Gliclazide SR 60mg

Introduction

Diabetes is a chronic condition that affects millions of people worldwide. It occurs when the body cannot properly regulate blood sugar levels, leading to higher than normal glucose concentrations in the bloodstream. There are various medications available to manage this condition, and Gliclazide SR 60 mg, marketed as GLICLAGALZE MR 60, is one such option.

Gliclazide is an oral medication that belongs to the class of drugs known as sulfonylureas. It is primarily used to treat Type 2 diabetes, especially when lifestyle changes like diet and exercise alone are insufficient to control blood sugar levels. The SR (sustained release) formulation of Gliclazide is designed to release the medication slowly, providing long-lasting effects and helping patients maintain stable blood glucose levels throughout the day.

In this article, we will explore the uses, benefits, dosage, side effects, and other relevant details about GLICLAGALZE MR 60 to help you better understand this medication and its role in diabetes management.

What is Gliclazide SR 60 mg?

Gliclazide is a second-generation sulfonylurea. Sulfonylureas are oral hypoglycemic agents that help lower blood sugar levels by stimulating the pancreas to release more insulin. Insulin is a hormone that helps the body use glucose for energy and maintain normal blood sugar levels.

The sustained release (SR) version of Gliclazide allows for gradual absorption in the body, which means that it helps manage blood sugar levels over a longer period, reducing the likelihood of blood sugar spikes or dips. The 60 mg dose is commonly used in patients who have Type 2 diabetes and need a more stable and controlled insulin release.

Key Benefits of Gliclazide SR 60 mg

1. Effective Blood Sugar Control: The primary benefit of GLICLAGALZE MR 60 is its ability to lower blood sugar levels in individuals with Type 2 diabetes. It works by stimulating the pancreas to release more insulin in response to meals, which helps in maintaining proper glucose metabolism.

2. Sustained Release for Long-Lasting Effect: The SR formulation ensures that the medication is released slowly over time. This helps in achieving a more stable blood glucose level throughout the day, reducing the risk of fluctuations and preventing hypoglycemia (low blood sugar).

3. Convenient Once-Daily Dosing: One of the most convenient aspects of GLICLAGALZE MR 60 is that it typically requires just one dose per day. This makes it easier for patients to adhere to their medication schedule, improving overall treatment compliance.

4. Reduces Insulin Resistance: In addition to stimulating insulin secretion, Gliclazide also works to improve the body’s sensitivity to insulin. This dual effect makes it particularly beneficial for patients with insulin resistance, a common feature of Type 2 diabetes.

5. Helps Prevent Complications: Proper blood glucose control can help prevent or delay the onset of diabetes-related complications such as kidney damage, nerve damage, vision problems, and cardiovascular disease. By maintaining stable blood glucose levels, GLICLAGALZE MR 60 plays a crucial role in long-term health management for diabetics.

How Does Gliclazide SR 60 mg Work?

Gliclazide works through its action on the pancreas. It binds to specific receptors on pancreatic beta cells, which leads to the release of insulin. This is important because, in Type 2 diabetes, the body either does not produce enough insulin or becomes resistant to it. By stimulating the pancreas to produce more insulin, Gliclazide helps the body process glucose more effectively.

In addition to this, Gliclazide may improve insulin sensitivity by reducing insulin resistance, meaning that the body’s cells are better able to respond to insulin. This helps in the efficient utilization of glucose and reduces the levels of circulating blood sugar.

The sustained release (SR) formulation means that the medication is absorbed gradually in the intestines, ensuring that Gliclazide SR 60 mg provides a steady amount of insulin release over time. This also reduces the risk of sudden drops in blood sugar levels (hypoglycemia), which is a common issue with immediate-release formulations.

Dosage and Administration

The typical starting dose of GLICLAGALZE MR 60 is one tablet taken once a day, usually with breakfast. The dosage may be adjusted depending on the individual’s blood sugar levels and the doctor’s recommendations. It is essential to follow the prescribed dosage and not adjust the dose without consulting a healthcare professional.

The 60 mg sustained-release tablet should be taken whole, without chewing or crushing, as doing so can interfere with the slow release of the medication. It is important to take the medication with food to prevent stomach upset and help ensure optimal absorption.

For optimal effectiveness, Gliclazide SR 60 mg should be taken alongside a healthy diet and exercise plan. Patients with diabetes should monitor their blood sugar regularly to ensure that the medication is working as expected.

Side Effects of Gliclazide SR 60 mg

Like all medications, Gliclazide SR 60 mg can cause side effects, though not everyone experiences them. Common side effects include:

1. Hypoglycemia (Low Blood Sugar): This is the most common side effect of Gliclazide. Symptoms of hypoglycemia can include sweating, shaking, dizziness, confusion, and blurred vision. It is essential to monitor blood sugar levels regularly and treat any episodes of low blood sugar immediately with a source of glucose (such as orange juice or glucose tablets).

2. Nausea and Vomiting: Some individuals may experience gastrointestinal issues, including nausea and vomiting. Taking the medication with food can help reduce these effects.

3. Weight Gain: As Gliclazide increases insulin levels, it can sometimes lead to weight gain. This is a common issue with sulfonylureas.

4. Skin Reactions: Allergic reactions, such as skin rashes, may occur in some individuals. If you notice any skin rashes or other allergic symptoms, contact your doctor immediately.

5. Dizziness and Fatigue: Some individuals may experience dizziness or fatigue, particularly when first starting the medication or when the dose is increased.

6. Liver Function Changes: Rarely, Gliclazide may cause liver issues. Routine monitoring of liver function is recommended during treatment.

7. Gastrointestinal Discomfort: Some patients may experience abdominal discomfort, bloating, or indigestion.

Precautions and Warnings

Before taking GLICLAGALZE MR 60, it is important to inform your healthcare provider about any medical conditions you may have, particularly:

1. Hypersensitivity to Gliclazide or other Sulfonylureas: If you are allergic to Gliclazide or any other ingredients in the medication, you should not take it.

2. Liver or Kidney Problems: Patients with liver or kidney impairments may need to use lower doses or alternative medications.

3. Pregnancy and Breastfeeding: Gliclazide SR 60 mg is not recommended during pregnancy, especially in the first trimester. If you are pregnant or breastfeeding, consult your healthcare provider to discuss safer alternatives.

4. Alcohol: Consuming alcohol while taking Gliclazide can increase the risk of hypoglycemia. Limit alcohol intake and monitor blood glucose levels carefully.

Interactions with Other Medications

Gliclazide SR 60 mg can interact with several other medications, which may affect how it works or increase the risk of side effects. These include:

• Other antidiabetic medications (e.g., insulin, metformin)
• Blood pressure medications (e.g., ACE inhibitors, beta-blockers)
• Antifungal drugs (e.g., fluconazole)
• Certain antibiotics (e.g., clarithromycin)
• Anticoagulants (e.g., warfarin)

Always inform your doctor about any other medications you are taking, including over-the-counter drugs and supplements.

Conclusion

GLICLAGALZE MR 60 (Gliclazide SR 60 mg) is an effective medication for managing Type 2 diabetes. Its sustained-release formulation helps to maintain stable blood sugar levels, providing both convenience and efficacy in managing the condition. Like all medications, it comes with potential side effects and interactions, so it is crucial to follow the prescribed dosage and consult with a healthcare provider regularly.

Proper management of diabetes requires a holistic approach, including a balanced diet, regular physical activity, and consistent monitoring of blood glucose levels. With the help of GLICLAGALZE MR 60, many individuals with Type 2 diabetes can effectively control their blood sugar and reduce the risk of long-term complications.

Always consult your healthcare provider for personalized advice and guidance regarding your diabetes treatment plan.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

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