INH IPRATROP DUO :Uses, Side effects, Interactions, Pictures,and more information..

Jul 05, 2024

INH IPRATROP DUO

Ipratropium Bromide20 mcg + Levo-Salbutamol 50 mcg

INH IPRATROP DUO is a combination medication that contains Ipratropium Bromide (20 mcg) and Levo-Salbutamol (50 mcg). This combination is commonly used to manage respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. It offers a synergistic effect, combining the bronchodilatory properties of both drugs to provide relief from bronchospasm and improve airflow in the lungs. This article will delve into the uses, mechanism of action, dosage, side effects, and other important considerations of INH IPRATROP DUO.

Uses of INH IPRATROP DUO

INH IPRATROP DUO is primarily prescribed for:

  1. Chronic Obstructive Pulmonary Disease (COPD): This combination helps manage symptoms such as wheezing, shortness of breath, and chronic cough associated with COPD.
  2. Asthma: It is also used as a bronchodilator in asthma patients, providing quick relief from acute asthma attacks and preventing exacerbations.
  3. Bronchospasm: The medication is effective in treating and preventing bronchospasm, which can be triggered by exercise, allergens, or irritants.

Mechanism of Action

  1. Ipratropium Bromide: Ipratropium is an anticholinergic agent that works by blocking muscarinic receptors in the airways. As a result, it prevents bronchoconstriction and reduces mucus secretion.

  2. Levo-Salbutamol: Levo-Salbutamol is a beta-2 adrenergic agonist that stimulates beta-2 receptors in the bronchial smooth muscles. This stimulation leads to the activation of adenyl cyclase, increasing cyclic AMP levels and causing bronchodilation. Levo-Salbutamol 50 mcg also helps in reducing airway resistance and facilitating the passage of air through the bronchi.

Dosage and Administration

  • Adults and Children (Above 12 Years): The typical dosage is one inhalation four times a day. The maximum recommended dose is 6 inhalations in 24 hours.
  • Children (6-12 Years): The dosage should be determined by a healthcare provider based on the severity of the condition.
  • Administration: Shake the inhaler well before use. Exhale fully, place the mouthpiece in the mouth, and press down on the inhaler while inhaling deeply and slowly.  Rinse the mouth after use to prevent dryness and irritation.

Side Effects

Common side effects of INH IPRATROP DUO include:

  1. Dry Mouth: This is a common side effect due to the anticholinergic action of Ipratropium Bromide.
  2. Headache: Some patients may experience headaches, which are generally mild and transient.
  3. Tremors: Levo-Salbutamol can cause muscle tremors, especially in higher doses.
  4. Nervousness: Some patients may feel jittery or nervous.
  5. Throat Irritation: Inhalation of the medication can cause throat irritation or cough.

Less Common but Serious Side Effects:

  1. Palpitations and Tachycardia: Rapid heartbeat and palpitations may occur due to the beta-2 agonist effect of Levo-Salbutamol.
  2. Hypokalemia: Levo-Salbutamol can cause a decrease in blood potassium levels, leading to hypokalemia.
  3. Paradoxical Bronchospasm: Rarely, the medication can cause worsening of bronchospasm.

Precautions and Warnings

  1. Pre-existing Medical Conditions: Inform your healthcare provider if you have conditions such as heart disease, hypertension, diabetes, hyperthyroidism, or glaucoma.
  2. Pregnancy and Breastfeeding: The safety of INH IPRATROP DUO during pregnancy and breastfeeding is not well established.
  3. Drug Interactions: INH IPRATROP DUO may interact with other medications, including other bronchodilators, beta-blockers, diuretics, and MAO inhibitors. 
  4. Overuse: Overuse of the inhaler can lead to serious side effects. Do not exceed the recommended dosage.

Storage and Handling

  • Storage: Store at room temperature away from moisture, heat, and direct sunlight. Do not freeze the inhaler.
  • Handling: Keep the inhaler clean and dry. 

Conclusion

 It offers the benefits of both an anticholinergic agent and a beta-2 adrenergic agonist, providing quick and sustained relief from bronchospasm. However, it is essential to use this medication under the guidance of a healthcare provider to avoid potential side effects and drug interactions. By understanding the uses, mechanism of action, dosage, and precautions, patients can effectively manage their respiratory conditions and improve their quality of life. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488  

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