HYDROPROGRESS (Hydroxyprogesterone Injection 250 mg)

May 31, 2023

Introduction

HYDROPROGRESS 250 is an injectable medication that contains Hydroxyprogesterone (250 mg), a synthetic progestogen used to treat various conditions related to hormonal imbalance. This medication plays an essential role in managing reproductive health, especially for women at risk of preterm labor, and those experiencing hormonal disruptions such as luteal phase defects and amenorrhea. It is also used in assisted reproduction protocols and other gynecological treatments.

In this article, we will explore the key uses, benefits, mechanism of action, dosage guidelines, potential side effects, and frequently asked questions regarding HYDROPROGRESS 250.

Key Uses and Benefits of HYDROPROGRESS 250

1. Prevention of Preterm Birth

One of the most important uses of HYDROPROGRESS 250 is in the prevention of preterm birth in women who are at high risk. This condition is particularly relevant for women with a history of spontaneous preterm births.

How It Works:

  • Hydroxyprogesterone, the active ingredient, helps stabilize the pregnancy and prevent the early onset of labor.
  • It works by relaxing the smooth muscle of the uterus, reducing uterine contractions and lowering the risk of preterm birth.

Benefits:

  • Helps extend the duration of pregnancy, allowing more time for fetal development.
  • Reduces the risk of complications associated with premature birth, such as respiratory distress syndrome, low birth weight, and developmental delays.

2. Treatment of Luteal Phase Defects

Hydroxyprogesterone is frequently used in the treatment of luteal phase defects (LPD), a condition where the luteal phase of the menstrual cycle is too short or insufficient to support a pregnancy.

How It Works:

  • Hydroxyprogesterone increases progesterone levels in the body during the luteal phase, which is crucial for maintaining a healthy uterine lining for embryo implantation.
  • This treatment supports early pregnancy and enhances the chances of a successful conception.

Benefits:

  • Improves fertility outcomes in women with luteal phase defects.
  • Supports implantation and helps maintain pregnancy in the early stages.

3. Management of Amenorrhea

HYDROPROGRESS 250 can also be used to treat amenorrhea, a condition in which women experience the absence of menstrual periods due to hormonal imbalances.

How It Works:

Benefits:

  • Restores normal menstrual cycles and helps women regain fertility.
  • Treats conditions like secondary amenorrhea caused by hormonal deficiencies or irregularities.

Mechanism of Action

Hydroxyprogesterone is a synthetic form of progesterone, a naturally occurring hormone that plays a critical role in the menstrual cycle, pregnancy, and embryo implantation.

  • Progesterone Support: Hydroxyprogesterone acts by mimicking the action of progesterone, which is essential for preparing the uterine lining for pregnancy and maintaining early pregnancy.
  • Prevention of Uterine Contractions: It helps relax the muscles of the uterus, preventing premature contractions and reducing the risk of early labor in pregnant women.
  • Regulation of the Menstrual Cycle: By supporting the luteal phase of the menstrual cycle, hydroxyprogesterone assists in regulating hormonal imbalances that affect menstruation and fertility.

How to Use HYDROPROGRESS 250

HYDROPROGRESS 250 is administered as an intramuscular injection and should be administered by a healthcare professional in a clinical or hospital setting. The exact dosage and schedule will vary depending on the condition being treated.

Dosage Guidelines:

  • Prevention of Preterm Birth: Typically administered once a week starting between 16 to 20 weeks of pregnancy, with the last injection administered at 34 weeks of gestation.
  • Luteal Phase Defects: The dosage and frequency will depend on individual circumstances and the advice of the healthcare provider.
  • Amenorrhea: Hydroxyprogesterone may be given in a series of injections, typically over a 10-14 day period to induce menstruation.

It is essential to follow the healthcare provider's recommendations regarding the dosage and administration frequency.

Potential Side Effects of HYDROPROGRESS 250

While HYDROPROGRESS 250 is effective in treating various conditions, like all medications, it may cause side effects. These are typically mild and resolve after the medication is discontinued or adjusted. However, some side effects may require medical attention.

Common Side Effects:

  • Injection site reactions: Pain, swelling, or redness at the injection site.
  • Headache: Some individuals may experience headaches or dizziness.
  • Gastrointestinal discomfort: Bloating, nausea, or abdominal cramps.
  • Mood changes: Hormonal treatments may lead to mood swings or emotional changes.

Serious Side Effects (Rare):

  • Severe allergic reactions: Symptoms like swelling of the face, lips, tongue, or throat, difficulty breathing, or rash.
  • Blood clots: Women using progestins like hydroxyprogesterone may be at a higher risk for blood clots, particularly if they have a history of clotting disorders.
  • Liver dysfunction: Symptoms of jaundice, such as yellowing of the skin or eyes, which may indicate liver issues.
  • Vision problems: Blurred vision or sudden loss of vision, which should be addressed immediately by a healthcare provider.

If you experience any of these severe symptoms, contact a healthcare provider immediately.

Frequently Asked Questions (FAQs)

1. How long do I need to continue treatment with HYDROPROGRESS 250?

  • The duration of treatment depends on the condition being treated. For preterm birth prevention, the injections are usually given weekly from 16-20 weeks of pregnancy until 34 weeks. For luteal phase defects or amenorrhea, the duration will vary based on individual treatment plans.

2. Can HYDROPROGRESS 250 be used during breastfeeding?

  • It is essential to consult with your healthcare provider before using HYDROPROGRESS 250 while breastfeeding. Though Hydroxyprogesterone is considered safe for most women, your healthcare provider will weigh the risks and benefits based on your situation.

3. What should I do if I miss a dose of HYDROPROGRESS 250?

  • If you miss a dose, contact your healthcare provider for guidance. They will advise you on the best course of action to make up for the missed dose and avoid gaps in treatment.

4. Can I take other medications with HYDROPROGRESS 250?

  • It is essential to inform your healthcare provider of any medications you are taking, including over-the-counter drugs and supplements. Some medications may interact with Hydroxyprogesterone and affect its efficacy or safety.

5. Is there a risk of pregnancy while using HYDROPROGRESS 250?

  • If you are not pregnant and using HYDROPROGRESS 250 for fertility-related issues or hormone regulation, pregnancy may be a possible outcome, especially if the medication is used to treat luteal phase defects or amenorrhea. It’s essential to monitor your cycle and consult your healthcare provider about contraception options if pregnancy is not desired.

Conclusion

HYDROPROGRESS 250 is a vital medication for managing various reproductive health conditions, including preventing preterm birth, treating luteal phase defects, and regulating menstrual cycles. The active ingredient, Hydroxyprogesterone, mimics the natural progesterone hormone in the body, providing critical support during pregnancy and fertility treatments. 

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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