of DVT and PE after hip or knee replacement surgery: 110 mg initially (1-4 hours post-surgery), then 220 mg once daily

Side Effects

Like any medication, DABIGATREX 150 may cause side effects. Common side effects include:

• Gastrointestinal disturbances (nausea, indigestion, stomach pain)
• Bleeding complications (nosebleeds, gum bleeding, bruising)
• Dyspepsia

Serious but rare side effects may include:

• Major bleeding events (gastrointestinal bleeding, intracranial hemorrhage)
• Allergic reactions (rash, itching, swelling, difficulty breathing)

Precautions and Warnings

• Bleeding Risk: Monitor for signs of bleeding and avoid activities that may increase the risk of injury.
• Kidney Function: Adjust dose in patients with renal impairment and monitor renal function periodically.
• Hypersensitivity: Avoid use in patients with known hypersensitivity to Dabigatran or any component of the formulation.
• Surgery and Procedures: Temporarily discontinue before certain surgical procedures to reduce the risk of bleeding.

Interactions

DABIGATREX 150 can interact with several medications, potentially altering their effects. Some notable interactions include:

• Antiplatelet Agents and NSAIDs: Increased risk of bleeding when used concurrently.
• P-glycoprotein Inhibitors: May increase Dabigatran exposure (e.g., ketoconazole, verapamil).
• P-glycoprotein Inducers: May decrease Dabigatran exposure (e.g., rifampin).

Monitoring

Regular monitoring is crucial to ensure the safe and effective use of DABIGATREX 150:

• Renal Function: Periodic assessment is necessary to adjust dosage as needed.
• Signs of Bleeding: Monitor for any signs of unusual bleeding or bruising.
• Hematocrit and Hemoglobin Levels: To detect any significant blood loss.

Lifestyle and Dietary Recommendations

• Diet: There are no specific dietary restrictions with Dabigatran, but maintain a balanced diet to support overall health.
• Hydration: Stay adequately hydrated to help maintain kidney function.
• Avoid Alcohol: Limit alcohol intake as it can increase the risk of gastrointestinal bleeding.

Conclusion

DABIGATREX 150, containing Dabigatran Etexilate, offers an effective solution for preventing and treating various thromboembolic conditions. Always consult with a healthcare provider for personalized advice and monitoring while using this medication. Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

CALL/WHATSAPP: 7877551268, 7849827488

BUY NOW