Introduction to Sevelamer (400mg / 800mg)

Mar 23, 2024

SAVELINER 400 / 800

Sevelamer (400mg / 800mg)

Introduction to Sevelamer (400mg / 800mg)

Sevelamer, available in 400 mg and 800 mg dosages, marketed as SAVELINER 400 / 800, is a phosphate binder used to control phosphorus levels in the blood of patients undergoing dialysis due to chronic kidney disease (CKD).

  • Usage: Controls phosphorus levels in CKD patients
  • Form: Tablets of 400 mg and 800 mg

How SAVELINER 400 / 800 Works

Sevelamer works by binding to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream, which helps manage phosphorus levels in patients with kidney failure.

  • Mechanism of Action: Binds phosphate in the digestive tract
  • Effect: Reduces blood phosphorus levels

Uses of SAVELINER 400 / 800

The primary use of SAVELINER 400 / 800 is to help manage hyperphosphatemia (high blood phosphate levels) in CKD patients on dialysis.

  • CKD and Dialysis: Essential for managing mineral and bone disorders
  • Cardiovascular Health: Helps reduce the risk of heart disease in CKD patients

Dosage and Administration

The dosage of SAVELINER 400 / 800 is determined based on the patient's serum phosphorus level and individual response to the treatment.

  • Starting Dose: Typically based on current phosphorus levels
  • Adjustments: Dose may be adjusted based on regular blood tests

Side Effects of Sevelamer

While SAVELINER 400 / 800 is beneficial for phosphorus control, it can have side effects, which are mostly gastrointestinal.

  • Common Side Effects: Nausea, vomiting, and gastrointestinal discomfort
  • Serious Side Effects: Intestinal obstruction and severe constipation

Interactions with Other Medications

Sevelamer can interact with other medications, especially those that can be bound by it, potentially reducing their effectiveness.

  • Notable Interactions: Reduced absorption of certain medications like ciprofloxacin
  • Management: Monitoring and timing adjustments for medication intake

Conclusion

SAVELINER 400 / 800 (Sevelamer) is a critical medication for managing hyperphosphatemia in patients with chronic kidney disease undergoing dialysis. Adherence to prescribed dosages, awareness of potential side effects, and regular monitoring of phosphorus levels are essential for the effective use of this medication. A team of highly skilled professionals in the pharmaceutical field established Steris Healthcare Pvt Ltd in February 2018. Sterispharma is a certified pharmaceutical company by WHO, GMP, and ISO, situated in Navi Mumbai. It is dedicated to delivering high-quality medications at competitive prices to customers across India, adhering to WHO's stringent standards. Through Steris's online pharmacy, customers can conveniently purchase medicines and receive home delivery. Our primary objective at Steris is to offer a comprehensive range of healthcare products to fulfill the diverse requirements of the healthcare industry. Steris is committed to meeting the healthcare sector's demands, whether it's specialized treatments, medications for rare diseases, or essential pharmaceuticals. The range of Steris healthcare products caters to various medical needs, including Cardiology, Asthma, Respiratory, Nasal, Diabetes, Endocrinology, Gastrology, Orthopedics, Anti-infective/antibiotics,

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