DISULFREE: Harnessing Disulfiram (500mg) for Effective Alcohol Addiction Treatment..

Jul 16, 2024

DISULFREE 

Dislufiram (500mg) 

DISULFREE, containing Disulfiram (500mg), is a medication widely used in the treatment of alcohol dependence and addiction. This article explores the mechanisms of Disulfiram, its therapeutic uses, dosage guidelines, potential side effects, and availability, providing valuable insights for individuals seeking to understand its role in alcohol addiction treatment.

Understanding Disulfiram

Disulfiram is a medication that works as a deterrent to alcohol consumption by causing unpleasant effects when alcohol is ingested. It inhibits the enzyme aldehyde dehydrogenase, which is involved in the metabolism of alcohol. As a result, acetaldehyde, a toxic byproduct of alcohol metabolism, accumulates in the body, leading to symptoms such as nausea, vomiting, headache, palpitations, and flushing.

Uses and Benefits of DISULFREE

Alcohol Dependence Treatment

DISULFREE is primarily used as part of a comprehensive treatment program for alcohol dependence. By inducing unpleasant effects upon alcohol consumption, it serves as a deterrent, helping individuals maintain sobriety and reduce the risk of relapse. This mechanism of action makes it particularly effective in supporting long-term abstinence from alcohol.

Supportive Therapy

In addition to its role in alcohol dependence treatment, DISULFREE may also be used in supportive therapy for individuals undergoing behavioral therapies or counseling for alcohol addiction. It reinforces behavioral changes and promotes adherence to treatment plans by discouraging alcohol consumption through its aversive effects.

Off-label Uses

Outside of alcohol dependence treatment, Disulfiram has shown potential in research for treating conditions such as cocaine addiction and certain types of cancer. However, these uses are considered off-label and should be explored under medical supervision and guidance.

Mechanism of Action

DISULFREE exerts its effects by inhibiting aldehyde dehydrogenase, an enzyme crucial for metabolizing acetaldehyde into acetic acid. When alcohol is consumed, acetaldehyde levels rise sharply, leading to the unpleasant symptoms characteristic of the Disulfiram reaction. This aversive reaction serves as a psychological and physiological deterrent to alcohol consumption.

Dosage and Administration

Recommended Dosage

  • DISULFREE (Disulfiram 500mg): The standard dosage is usually 500 mg once daily, taken preferably in the morning with water. Dosage adjustments may be made by healthcare providers based on individual patient response and tolerability.

Administration

  • DISULFREE should be taken exactly as prescribed by healthcare providers to achieve optimal therapeutic outcomes.
  • It is crucial to abstain from alcohol for at least 12 hours before starting DISULFREE to avoid triggering a Disulfiram reaction.

Potential Side Effects

While generally well-tolerated, DISULFREE may cause mild to severe side effects in some individuals, including:

  • Disulfiram Reaction: Symptoms can include flushing, nausea, vomiting, headache, dizziness, and palpitations when alcohol is consumed.
  • Fatigue
  • Metallic or garlic-like taste
  • Liver toxicity: Rarely, Disulfiram can cause liver damage, so regular monitoring of liver function is recommended during treatment.

Patients experiencing severe or persistent side effects should seek immediate medical attention. It is essential to inform healthcare providers about any existing medical conditions or medications to prevent adverse reactions.

Contraindications and Precautions

Certain conditions may warrant caution or avoidance of DISULFREE:

  • Allergies: Individuals with known allergies to Disulfiram or related compounds should not use DISULFREE.
  • Severe Heart Disease: Disulfiram may exacerbate certain heart conditions; consultation with a healthcare provider is advised.
  • Pregnancy and Breastfeeding: Safety during pregnancy and breastfeeding has not been established; DISULFREE should be used with caution or avoided during these periods.

Availability and Pricing

DISULFREE (Disulfiram 500mg) is available through pharmacies with pricing varying based on dosage strength, formulation, and geographic location. Patients are encouraged to inquire locally or online for accurate pricing information.

Conclusion

DISULFREE, containing Disulfiram (500mg), plays a crucial role in alcohol addiction treatment by discouraging alcohol consumption through aversive effects. Its ability to induce a Disulfiram reaction serves as a powerful deterrent, supporting individuals in their journey towards sobriety and reducing the risk of relapse. When used as part of a comprehensive treatment plan under medical supervision, DISULFREE offers an effective strategy for managing alcohol dependence and promoting long-term recovery. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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