ESMOSTRUM Domperidone (30mg), Esomeprazole (40mg) ): Uses , Side effect , Pictures and more.....

Jul 16, 2024

ESMOSTRUM D 

Domperidone (30mg), Esomeprazole (40mg)

ESMOSTRUM D is a combination medication containing Domperidone (30mg) and Esomeprazole (40mg). This combination is widely used to manage gastrointestinal disorders such as gastroesophageal reflux disease (GERD), dyspepsia, and other related conditions. This article explores the uses, dosage, side effects, and other essential aspects of ESMOSTRUM D.

Understanding Domperidone and Esomeprazole

Domperidone

 It works by enhancing gastrointestinal motility, facilitating the passage of food through the stomach, and preventing nausea and vomiting. Domperidone is particularly effective in conditions where gastric emptying is delayed.

Esomeprazole

 It reduces stomach acid production by blocking the enzyme system of gastric proton pumps. This action helps in managing acid-related conditions like GERD, peptic ulcers, and Zollinger-Ellison syndrome.

Uses of ESMOSTRUM D

Gastroesophageal Reflux Disease (GERD)

 Esomeprazole reduces the acid production, while Domperidone improves gastric motility, thus preventing reflux.

Dyspepsia

Dyspepsia, or indigestion, is another condition managed by ESMOSTRUM D. The combination of Domperidone and Esomeprazole alleviates symptoms such as bloating, nausea, and stomach discomfort by enhancing gastric emptying and reducing acid production.

Nausea and Vomiting

Domperidone’s antiemetic properties make ESMOSTRUM D effective in treating nausea and vomiting associated with various gastrointestinal disorders. It is particularly useful in managing these symptoms when they are due to delayed gastric emptying.

Dosage and Administration

Standard Dosage

The standard dosage of ESMOSTRUM D is one tablet per day, preferably taken before meals. However, the dosage may vary based on the severity of the condition and the patient’s response to the treatment. I

Special Populations

 It is crucial to consult a healthcare provider to determine the appropriate dosage for these populations.

Duration of Treatment

The duration of treatment with ESMOSTRUM D depends on the underlying condition and its severity. Short-term treatment is often sufficient for acute conditions, while chronic conditions like GERD may require long-term therapy. Regular follow-up with a healthcare provider is essential to monitor the treatment's effectiveness and adjust the dosage as needed.

Side Effects

Common Side Effects

  • Headache: Some patients may experience headaches as their body adjusts to the medication.
  • Diarrhea: Esomeprazole can sometimes cause diarrhea due to changes in stomach acid levels.
  • Abdominal Pain: Mild abdominal pain or discomfort is a possible side effect.
  • Dry Mouth: Domperidone can cause dry mouth in some patients.

Serious Side Effects

  • Cardiovascular Risks: Domperidone has been associated with an increased risk of cardiac arrhythmias. Patients with pre-existing heart conditions should use this medication with caution.
  • Severe Allergic Reactions: Rarely, patients may experience severe allergic reactions, including rash, itching, and swelling. 
  • Bone Fractures: Long-term use of Esomeprazole may increase the risk of bone fractures, particularly in older adults.

Precautions and Warnings

Drug Interactions

ESMOSTRUM D can interact with several medications, including:

  • Antibiotics: Certain antibiotics, such as clarithromycin, can increase the levels of Esomeprazole in the blood.
  • Antacids: Taking antacids simultaneously with ESMOSTRUM D can reduce the effectiveness of Esomeprazole.

Contraindications

  • Allergy: Patients with known allergies to Domperidone, Esomeprazole, or any other component of ESMOSTRUM D should avoid this medication.
  • Cardiac Conditions: Patients with severe cardiac conditions, particularly those involving arrhythmias, should use Domperidone with caution.
  • Liver Disease: Severe liver disease can affect the metabolism of both Domperidone and Esomeprazole, necessitating dosage adjustments.

Pregnancy and Breastfeeding

ESMOSTRUM D should be used during pregnancy only if clearly needed and prescribed by a healthcare provider. Both Domperidone and Esomeprazole can pass into breast milk; hence, caution is advised when administering this medication to breastfeeding mothers.

Conclusion

ESMOSTRUM D, a combination of Domperidone (30mg) and Esomeprazole (40mg), is an effective treatment for various gastrointestinal disorders, including GERD, dyspepsia, and nausea. Its dual action of enhancing gastric motility and reducing acid production provides comprehensive relief from these conditions. Regular monitoring and adherence to prescribed dosages can help manage the symptoms effectively while minimizing potential side effects. By understanding the uses, dosage, side effects, and precautions associated with ESMOSTRUM D, patients can make informed decisions about their treatment and achieve better management of their gastrointestinal health. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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