Effective UTI Treatment: NITROTIME 100 (Nitrofurontoin 100mg)

Jun 19, 2024

Introduction

Nitrotime 100, containing Nitrofurantoin (100mg), is a widely used antibiotic for the treatment of urinary tract infections (UTIs). It is particularly effective against bacterial infections affecting the bladder and lower urinary tract. This medication belongs to the class of nitrofuran antibiotics, which work by stopping bacterial growth. Due to its strong antibacterial properties, Nitrotime 100 is commonly prescribed for both acute and recurrent UTIs.

This comprehensive guide provides insights into the uses, dosage, benefits, side effects, precautions, and more regarding Nitrotime 100.

What is Nitrofurantoin?

Nitrofurantoin is an antibiotic specifically designed to treat bacterial infections of the urinary tract. Unlike many other antibiotics, it concentrates in the urine, making it exceptionally effective against infections in the bladder. Nitrofurantoin is available in two forms: macrocrystals and monohydrate, with the macrocrystal form being absorbed more slowly into the bloodstream.

Uses of Nitrotime 100

1. Treatment of Urinary Tract Infections (UTIs)

Nitrotime 100 is primarily used to treat uncomplicated UTIs caused by Escherichia coli (E. coli), Enterococcus, Staphylococcus aureus, and other urinary pathogens.

2. Prevention of Recurrent UTIs

For individuals prone to recurrent urinary tract infections, Nitrotime 100 is often prescribed as a preventative measure to reduce bacterial infections in the urinary system.

3. Treatment of Cystitis

Cystitis, an inflammation of the bladder often caused by bacteria, can be effectively treated with Nitrofurantoin. The antibiotic clears the infection, relieving symptoms like painful urination, urgency, and frequent urination.

4. Post-Surgical UTI Prevention

After certain urological procedures, patients may be at risk of developing UTIs. Nitrotime 100 is sometimes prescribed as a prophylactic treatment to prevent bacterial growth.

How Nitrotime 100 Works

Nitrofurantoin works by damaging bacterial DNA, effectively killing or inhibiting bacterial growth. Unlike other antibiotics, it has a unique mechanism of action, making it effective against bacteria that have become resistant to other drugs. It is primarily active in the urinary tract, reducing systemic side effects.

Dosage and Administration

Recommended Dosage

The typical dosage of Nitrotime 100 varies depending on the condition being treated:

  • For acute UTIs: 100mg twice daily for 5 to 7 days

  • For prevention of recurrent UTIs: 50mg to 100mg once daily at bedtime

How to Take Nitrotime 100

  • Take the medication with food or milk to prevent stomach upset.

  • Swallow the capsule whole with a full glass of water.

  • Complete the full course of antibiotics even if symptoms improve early.

Side Effects of Nitrotime 100

Like all medications, Nitrotime 100 can cause some side effects. While most side effects are mild and temporary, some may require medical attention.

Common Side Effects:

  • Nausea and vomiting

  • Loss of appetite

  • Diarrhea

  • Headache

Serious Side Effects (Seek Medical Attention):

  • Lung problems: Shortness of breath, cough, or chest pain

  • Liver damage: Jaundice, dark urine, or persistent nausea

  • Peripheral neuropathy: Tingling or numbness in hands or feet

  • Severe allergic reactions: Rash, swelling, or difficulty breathing

Warnings and Precautions

Who Should Avoid Nitrotime 100?

  • Patients with kidney disease (severe renal impairment may reduce drug effectiveness)

  • Individuals with a history of liver problems due to Nitrofurantoin

  • Pregnant women in the last month of pregnancy (risk of hemolytic anemia in newborns)

  • Those with a history of lung or nerve problems related to Nitrofurantoin

Special Precautions

  • If symptoms persist after completing treatment, consult a doctor.

  • Avoid prolonged use to reduce the risk of lung toxicity or liver issues.

  • Stay hydrated to aid the elimination of bacteria.

  • Inform your doctor about any other medications you are taking, as interactions can occur.

Drug Interactions

Nitrotime 100 can interact with certain drugs, altering its effectiveness or increasing the risk of side effects. Some notable interactions include:

  • Antacids containing magnesium trisilicate – Reduce absorption of Nitrofurantoin

  • Probenecid and sulfinpyrazone – Decrease the elimination of Nitrofurantoin, increasing toxicity risk

  • Fluoroquinolone antibiotics (e.g., Ciprofloxacin) – Reduced effectiveness when taken together

Always inform your doctor about all medications, supplements, or herbal remedies you are using.

Nitrotime 100 and Pregnancy

Nitrofurantoin is considered safe in pregnancy, except in the final four weeks before delivery. It is categorized as Pregnancy Category B, meaning no proven risks in humans but caution is advised. Consult a healthcare professional before using Nitrotime 100 if pregnant.

Nitrotime 100 and Breastfeeding

Nitrofurantoin is excreted in small amounts in breast milk and is usually considered safe for breastfeeding mothers. However, it should be avoided in infants under 1 month old due to the risk of hemolytic anemia.

Storage and Handling

  • Store at room temperature (20-25°C) away from moisture and heat.

  • Keep out of reach of children.

  • Do not use expired medication.

Price and Availability

The price of Nitrotime 100 varies depending on the brand and pharmacy. Generally, a strip of 10 tablets costs between ₹100-₹300 in India. Prices may differ based on location, manufacturer, and availability.

Frequently Asked Questions (FAQs)

1. Can Nitrotime 100 be used for kidney infections?

Nitrofurantoin is not recommended for kidney infections (pyelonephritis) as it primarily acts in the bladder and does not reach high concentrations in kidney tissues.

2. How long does it take for Nitrotime 100 to work?

Symptoms typically improve within 24-48 hours, but completing the full course is crucial to prevent resistance.

3. Can I drink alcohol while taking Nitrotime 100?

Although alcohol does not directly interact with Nitrofurantoin, it may worsen nausea and dizziness, so it's best to avoid excessive alcohol consumption.

4. What should I do if I miss a dose?

Take the missed dose as soon as you remember, but skip it if it’s almost time for the next dose. Never double the dose to compensate.

5. Can Nitrotime 100 be used for children?

Nitrofurantoin can be prescribed for children above 1 month old under a doctor’s supervision.

Conclusion

Nitrotime 100 (Nitrofurantoin 100mg) is a highly effective antibiotic for treating and preventing urinary tract infections. With its unique action in the urinary tract, it remains one of the most reliable treatments for bladder infections. However, proper usage, adherence to dosage, and awareness of possible side effects are essential for optimal benefits.

If you experience persistent or severe symptoms, consult a healthcare provider immediately. Always take Nitrotime 100 as prescribed and complete the full course to prevent antibiotic resistance.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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