Everything You Need to Know About Mycophenolate Mofetil 250mg Tablets

Feb 21, 2025

Introduction

MYCOPLASM M 250 is a pharmaceutical formulation containing Mycophenolate Mofetil (250mg), an immunosuppressive drug widely used in organ transplantation and autoimmune conditions. This medication helps prevent organ rejection in patients who have undergone kidney, heart, or liver transplants. Additionally, Mycophenolate Mofetil is prescribed for treating certain autoimmune diseases like lupus nephritis and rheumatoid arthritis.

This article provides an in-depth look at MYCOPLASM M 250, including its uses, dosage, benefits, side effects, and precautions.

Key Ingredients

The main active ingredient in MYCOPLASM M 250 is:

  • Mycophenolate Mofetil (250mg) – A potent immunosuppressant that inhibits T-cell and B-cell proliferation, reducing the risk of organ rejection and controlling autoimmune responses.

How Does MYCOPLASM M 250 Work?

Mycophenolate Mofetil works by blocking an enzyme called inosine monophosphate dehydrogenase (IMPDH), which is essential for the production of guanine nucleotides in lymphocytes. By inhibiting this enzyme, MYCOPLASM M 250 prevents the proliferation of immune cells, thereby reducing the body’s ability to reject a transplanted organ and decreasing inflammation in autoimmune disorders.

Uses of MYCOPLASM M 250

1. Prevention of Organ Rejection

  • MYCOPLASM M 250 is primarily prescribed to prevent organ rejection in patients who have undergone a kidney, liver, or heart transplant.

  • It is usually given in combination with corticosteroids and other immunosuppressants like tacrolimus or cyclosporine.

2. Autoimmune Disorders

  • Lupus Nephritis: Helps reduce kidney inflammation in systemic lupus erythematosus (SLE).

  • Rheumatoid Arthritis: Controls excessive immune response and prevents joint damage.

  • Psoriasis: Used in some cases to suppress immune system activity.

Dosage and Administration

Standard Dosage

  • The typical dose of MYCOPLASM M 250 varies based on the condition being treated.

  • For organ transplant patients, the starting dose is usually 1g (1000mg) twice daily.

  • For autoimmune diseases, a lower dose, such as 500mg to 1g per day, may be prescribed.

Administration Guidelines

  • MYCOPLASM M 250 should be taken on an empty stomach (one hour before or two hours after meals) for better absorption.

  • Swallow the capsules whole with a glass of water.

  • Avoid breaking, chewing, or crushing the capsule.

Benefits of MYCOPLASM M 250

1. Effective Immunosuppression

  • Reduces the risk of transplant rejection and prolongs organ survival.

2. Better Tolerance

  • Compared to older immunosuppressants, Mycophenolate Mofetil has fewer toxic effects on the liver and kidneys.

3. Management of Autoimmune Diseases

4. Less Risk of Infections

  • Unlike corticosteroids, it does not cause significant bone loss or weight gain.

Possible Side Effects

While MYCOPLASM M 250 is generally well tolerated, it may cause some side effects, including:

Common Side Effects:

  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, and stomach pain.

  • Infections: Increased risk of bacterial, fungal, or viral infections.

  • Headache and dizziness.

Serious Side Effects:

  • Severe infections (pneumonia, sepsis)

  • Lymphoma or skin cancer (rare but possible with prolonged use)

  • Low blood cell count (anemia, leukopenia, thrombocytopenia)

  • Liver toxicity

Precautions and Warnings

1. Pregnancy and Breastfeeding

  • MYCOPLASM M 250 is not recommended during pregnancy due to a high risk of birth defects.

  • Women of childbearing age should use effective contraception while taking this medication.

2. Infection Risk

  • Patients taking Mycophenolate Mofetil are at increased risk of infections. Avoid crowded places and maintain good hygiene.

3. Vaccinations

  • Live vaccines (like measles, mumps, rubella, and yellow fever) should be avoided while taking MYCOPLASM M 250.

4. Blood Monitoring

  • Regular blood tests are required to monitor white blood cell count and kidney function.

Drug Interactions

Certain drugs may interact with MYCOPLASM M 250, altering its effectiveness or increasing side effects:

  • Antacids (Magnesium/Aluminum hydroxide): Reduce absorption of Mycophenolate Mofetil.

  • Rifampin: Lowers drug levels, making it less effective.

  • Acyclovir and Ganciclovir: Increase the risk of kidney damage.

  • Live Vaccines: Weakened immune response to vaccines.

Storage and Handling

  • Store MYCOPLASM M 250 at room temperature (20-25°C).

  • Keep it in a dry, cool place away from direct sunlight.

  • Keep out of reach of children.

Price of MYCOPLASM M 250 in India

The price of MYCOPLASM M 250 varies based on location and brand. Generally, a strip of 10 capsules costs between ₹250 to ₹500. Prices may fluctuate depending on pharmacy discounts and manufacturer offers.

Conclusion

MYCOPLASM M 250 (Mycophenolate Mofetil 250mg) is an essential immunosuppressant used in organ transplantation and autoimmune diseases. It effectively prevents organ rejection, manages autoimmune conditions, and provides a better safety profile compared to traditional immunosuppressants. However, proper monitoring and adherence to precautions are crucial to minimize side effects and ensure its maximum benefits. Always consult your doctor before starting or altering your dose.

For the best results, take MYCOPLASM M 250 exactly as prescribed and follow strict hygiene to reduce infection risks. If you experience severe side effects, seek immediate medical attention.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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