Effective Use of Tacrolimus (0.25mg) in Treating Skin Conditions

Jul 25, 2024

Introduction

TACRENOLIME 0.25 contains Tacrolimus 0.25mg, a powerful immunosuppressive medication used primarily to prevent organ rejection in patients undergoing kidney, liver, or heart transplants. Tacrolimus is a calcineurin inhibitor that helps reduce immune system activity, allowing the body to accept the transplanted organ.

Key Features and Composition

  • Brand Name: TACRENOLIME 0.25

  • Active Ingredient: Tacrolimus (0.25mg)

  • Drug Class: Immunosuppressant / Calcineurin Inhibitor

  • Form: Oral Capsule

  • Manufacturing: WHO-GMP certified facilities

  • Packaging: Blister strips in protective packs

Usage and Indications

TACRENOLIME 0.25 is prescribed for:

  • Prevention of organ rejection post kidney, liver, or heart transplantation

  • Maintenance immunosuppression in transplant patients

  • Sometimes used in autoimmune conditions under specialist care

Dosage:

  • Usually started under medical supervision at 0.1–0.2 mg/kg/day, divided into two doses

  • TACRENOLIME 0.25 is often used in dose titration or maintenance phase

  • Exact dosage depends on blood levels and patient response

Benefits of TACRENOLIME 0.25

  • Highly effective in reducing the risk of organ rejection

  • Selective immunosuppression minimizes systemic side effects

  • Supports long-term graft survival

  • Can be combined with other immunosuppressants like mycophenolate mofetil or steroids

  • Available in multiple strengths for dose flexibility

How Tacrolimus Works

Tacrolimus inhibits calcineurin, a key enzyme in T-cell activation. By doing so, it prevents the immune system from attacking the transplanted organ. This makes it a first-line choice in post-transplant therapy.

Precautions and Side Effects

Common Side Effects:

  • Tremors

  • Headache

  • Nausea

  • High blood pressure

  • Increased blood sugar levels

Serious (but rare) Side Effects:

  • Kidney toxicity

  • Neurotoxicity

  • Increased infection risk

  • Diabetes mellitus post-transplant

Storage Instructions

  • Store at 20–25°C (68–77°F)

  • Keep away from moisture and direct sunlight

  • Do not freeze

  • Keep out of reach of children

Frequently Asked Questions (FAQs)

1. What is TACRENOLIME 0.25 used for?
It is used to prevent organ rejection in transplant patients and may be part of maintenance immunosuppression.

2. How should I take Tacrolimus?
Take it exactly as prescribed, usually twice daily on an empty stomach, at the same times every day.

3. Can I eat grapefruit while taking this medicine?
No, grapefruit and grapefruit juice should be avoided, as they can affect Tacrolimus levels.

4. Is regular blood monitoring required?
Yes, tacrolimus levels must be monitored regularly to ensure the right dosage and prevent toxicity.

5. Can TACRENOLIME 0.25 be used with other immunosuppressants?
Yes, it's often combined with mycophenolate, corticosteroids, or other agents based on the doctor’s protocol.

Conclusion

TACRENOLIME 0.25 (Tacrolimus 0.25mg) plays a vital role in modern transplant medicine, offering precise and effective immune system control to support long-term graft survival. With WHO-GMP quality assurance, it is a trusted option in post-transplant care.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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