Introduction to GEFISTERIS 250

Mar 15, 2024

GEFISTERIS 250 

Gefitinib (250mg) 

Introduction to GEFISTERIS 250

GEFISTERIS 250, commonly known as Gefitinib 250mg, is a medication used in the treatment of non-small cell lung cancer (NSCLC). It is particularly effective in cancers that exhibit certain types of epidermal growth factor receptor (EGFR) mutations.

How GEFISTERIS 250 Works

  • Targeting EGFR: GEFISTERIS 250 inhibits the tyrosine kinase activity of the EGFR, which is involved in the signaling pathway that leads to cell division.
  • Mutation Specificity: It is most effective in tumors with mutations in the EGFR gene, which can lead to the abnormal growth of cancer cells.

Indications and Usage

  • NSCLC Treatment: Primarily prescribed for patients with advanced non-small cell lung cancer with specific EGFR exon 19 deletions or exon 21 substitution mutations.
  • First-Line Treatment: Often used as a first-line treatment option in patients with these genetic abnormalities.

Administration and Dosage

  • Oral Administration: GEFISTERIS 250 is administered orally, usually as a once-daily 250 mg dose.
  • Continued Therapy: Treatment continues as long as clinical benefit is observed or until unacceptable toxicity occurs.

Side Effects and Management

  • Common Adverse Effects: Diarrhea, rash, acne, dry skin, and decreased appetite.
  • Severe Reactions: Rare but serious side effects include interstitial lung disease, severe hepatic impairment, and gastrointestinal perforation.
  • Management Strategies: Side effects can often be managed with supportive care or dose modifications.

Efficacy and Research

  • Clinical Trials: Studies have shown significant improvement in progression-free survival in patients treated with GEFISTERIS 250 compared to chemotherapy.
  • Ongoing Research: Research continues to determine the full potential of GEFISTERIS 250, including its use in combination therapies and other types of cancers.

Conclusion

GEFISTERIS 250 represents a significant advancement in the targeted therapy of NSCLC, offering hope to patients with specific genetic mutations. With ongoing research and clinical use, its role in cancer treatment continues to evolve, promising improved outcomes for patients battling this challenging disease.  A group of highly skilled pharmaceutical professionals founded a specialist pharmaceutical in February 2018 such as Steris Healthcare Pvt Ltd.Sterispharma is a WHO, GMP, and ISO-certified pharma company based in Navi Mumbai. They provide quality medicines at the best price to customers in India as per the standard parameters of WHO. With a steris online pharmacy, you can buy and get home delivery of medicines at your doorsteps. Our main goal at Steris is to provide a wide range of healthcare goods to meet the various needs of the healthcare sector. Steris is dedicated to satisfying the needs of the healthcare industry, whether it be with regard to specialty treatments, rare disease meds, or necessary pharmaceuticals. Steris healthcare products range covers almost every cadre of requirement in today's Medical scenario, widely prescribed under categories like Cardiology, Asthama, Respiratory, Nasal, Diabetic, Endocrinology, Cadiology, Gastrology, Orthopaedic, Anti-infective/antibiotic, General, Urology, Neurology, Nephrology, Oncology, Gynaecology, Pediatric, Dental & Derma range of Products.

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