Gliclazide 60mg (SR) Pioglitazone 15mg and Metformin HCL 500mg(SR) . .. . .

Type 2 Diabetes Mellitus (T2DM) is one of the fastest-growing lifestyle disorders in India, affecting millions of adults across urban and rural populations. Sedentary habits, unhealthy diets, stress, obesity, and genetic factors have made blood sugar imbalance a common long-term health challenge. Effective diabetes management often requires combination therapy to control blood glucose levels through multiple mechanisms.

TRIGLICLAGLAZE 60 is a scientifically formulated oral anti-diabetic medicine that combines Gliclazide 60 mg (Sustained Release), Pioglitazone 15 mg, and Metformin Hydrochloride 500 mg (Sustained Release). This triple-drug combination is designed to provide 24-hour blood sugar control, improve insulin sensitivity, and reduce insulin resistance—addressing the core defects of type 2 diabetes.

Manufactured with stringent quality standards, TRIGLICLAGLAZE 60 is prescribed for patients whose blood glucose levels are not adequately controlled with single or dual therapy. It offers a balanced, long-term solution for maintaining glycaemic stability and preventing diabetes-related complications.

Uses of TRIGLICLAGLAZE 60

Gliclazide and metformin hydrochloride tablets is primarily used for the treatment and long-term management of Type 2 Diabetes Mellitus in adults.

Main Uses

• Management of Type 2 Diabetes when diet and exercise alone are insufficient

• Patients not achieving target blood sugar levels with monotherapy

• Individuals requiring combination therapy for better glycaemic control

• Control of fasting blood glucose and postprandial blood glucose

• Reduction of insulin resistance in overweight or obese diabetic patients

How Each Component Works

• Gliclazide (SR): Stimulates pancreatic beta cells to release insulin in a controlled manner

• Pioglitazone: Improves insulin sensitivity in muscle and fat tissues

• Metformin (SR): Reduces glucose production in the liver and improves glucose uptake

Together, these medicines provide comprehensive glucose control throughout the day.

Benefits of TRIGLICLAGLAZE 60

 Gliclazide and metformin hydrochloride offers multiple clinical benefits, making it a preferred choice for physicians managing complex diabetes cases.

1. Triple-Action Blood Sugar Control

Works on insulin secretion, insulin sensitivity, and glucose production simultaneously.

2. Sustained Release Formulation

Both Gliclazide SR and Metformin SR ensure gradual drug release, reducing sudden sugar fluctuations.

3. Improved Insulin Sensitivity

Pioglitazone helps the body use insulin more effectively, especially beneficial in insulin-resistant patients.

4. Better Glycaemic Stability

Helps maintain consistent HbA1c levels over long-term use.

5. Reduced Risk of Diabetes Complications

Effective sugar control lowers the risk of nerve damage, kidney disease, heart issues, and vision problems.

6. Convenient Once-Daily or Prescribed Dosing

Enhances patient compliance compared to taking multiple tablets.

7. Suitable for Indian Lifestyle

Designed keeping Indian dietary patterns and metabolic needs in mind.

Dosage of TRIGLICLAGLAZE 60

The dosage of TRIGLICLAGLAZE 60 should be strictly followed as prescribed by a healthcare professional.

General Dosage Guidelines

• Usually taken once daily, preferably with or after meals

• Dosage may vary based on:

  • Blood glucose levels

  • Age

  • Kidney and liver function

  • Previous anti-diabetic therapy

Administration Instructions

• Swallow the tablet whole with water

• Do not crush, chew, or break the tablet

• Take the medicine at the same time every day

• Continue diet control and regular exercise along with medication

Missed Dose

• Take it as soon as you remember

• Skip the missed dose if it is close to the next dose

• Do not double the dose

Side Effects of TRIGLICLAGLAZE 60

Most patients tolerate TRIGLICLAGLAZE 60 well. However, some individuals may experience mild to moderate side effects.

Common Side Effects

• Nausea

• Stomach discomfort

• Diarrhea

• Headache

• Weight gain (due to Pioglitazone)

Less Common Side Effects

• Dizziness

• Fatigue

• Edema (swelling of feet or ankles)

• Increased appetite

Rare but Serious Side Effects

• Hypoglycaemia (low blood sugar), especially if meals are skipped

• Lactic acidosis (rare but serious, associated with Metformin)

• Liver function abnormalities

• Shortness of breath or sudden weight gain

Seek immediate medical attention if severe symptoms occur.

Gliclazide and metformin hydrochloride tablets price: for price please contact at steris healthcare.

Warnings

Before starting TRIGLICLAGLAZE 60, patients must be aware of certain important warnings.

• Not recommended for Type 1 Diabetes

• Should not be used in patients with severe kidney or liver disease

• Risk of hypoglycaemia increases with alcohol consumption

• Pioglitazone may cause fluid retention; caution in heart failure patients

• Long-term uncontrolled use without monitoring may lead to complications

Regular blood sugar monitoring is strongly advised.

Precautions

• Inform your doctor about any existing heart, kidney, or liver conditions

• Monitor blood glucose levels regularly

• Avoid excessive alcohol intake

• Maintain a balanced diet and physical activity

• Pregnant and breastfeeding women should use only if prescribed

• Inform your physician about all other medicines you are taking

Conclusion

TRIGLICLAGLAZE 60 is a well-balanced and effective triple-drug combination designed to tackle the complex nature of Type 2 Diabetes Mellitus. With the combined strength of Gliclazide 60 mg (SR), Pioglitazone 15 mg, and Metformin HCl 500 mg (SR), it provides comprehensive blood sugar control by improving insulin secretion, reducing insulin resistance, and limiting excess glucose production.

For Indian patients struggling to achieve target glycaemic levels with conventional therapies, gliclazide and metformin hydrochloride extended release tablets offers a reliable, convenient, and clinically proven option. When used alongside a healthy diet, regular exercise, and routine medical check-ups, it helps patients lead a healthier and more balanced life with diabetes under control.

Frequently Asked Questions (FAQs)

Q1. What is TRIGLICLAGLAZE 60 used for?

It is used for the management of Type 2 Diabetes Mellitus in adults.

Q2. Can TRIGLICLAGLAZE 60 be taken daily?

Yes, it is meant for daily use as prescribed by a doctor.

Q3. Does TRIGLICLAGLAZE 60 cause low blood sugar?

Hypoglycaemia may occur, especially if meals are skipped or taken irregularly.

Q4. Is this medicine suitable for long-term use?

Yes, when taken under medical supervision with regular monitoring.

Q5. Can elderly patients take TRIGLICLAGLAZE 60?

Yes, but dosage adjustments and close monitoring may be required.