Hydroxyzine Hydrochloride 25 mg

Aug 02, 2022

Introduction

Hydroxyzine Hydrochloride Tablets IP (25mg), commonly marketed as Hydroxyzine, are a well-known medication primarily used for their antihistaminic, anxiolytic, and sedative properties. Hydroxyzine is frequently prescribed for a variety of conditions, including anxiety, sleep disturbances, allergic reactions, and nausea. As part of a class of drugs known as antihistamines, it works by blocking the action of histamine, a substance produced in the body during allergic reactions. Hydroxyzine also has calming and anti-anxiety effects, making it a popular choice for patients dealing with mental health concerns or sleep-related issues.

This article will delve into the uses, benefits, key features, ingredients, recommended dosage, potential side effects, and frequently asked questions (FAQ) about Hydroxyzine Hydrochloride Tablets IP (25mg).

What is Hydroxyzine Hydrochloride?

Hydroxyzine is an antihistamine that works by blocking histamine receptors, particularly the H1 receptors, in the body. This action helps to relieve symptoms caused by allergies such as itching, rashes, and sneezing. Hydroxyzine is available in various forms, including tablets, syrups, and injections, with the 25mg tablet being a common prescription.

The primary role of Hydroxyzine Hydrochloride Tablets IP (25mg) is to treat the following conditions:

  1. Anxiety: Hydroxyzine can provide short-term relief from anxiety by acting on the brain’s neurotransmitter systems. It doesn’t cause the dependency issues commonly associated with other anti-anxiety medications, making it a popular choice for people who need quick relief but do not want to become dependent on medications like benzodiazepines.

  2. Allergic Reactions: Hydroxyzine is effective in managing symptoms of allergic reactions, such as hives, rashes, and itching.

  3. Insomnia: Due to its sedative properties, Hydroxyzine is sometimes prescribed as a short-term solution for people suffering from sleep disturbances or insomnia.

  4. Nausea and Vomiting: It can be used to prevent or treat nausea and vomiting, especially when it is caused by anxiety, motion sickness, or as a side effect of other medications.

  5. Relaxation for Pre-Surgical Anxiety: Hydroxyzine is also commonly given to patients prior to surgery or medical procedures to reduce anxiety and induce a sense of calm.

Key Features of Hydroxyzine Hydrochloride Tablets IP (25mg)

  1. Effective Antihistamine Action
    Hydroxyzine works by blocking the action of histamine, a substance released by the body during allergic reactions. By doing so, it helps reduce symptoms such as itching, sneezing, and runny nose caused by seasonal allergies or other allergic conditions.

  2. Anxiolytic and Sedative Effects
    Hydroxyzine is not only an antihistamine but also has calming effects on the central nervous system, making it useful for patients suffering from anxiety. Its sedative properties make it effective in treating sleep disorders, particularly in patients who have difficulty falling asleep due to stress or anxiety.

  3. Non-Habit Forming
    Unlike other medications for anxiety, Hydroxyzine does not lead to dependency or tolerance, making it a safe option for short-term use. Patients can use it as a quick solution for anxiety or sleep without worrying about addiction.

  4. Short-Term Relief
    Hydroxyzine provides fast-acting relief. Its onset of action is usually within 30 minutes to an hour, making it ideal for individuals needing immediate symptom relief from conditions like anxiety, nausea, or insomnia.

  5. Multiple Uses
    Hydroxyzine is versatile and can be used to treat several conditions, including allergies, anxiety, insomnia, and nausea, as well as being used as a mild muscle relaxant or sedative in pre-surgical settings.

Ingredients of Hydroxyzine Hydrochloride Tablets IP (25mg)

The active ingredient in Hydroxyzine Hydrochloride Tablets IP (25mg) is Hydroxyzine Hydrochloride, which is an antihistamine that also has sedative and anxiolytic properties. Along with this active ingredient, the tablet may contain several inactive ingredients (excipients), which may vary depending on the manufacturer. Common excipients include:

  1. Lactose Monohydrate: Often used as a filler in tablet formulations, lactose helps to give the tablet its shape and size.

  2. Microcrystalline Cellulose: A binder that helps hold the ingredients of the tablet together.

  3. Magnesium Stearate: A lubricant used in the tablet manufacturing process to prevent sticking to the equipment.

  4. Starch: A binder and disintegrant, starch helps the tablet to dissolve in the digestive tract.

  5. Silica Gel: Used as a stabilizer or anti-caking agent to ensure that the tablet remains stable and free from moisture.

These excipients help the tablet maintain its integrity and ensure the proper release of the active ingredient in the body.

How Hydroxyzine Hydrochloride Tablets IP (25mg) Work

Hydroxyzine works by blocking the effects of histamine, a natural substance that plays a major role in allergic reactions. In addition to its antihistamine action, Hydroxyzine also affects the central nervous system by interacting with certain neurotransmitters, producing a calming effect. This dual action of blocking histamine and reducing anxiety makes Hydroxyzine effective in treating conditions like allergies, sleep disturbances, and anxiety.

Usage and Dosage of Hydroxyzine Hydrochloride Tablets IP (25mg)

Hydroxyzine Hydrochloride Tablets IP (25mg) should always be taken according to the guidance of a healthcare professional. The dosage can vary based on the individual’s condition, age, and medical history.

  1. For Anxiety and Tension
    The typical dose for adults is 25mg to 100mg per day, which can be divided into two or three doses depending on the doctor's recommendation.

  2. For Insomnia
    A single dose of 25mg is typically taken 30 minutes to an hour before bedtime to help induce sleep.

  3. For Allergies
    For mild to moderate allergic reactions, a dose of 25mg may be taken up to four times daily, depending on the severity of symptoms.

  4. For Nausea and Vomiting
    Hydroxyzine is also used for nausea and vomiting, with a recommended dose of 25mg taken every 4 to 6 hours as needed.

  5. For Children
    The use of Hydroxyzine in children is typically not recommended without a doctor’s approval. Dosing for children will depend on their age and weight, and a healthcare professional will determine the appropriate dose.

Note: Always follow the prescribed dosage, and avoid exceeding the recommended dose. If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose. Never double the dose to make up for a missed one.

Potential Side Effects of Hydroxyzine Hydrochloride Tablets IP (25mg)

Like any medication, Hydroxyzine may cause side effects in some individuals. However, many people do not experience significant issues. Common side effects include:

  1. Drowsiness: One of the most common side effects of Hydroxyzine is drowsiness. This is why it is often used for treating insomnia. It can also make daytime activities difficult if taken in excess.

  2. Dry Mouth: Some people may experience a dry mouth while using Hydroxyzine.

  3. Dizziness: In some cases, patients may feel lightheaded or dizzy, particularly when standing up quickly.

  4. Headache: Mild headaches may occur as a side effect of Hydroxyzine.

  5. Nausea: Although Hydroxyzine is used to treat nausea, some individuals may experience mild stomach upset.

Less common, but more serious side effects can include confusion, blurred vision, and difficulty urinating. If any severe side effects occur, seek immediate medical attention.

Frequently Asked Questions (FAQ) about Hydroxyzine Hydrochloride Tablets IP (25mg)

1. What is Hydroxyzine used for?
Hydroxyzine is commonly used to treat anxiety, allergic reactions, nausea, insomnia, and as a sedative before surgical procedures.

2. Is Hydroxyzine addictive?
No, Hydroxyzine is not considered addictive, making it a safer option for short-term relief of anxiety or insomnia compared to other sedatives or anti-anxiety medications.

3. How quickly does Hydroxyzine work?
Hydroxyzine typically begins to work within 30 minutes to an hour after administration. Its calming effects can be felt relatively quickly.

4. Can I take Hydroxyzine with other medications?
Hydroxyzine may interact with other medications, including alcohol and sedatives. Always inform your healthcare provider about other medications you are taking to avoid potential drug interactions.

5. Can Hydroxyzine be used in children?
Hydroxyzine can be prescribed for children, but the dosage and suitability should be determined by a pediatrician. It is not typically used in children under the age of 6 months.

Conclusion

Hydroxyzine Hydrochloride Tablets IP (25mg) are a versatile medication used to treat a variety of conditions such as anxiety, allergies, nausea, and insomnia. With its quick onset of action and minimal risk of dependence, it offers an effective solution for patients needing short-term relief from these issues. As with all medications, it’s essential to use Hydroxyzine as directed by a healthcare professional and to be aware of potential side effects. If you're considering Hydroxyzine as part of your treatment plan, make sure to consult your doctor to ensure it’s the right choice for your specific needs. 

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

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