Empagliflozin and Metformin 12.5 mg Tablet: View Uses, Benefits, Dosage and Side Effects.

Apr 30, 2025

 

Managing type 2 diabetes effectively requires more than just lifestyle changes—it demands the right medication that can control blood sugar while supporting overall health. One such powerful combination is Empagliflozin and Metformin 12.5 mg Tablet, which blends two complementary agents: Empagliflozin 12.5 mg and Metformin Hydrochloride. This dual-action tablet not only helps in maintaining optimal blood glucose levels but also offers additional cardiovascular and metabolic benefits.

Whether you are newly diagnosed or transitioning from a single therapy, this medication may be an ideal choice under medical supervision. Let's explore its uses, benefits, dosage guidelines, and potential side effects to understand why this combination is increasingly recommended by healthcare providers.

What is Empagliflozin and Metformin 12.5 mg Tablet?

Empagliflozin and Metformin Hydrochloride Tablet is a fixed-dose combination medication used primarily for the treatment of type 2 diabetes mellitus. It brings together two antidiabetic agents:

Empagliflozin 12.5 mg – A sodium-glucose co-transporter 2 (SGLT2) inhibitor that helps remove excess glucose through urine.

Metformin Hydrochloride – A biguanide that reduces hepatic glucose production and improves insulin sensitivity.

Together, these drugs offer superior glycemic control while reducing the risk of cardiovascular complications in people with type 2 diabetes.

Uses of Empagliflozin and Metformin 12.5 mg Tablet

This medication is prescribed for:

  • Managing Type 2 Diabetes Mellitus
    It helps lower elevated blood sugar levels in adults with type 2 diabetes when diet and exercise alone are not enough.

  • Reducing Risk of Cardiovascular Events
    In diabetic patients with heart disease, Empagliflozin 12.5 mg is known to reduce the risk of hospitalization due to heart failure and cardiovascular death.

  • Promoting Weight Loss and Reducing Blood Pressure
    This combination may also support modest weight loss and a reduction in systolic blood pressure, adding to its overall therapeutic value.
     

Benefits of Empagliflozin 12.5 mg and Metformin Hydrochloride Combination

  • Dual Mechanism of Action
    While Empagliflozin 12.5 mg tablet eliminates excess glucose via the kidneys, Metformin suppresses glucose production in the liver and improves insulin response.

  • Improved Glycemic Control
    The combination results in better fasting and postprandial blood glucose regulation compared to either drug used alone.

  • Cardiovascular Protection
    Clinical studies suggest that Empagliflozin offers protection against cardiovascular events, a common risk in diabetic patients.

  • Weight and Blood Pressure Management
    Unlike some antidiabetic medications that lead to weight gain, this combination may promote slight weight loss and help reduce blood pressure.

  • Low Risk of Hypoglycemia
    When not combined with insulin or sulfonylureas, this medication has a minimal risk of causing dangerously low blood sugar levels.

Dosage and Administration

  • Typical Dosage: One tablet of Empagliflozin 12.5 mg and Metformin Hydrochloride is usually taken twice daily with meals to minimize gastrointestinal discomfort.

  • Adjustment: The exact dosage may vary depending on your blood sugar levels, renal function, and response to therapy. Your doctor may adjust the dose accordingly.

  • Missed Dose: If you miss a dose, take it as soon as you remember. If it's close to the next dose, skip the missed one—do not double the dose.

  • Important Advice:

    • Always take the tablet with food to reduce gastrointestinal side effects.

    • Stay hydrated, especially in hot weather or if exercising.

Side Effects of Empagliflozin and Metformin 12.5 mg Tablet

While generally well-tolerated, some patients may experience mild to moderate side effects, especially during the initial phase of treatment.

Common Side Effects

  • Nausea or upset stomach

  • Increased urination

  • Headache

  • Loss of appetite

  • Mild hypoglycemia (especially when used with insulin or sulfonylureas)

Serious (But Rare) Side Effects

  • Lactic Acidosis – A rare but serious condition linked to Metformin, especially in patients with kidney issues.

  • Genital Infections – Due to the sugar excreted in urine from Empagliflozin.

  • Dehydration – Resulting from increased urination.

  • Ketoacidosis – A rare side effect associated with SGLT2 inhibitors.
     

Seek immediate medical help if you experience symptoms like:

  • Severe abdominal pain

  • Difficulty breathing

  • Irregular heartbeat

  • Muscle pain with weakness
     

Precautions and Warnings

  • Not recommended for patients with type 1 diabetes or diabetic ketoacidosis.

  • Regular monitoring of kidney function is essential.

  • Inform your doctor if you have a history of heart disease, liver or kidney problems, or frequent urinary tract infections.

  • Avoid alcohol while on this medication to reduce the risk of lactic acidosis.

  • Not recommended during pregnancy or breastfeeding unless advised by a doctor.
     

Why Steris Healthcare Is the Best For Empagliflozin 12.5 mg and Metformin Hydrochloride.

Steris Healthcare's dedication to quality, innovation, and cost in pharmaceutical production makes it one of the top choices for Metformin Hydrochloride and Empagliflozin 12.5 mg. The business ensures that every formulation satisfies strict safety and effectiveness criteria by operating under worldwide guidelines and strict regulatory norms like WHO-GMP. This is especially crucial for combination treatments that are often used to treat type 2 diabetes, such as empagliflozin and metformin. Steris Healthcare produces dependable and consistent drugs by utilizing quality control methods and innovative production technology. 




 

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