GLICLAGLAZE 80: USES, BENIFITES , PRICE AND OTHER DETAILES...

GLICLAGLAZE 80

Gliclazide (80mg)

Gliclaglaze 80 is a medication formulated with Gliclazide, an oral hypoglycemic agent belonging to the sulfonylurea class. Gliclazide (80mg) is widely used in the management of type 2 diabetes mellitus. This medication helps to control blood sugar levels by stimulating the release of insulin from the beta cells of the pancreas. Effective diabetes management is crucial to prevent complications such as neuropathy, nephropathy, and cardiovascular diseases.

How Gliclaglaze 80 Works
Gliclazide works by binding to sulfonylurea receptors on the surface of pancreatic beta cells, leading to the closure of ATP-sensitive potassium channels. This action causes depolarization of the beta cells and the subsequent opening of voltage-dependent calcium channels. The influx of calcium ions triggers the exocytosis of insulin-containing granules, resulting in increased insulin secretion. 

Uses of Gliclaglaze 80
Gliclaglaze 80 is primarily used to treat type 2 diabetes mellitus. It is especially beneficial for patients who cannot manage their blood sugar levels through diet and exercise alone. By improving insulin secretion, Gliclazide helps reduce fasting and postprandial blood glucose levels, thereby improving overall glycemic control. It is often prescribed in combination with other antidiabetic medications or as a monotherapy depending on the patient’s specific needs.

Dosage and Administration
The dosage of Gliclaglaze 80 should be individualized based on the patient’s blood sugar levels, response to treatment, and medical history. Typically, the initial dose is 40-80mg taken once daily. The dose may be gradually increased by 40-80mg increments until optimal blood glucose control is achieved. The maximum recommended daily dose is 320mg, which can be divided into two doses if necessary. It is advisable to take Gliclaglaze 80 with breakfast to reduce the risk of hypoglycemia.

Side Effects
Like any medication, Gliclaglaze 80 can cause side effects. While many patients tolerate it well, some may experience adverse reactions. Common side effects include:

Hypoglycemia: The most significant side effect, characterized by symptoms such as dizziness, sweating, palpitations, and confusion. It is crucial to monitor blood sugar levels regularly and be aware of the signs of low blood sugar.
Gastrointestinal Issues: Nausea, vomiting, abdominal pain, and diarrhea are possible but usually mild and transient.
Allergic Reactions: Rare but may include skin rashes, itching, and in severe cases, anaphylaxis.
Weight Gain: Some patients may experience a slight increase in weight due to improved insulin action and carbohydrate metabolism.
Safety Information
Contraindications: Gliclaglaze 80 is contraindicated in patients with a known hypersensitivity to Gliclazide or any of its excipients. It should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or severe renal or hepatic impairment.
Precautions: Regular monitoring of blood glucose levels is essential to avoid hypoglycemia. Patients should be educated on recognizing the symptoms of low blood sugar and the steps to take if it occurs. It is also important to inform healthcare providers of all medications being taken to avoid potential drug interactions.
Pregnancy and Lactation: Gliclaglaze 80 should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not recommended for use during breastfeeding due to the risk of hypoglycemia in the nursing infant.
Price of Gliclaglaze 80 in India
The cost of Gliclaglaze 80 can vary depending on the brand and the pharmacy. On average, the price of a strip of 10 tablets ranges from INR 50 to INR 100. 

Conclusion
Gliclaglaze 80, containing Gliclazide (80mg), is a valuable medication for managing type 2 diabetes mellitus. By enhancing insulin secretion, it helps control blood sugar levels, reducing the risk of diabetes-related complications. While generally well-tolerated, it is important to be aware of potential side effects and take necessary precautions to avoid hypoglycemia. Regular monitoring and consultation with healthcare providers ensure the safe and effective use of this medication. With proper management, patients with type 2 diabetes can lead healthier lives and reduce the risk of long-term complications.Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

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