Glimepiride (4mg), Metformin HCI SR (500mg) 

SEIZMET G4 

Glimepiride (4mg), Metformin HCI SR (500mg) 

SEIZMET G4 is a combination medication containing two primary active ingredients: Glimepiride (4 mg) and Metformin Hydrochloride (500 mg). These two drugs are widely used in the management of type 2 diabetes mellitus. SEIZMET G4 offers an effective therapeutic approach for individuals whose blood sugar levels are inadequately controlled by diet, exercise, or single-drug therapy.

In this article, we will cover the uses, dosage, side effects, price, and conclude by summarizing the importance of SEIZMET G4 in diabetes management.

Uses of Glimepiride 4 mg & Metformin Hydrochloride 500 mg

Glimepiride is a sulfonylurea, a class of drugs that helps control blood sugar levels by stimulating the pancreas to release more insulin. Metformin Hydrochloride, on the other hand, is a biguanide that helps control sugar levels by reducing glucose production in the liver, increasing insulin sensitivity, and improving glucose absorption in the muscles.

Together, the combination of Glimepiride and Metformin is used to:

1. Control blood sugar levels: This helps prevent complications associated with diabetes, such as nerve damage, heart disease, kidney problems, and vision impairment.
2. Improve insulin sensitivity: Metformin helps the body respond better to insulin, reducing insulin resistance—a common feature of type 2 diabetes.
3. Support weight management: While Glimepiride stimulates insulin release, Metformin helps in maintaining or even reducing weight, which can be a concern for many diabetes patients.
4. Reduce A1C levels: SEIZMET G4 helps lower glycated hemoglobin (A1C) levels, which is a key marker for long-term blood sugar control.

Dosage and Administration

The dosage of SEIZMET G4 varies depending on the individual’s medical condition, blood sugar levels, and response to treatment. However, general guidelines for its administration include:

• Initial dose: The recommended starting dose for adults is usually one tablet of SEIZMET G4 (Glimepiride 4 mg/Metformin Hydrochloride 500 mg) once daily with a meal, typically breakfast or the first large meal of the day.
• Adjustments: The dose can be adjusted based on blood sugar monitoring results. Any dose change should be done under the supervision of a healthcare provider.
• Maximum dosage: The daily dose should not exceed 8 mg of Glimepiride or 2000 mg of Metformin Hydrochloride.

It is essential to follow your doctor's recommendations and take the medication consistently to maintain proper blood sugar levels.

Side Effects

Like all medications, SEIZMET G4 may cause side effects in some individuals. These effects vary based on the patient’s health condition, adherence to dosage, and interaction with other medications. Below are common and severe side effects associated with Glimepiride and Metformin:

Common Side Effects

• Hypoglycemia (low blood sugar): Symptoms include dizziness, sweating, confusion, and shakiness, often due to excessive Glimepiride-induced insulin release.
• Nausea: Metformin may cause gastrointestinal discomfort, including nausea, diarrhea, and stomach pain.
• Weight gain: Although Metformin helps in weight management, Glimepiride may cause mild weight gain in some patients.
• Headache: Mild headaches are common in some patients during the initial phase of the treatment.

Severe Side Effects

• Lactic acidosis: A rare but potentially life-threatening side effect of Metformin, characterized by muscle pain, weakness, rapid breathing, and unusual tiredness.
• Severe hypoglycemia: Prolonged low blood sugar levels can lead to fainting, seizures, or coma.
• Allergic reactions: Rarely, SEIZMET G4 can cause severe allergic reactions like swelling, itching, or difficulty breathing.

In case of any severe side effects, patients should seek immediate medical attention.

Contraindications

SEIZMET G4 is contraindicated in individuals with certain conditions, including:

• Severe kidney or liver impairment.
• Diabetic ketoacidosis.
• Heart failure or other significant cardiovascular conditions.
• Alcohol abuse: Chronic alcohol consumption increases the risk of lactic acidosis when taking Metformin.

Pregnant or breastfeeding women should consult their healthcare provider before using SEIZMET G4, as the medication can pose risks to the fetus or infant.

Drug Interactions

Several drugs can interact with Glimepiride and Metformin, affecting their efficacy or increasing the risk of side effects. Common drug interactions include:

• ACE inhibitors, beta-blockers, and diuretics: These can affect blood sugar levels.
• Corticosteroids and oral contraceptives: May reduce the effectiveness of SEIZMET G4.
• Alcohol: Increases the risk of lactic acidosis and hypoglycemia.

Always inform your healthcare provider about all medications and supplements you are taking to avoid harmful interactions.

Conclusion

SEIZMET G4, a combination of Glimepiride 4 mg and Metformin Hydrochloride 500 mg, is a highly effective treatment for managing type 2 diabetes. It addresses high blood sugar levels through complementary mechanisms—Glimepiride stimulating insulin production and Metformin enhancing insulin sensitivity and reducing glucose production. While it has several potential side effects, most can be managed with proper dosage, regular monitoring, and appropriate lifestyle adjustments. Patients using SEIZMET G4 must adhere to their healthcare provider’s advice and monitor their blood sugar levels regularly to achieve optimal results. By keeping blood sugar under control, SEIZMET G4 helps reduce the risk of diabetes-related complications, ultimately improving the patient’s quality of life.Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 7877551268, 7849827488 

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