Diltiazem Hydrochloride 120mg – The Ultimate Medication for Hypertension & Heart Health

Introduction:

Diltiazem Hydrochloride (120mg), marketed under the brand name DILTIAZONE SR 120, is a prescription medication primarily used in the management of hypertension (high blood pressure) and certain types of heart conditions. As a calcium channel blocker (CCB), it helps to relax and widen blood vessels, thereby improving blood flow and reducing the heart’s workload. DILTIAZONE SR 120 is a sustained-release formulation, offering a controlled release of the active ingredient over an extended period, which ensures steady therapeutic effects with fewer doses throughout the day.

Calcium channel blockers like Diltiazem are crucial in the treatment of cardiovascular conditions because they interfere with calcium ions entering the heart and vascular smooth muscle cells. This helps in managing conditions like arrhythmias, angina, and even preventing certain complications related to hypertension.

This article provides a deep dive into the uses, benefits, dosage, side effects, and other essential points of DILTIAZONE SR 120.

How Diltiazem Hydrochloride Works

Diltiazem Hydrochloride (120mg) works by inhibiting the movement of calcium ions across cell membranes in the heart and blood vessels. Calcium is essential for muscle contraction, and by blocking its entry into the cells, DILTIAZONE SR 120 effectively reduces the contraction of the heart muscles and blood vessels. The resulting effect is the relaxation and dilation of blood vessels, which leads to lower blood pressure and reduced strain on the heart.

In addition to lowering blood pressure, DILTIAZONE SR 120 can also be used to treat certain arrhythmias (irregular heartbeats) by stabilizing electrical impulses in the heart. The sustained-release formulation provides a gradual effect, making it easier to maintain constant blood levels of the medication over the day.

Benefits of Diltiazem Hydrochloride (120mg)

1. Management of Hypertension:

The primary benefit of DILTIAZONE SR 120 is its effectiveness in lowering blood pressure. By relaxing blood vessels, it reduces the resistance the heart faces while pumping blood. This not only helps reduce the likelihood of stroke and heart failure but also prevents other complications like kidney damage or eye problems, which can be caused by high blood pressure.

2. Treatment of Angina:

Diltiazem Hydrochloride (120mg) is also prescribed for angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. By relaxing coronary arteries and improving blood flow to the heart muscle, DILTIAZONE SR 120 helps reduce the frequency and intensity of angina attacks.

3. Control of Certain Arrhythmias:

Diltiazem is effective in controlling supraventricular tachycardia (SVT) and atrial fibrillation (AF). These are conditions where the heart beats irregularly or too quickly, disrupting normal heart function. The medication helps slow down the heart rate and restore a more regular rhythm.

4. Sustained-Release Benefits:

One of the key advantages of DILTIAZONE SR 120 is the sustained-release formulation, which allows for gradual absorption and a steady release of the medication over time. This means fewer doses are needed throughout the day, ensuring better adherence to the prescribed regimen.

5. Potential for Preventing Heart Failure Progression:

In some studies, calcium channel blockers like Diltiazem Hydrochloride (120mg) have shown potential in improving heart function in patients with heart failure. By lowering the blood pressure and reducing the heart’s workload, it helps the heart pump more efficiently and may prevent the worsening of heart failure symptoms.

Dosage and Administration of Diltiazem Hydrochloride (120mg)

The dosage of Diltiazem Hydrochloride (120mg) depends on the individual’s health condition, the severity of the disease, and how the body responds to the treatment. DILTIAZONE SR 120 is typically taken once a day, and the tablet should be swallowed whole. It should not be chewed, crushed, or split, as doing so can affect the sustained-release mechanism.

For hypertension or angina management, the typical starting dose is 120mg once a day. Depending on the patient’s response, the dose may be increased. The maximum recommended dose for DILTIAZONE SR 120 is usually 240mg to 360mg per day.

It is important to follow the healthcare provider’s instructions and not to adjust the dose without consultation, as doing so could lead to adverse effects or ineffective treatment.

Side Effects of Diltiazem Hydrochloride (120mg)

Like all medications, DILTIAZONE SR 120 can cause side effects. However, not everyone will experience these side effects. The following are common and serious side effects associated with Diltiazem Hydrochloride (120mg):

Common Side Effects:

• Dizziness or lightheadedness: This can occur when standing up too quickly, especially during the initial days of treatment.
• Headache: A common side effect due to the vasodilatory effects of the drug.
• Fatigue or tiredness: The relaxing effect on blood vessels can lead to an overall feeling of tiredness or lethargy.
• Nausea or constipation: Some individuals may experience gastrointestinal discomfort.

Serious Side Effects:

• Severe low blood pressure (hypotension): If the blood pressure drops too much, it can cause fainting, dizziness, or shock.
• Heart block or slow heart rate: As Diltiazem affects the electrical impulses of the heart, it may cause bradycardia (slow heart rate) or heart block in some patients.
• Swelling (edema): Swelling in the legs, ankles, or feet can occur, especially in patients with pre-existing heart conditions.
• Shortness of breath: This may indicate a worsening of heart failure or another serious heart issue.

If any of these severe reactions occur, it’s important to seek immediate medical attention.

Precautions and Interactions

Before starting DILTIAZONE SR 120, patients should inform their healthcare provider about any existing medical conditions, especially those involving the heart, liver, or kidneys. Diltiazem Hydrochloride (120mg) should be used with caution in individuals with a history of heart failure, liver disease, or kidney impairment.

Drug Interactions:

• Beta-blockers: Combining Diltiazem with beta-blockers like propranolol can lead to an excessive slowing of the heart rate or low blood pressure.
• Digoxin: When taken with digoxin, a medication for heart failure, Diltiazem can increase the risk of bradycardia or heart block.
• CYP3A4 Inhibitors: Certain medications that inhibit the CYP3A4 enzyme (e.g., ketoconazole, ritonavir) may increase the concentration of Diltiazem, leading to potential toxicity.

It’s important to inform the doctor about all the medications being taken, including over-the-counter drugs and herbal supplements, to avoid harmful interactions.

When Not to Use Diltiazem Hydrochloride (120mg)

There are certain situations where DILTIAZONE SR 120 should not be used, including:

• Severe bradycardia: Diltiazem should not be used if the heart rate is already too slow.
• Second- or third-degree heart block: Patients with certain types of heart block should avoid DILTIAZONE SR 120 unless they have a pacemaker.
• Severe hypotension: Patients with extremely low blood pressure should not take this medication.

Pregnant and breastfeeding women should consult their doctor before taking DILTIAZONE SR 120, as the effects on a developing fetus or infant are not fully known.

Conclusion

Diltiazem Hydrochloride (120mg), sold under the brand name DILTIAZONE SR 120, is a highly effective medication used to manage hypertension, angina, and certain arrhythmias. Its sustained-release formulation allows for consistent blood levels and fewer daily doses, offering convenience and improved patient adherence. Like any medication, DILTIAZONE SR 120 comes with potential side effects and interactions that should be monitored by a healthcare professional. However, when used as prescribed, it provides significant benefits in managing cardiovascular health. Before beginning treatment with Diltiazem Hydrochloride (120mg), it's crucial to have a thorough discussion with a healthcare provider to ensure it’s the right choice for the individual’s medical needs and to minimize the risk of adverse effects.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW