Desvenlafaxine ER (extended release) '

Desvenlafaxine ER (extended release) 
DVENAFAX 100

DVENAFAX 100 ER, a medication composed of Desvenlafaxine SR (100mg) ER, is primarily used in the treatment of depression, anxiety disorders, and other related mental health conditions. As a serotonin-norepinephrine reuptake inhibitor (SNRI), Desvenlafaxine plays a crucial role in the balance of serotonin and norepinephrine, chemicals in the brain that influence mood and emotional regulation. This article explores the uses, benefits, side effects, dosage recommendations, and other essential aspects of DVENAFAX 100 ER to provide a comprehensive understanding of its therapeutic effects.

What is DVENAFAX 100 ER?

DVENAFAX 100 ER is a brand name for Desvenlafaxine, which is a medication formulated to be extended-release (ER). This formulation allows for the controlled release of the active ingredient, providing continuous therapeutic levels throughout the day with the benefit of once-daily dosing. The primary component, Desvenlafaxine, belongs to a class of medications known as SNRIs, which are often prescribed to manage conditions like major depressive disorder (MDD) and generalized anxiety disorder (GAD).

How Does DVENAFAX 100 ER Work?

Desvenlafaxine works by increasing the levels of two important neurotransmitters in the brain: serotonin and norepinephrine. These chemicals play significant roles in regulating mood, emotion, and anxiety. By inhibiting their reuptake (or absorption back into nerve cells), Desvenlafaxine helps to maintain an optimal concentration of these neurotransmitters in the brain, thus promoting improved mood, reduced anxiety, and better emotional balance.

Uses of DVENAFAX 100 ER

The primary uses of DVENAFAX 100 ER include:

1. Major Depressive Disorder (MDD): Desvenlafaxine is commonly prescribed to treat depression, helping patients manage symptoms like sadness, hopelessness, fatigue, and lack of interest in activities.
2. Generalized Anxiety Disorder (GAD): It helps reduce feelings of anxiety, excessive worry, and fear that can interfere with daily activities and quality of life.
3. Other Related Disorders: In some cases, DVENAFAX 100 ER is used off-label to treat other mental health conditions such as panic disorders and social anxiety.

Dosage and Administration

The recommended starting dose of DVENAFAX 100 ER for most patients is 100mg per day. It is typically taken once daily, with or without food. However, healthcare providers may adjust the dosage based on individual patient needs, with some patients requiring a gradual increase to achieve optimal therapeutic effects.

• Initial Dose: 50mg to 100mg once daily.
• Maintenance Dose: 100mg once daily, which may be increased based on the patient's response.
• Maximum Dose: 400mg per day, though higher doses are rarely needed.

Precautions and Safety Information

Before starting DVENAFAX 100 ER, it is important to inform your healthcare provider about any pre-existing medical conditions, particularly:

• Liver or Kidney Issues: Desvenlafaxine is metabolized in the liver and excreted by the kidneys. Dose adjustments may be required for individuals with impaired liver or kidney function.
• History of Seizures: Patients with a history of seizures or conditions that may predispose them to seizures should use DVENAFAX 100 ER with caution.
• Hypertension: Desvenlafaxine may increase blood pressure. Regular monitoring of blood pressure is advised, especially in those with pre-existing hypertension.
• Serotonin Syndrome: A rare but serious condition caused by an excess of serotonin in the brain. Symptoms include agitation, hallucination, fever, fast heartbeat, muscle spasm or stiffness, tremor, and loss of coordination.

Side Effects of DVENAFAX 100 ER

Like all medications, DVENAFAX 100 ER can cause side effects, although not everyone will experience them. Common side effects include:

• Nausea
• Dry mouth
• Dizziness
• Fatigue
• Sweating
• Loss of appetite

Serious side effects are rare but can include:

• Elevated Blood Pressure
• Severe Allergic Reactions (such as rash, itching, swelling, or difficulty breathing)
• Eye Disorders (such as blurred vision)
• Suicidal Thoughts or Behavior: Antidepressants, including Desvenlafaxine, may increase the risk of suicidal thoughts or behaviors in children, adolescents, and young adults. Close monitoring is recommended during treatment, especially in the early stages.

Interactions with Other Medications

DVENAFAX 100 ER may interact with other medications, which could alter its effectiveness or increase the risk of side effects. Some notable interactions include:

• Monoamine Oxidase Inhibitors (MAOIs): A potentially life-threatening interaction, so there should be a washout period of at least 14 days between taking DVENAFAX 100 ER and MAOIs.
• Other Antidepressants (SSRIs, SNRIs): Combining Desvenlafaxine with other serotonergic medications may increase the risk of serotonin syndrome.
• Blood Thinners: Desvenlafaxine may increase the risk of bleeding when taken with blood-thinning medications.

Price of DVENAFAX 100 ER

The price of DVENAFAX 100 ER can vary depending on factors like the location, insurance coverage, and pharmacy. In India, the cost of a month’s supply of DVENAFAX 100 ER may range from ₹500 to ₹1500 for the generic version (Desvenlafaxine). Prices for branded formulations may be higher.

Conclusion

DVENAFAX 100 ER (Desvenlafaxine SR 100mg ER) is an effective medication for treating depression, anxiety, and other mental health conditions by balancing the neurotransmitters in the brain. While it can be highly beneficial, it is essential to use it under the supervision of a healthcare professional due to the potential for side effects and drug interactions. By following prescribed dosages and monitoring any changes in health, patients can enjoy significant relief from the symptoms of depression and anxiety, leading to an improved quality of life. Always consult a healthcare provider before starting, stopping, or altering the dosage of any medication. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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