Glimepiride (0.5mg) + Metformin SR (500mg): A Powerful Combination for Diabetes Management

Introduction

SEIZMET G 0.5 is a powerful oral antidiabetic medication that combines Glimepiride (0.5mg) and Metformin SR (500mg). This combination is commonly prescribed to manage type 2 diabetes mellitus (T2DM) by effectively controlling blood sugar levels. It works by addressing both insulin resistance and insulin secretion, providing comprehensive glycemic control.

Key Ingredients

1. Glimepiride (0.5mg): A sulfonylurea class medication that stimulates the pancreas to release insulin, thereby lowering blood glucose levels.

2. Metformin SR (500mg): A biguanide class drug that reduces glucose production in the liver and improves insulin sensitivity, helping the body use glucose effectively.

Key Benefits

• Improved Glycemic Control: The combination of Glimepiride and Metformin SR helps achieve optimal blood sugar levels.

• Enhanced Insulin Sensitivity: Metformin SR reduces insulin resistance, making the body more responsive to insulin.

• Reduced Risk of Hypoglycemia: The lower dose of Glimepiride (0.5mg) minimizes the risk of sudden blood sugar drops.

• Sustained Release Formula: Metformin SR provides long-lasting blood sugar control by maintaining steady glucose levels throughout the day.

• Weight Neutrality: Unlike other diabetes medications, SEIZMET G 0.5 is less likely to cause significant weight gain.

How Does It Work?

SEIZMET G 0.5 works through a dual mechanism:

• Glimepiride (0.5mg) stimulates pancreatic beta cells to produce more insulin, thereby increasing glucose uptake in body tissues.

• Metformin SR (500mg) decreases glucose production in the liver and enhances the uptake and utilization of glucose in muscle and fat tissues.

This synergistic action helps in maintaining stable blood sugar levels, preventing spikes and crashes throughout the day.

Directions for Use

• Dosage: The typical dosage is one tablet per day, preferably taken with a meal or as directed by a healthcare provider.

• Administration: Swallow the tablet whole with water; do not crush or chew it.

• Missed Dose: If a dose is missed, take it as soon as possible unless it’s close to the next scheduled dose.

• Overdose: In case of an overdose, seek immediate medical attention as it may cause severe hypoglycemia.

Side Effects

Although SEIZMET G 0.5 is well-tolerated, some patients may experience mild to moderate side effects, such as:

• Hypoglycemia (low blood sugar) – Dizziness, excessive sweating, shakiness.

• Gastrointestinal Issues – Nausea, vomiting, diarrhea, or abdominal discomfort.

• Headache & Fatigue – Common side effects due to blood sugar fluctuations.

• Vitamin B12 Deficiency – Long-term use of Metformin SR may lead to B12 deficiency.

• Allergic Reactions – Rash, itching, or swelling in rare cases.

Precautions & Warnings

• Not Suitable for Type 1 Diabetes: This medication is only for patients with type 2 diabetes mellitus.

• Kidney & Liver Impairment: Should be used with caution in patients with renal or hepatic dysfunction.

• Alcohol Consumption: Avoid excessive alcohol intake as it can lead to lactic acidosis.

• Pregnancy & Breastfeeding: Consult a doctor before using this medication during pregnancy or lactation.

• Drug Interactions: Avoid taking with NSAIDs, corticosteroids, or beta-blockers without medical supervision.

Price & Availability in India

The price of SEIZMET G 0.5 varies depending on the brand and pharmacy location. On average, a strip of 10 tablets costs around ₹80 – ₹150. It is widely available in retail pharmacies and online stores across India.

Conclusion

SEIZMET G 0.5, containing Glimepiride (0.5mg) and Metformin SR (500mg), is a reliable and effective medication for type 2 diabetes management. Its dual-action formula ensures optimal blood sugar control, improved insulin sensitivity, and minimized risk of hypoglycemia. However, it should always be taken under medical supervision to prevent complications and achieve the best therapeutic outcomes.

If you have diabetes, consult your doctor before starting SEIZMET G 0.5 to ensure it is suitable for your health condition.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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