LABIGEST100 & Labetalol (100mg) : Uses, Dosage, Potential Side Effects .....

Apr 18, 2024

Introduction to LABIGEST 100

LABIGEST 100 is a powerful and clinically trusted antihypertensive medication that contains Labetalol 100 mg, an alpha- and beta-adrenergic receptor blocker. It is uniquely formulated to control blood pressure without compromising heart rate or fetal health, making it the preferred option for both general hypertension and hypertensive disorders during pregnancy.Steris Healthcare Pvt. Ltd., a WHO-GMP certified pharmaceutical manufacturer, ensures high-quality standards, affordable pricing, and therapeutic safety with every dose of LABIGEST 100.

What is Labetalol 100 mg?

Labetalol 100 mg belongs to a class of drugs called mixed alpha/beta-adrenergic blockers. It works by relaxing blood vessels (alpha-blockade) and reducing heart rate and cardiac output (beta-blockade), thereby effectively lowering high blood pressure without causing reflex tachycardia.

It is prescribed in tablet form and is commonly used under the name tab labetalol 100 mg in both outpatient and inpatient settings.

Key Therapeutic Uses of Labetalol 100 mg Tablet

1. Treatment of Chronic Hypertension

One of the most common labetalol 100 mg tablet uses is in long-term control of essential hypertension. It reduces the risks of stroke, heart attack, and kidney failure associated with uncontrolled blood pressure.

2. Pregnancy-Induced Hypertension (PIH)

A primary application is in managing pregnancy labetalol 100 mg tablet requirements. It is recommended as a first-line treatment for gestational hypertension and preeclampsia, especially in the second and third trimesters.

3. Hypertensive Emergencies

Labetalol 100 mg is used in acute blood pressure crises where rapid control is needed. The oral tablet may follow intravenous administration during stabilization.

4. Postpartum Hypertension

Helps stabilize elevated BP in new mothers, preventing post-delivery complications.

How LABIGEST 100 Works

LABIGEST 100 acts via:

  • Beta-blockade: Reduces cardiac output by lowering heart rate and contractility

  • Alpha-blockade: Dilates peripheral blood vessels, reducing resistance

Together, these actions reduce systemic blood pressure and prevent organ damage due to long-term hypertension.

Why Labetalol 100 mg Is Preferred in Pregnancy

Labetalol 100 mg uses in pregnancy are backed by clinical trials and global guidelines:

  • Does not reduce placental perfusion, ensuring fetal safety

  • Minimal effects on fetal heart rate compared to other antihypertensives

  • Effective in preeclampsia and eclampsia management

  • Safe during breastfeeding in most cases

Dosage & Administration of LABIGEST 100

Standard Adult Dosage:

  • Initial dose: 100 mg twice daily

  • Adjusted based on BP response

  • Maximum: 2400 mg/day in divided doses

Pregnancy Dose Range:

  • Usually 100–200 mg two or three times daily, per obstetrician guidance

Side Effects of Labetalol 100 mg Tablet

Like all medicines, labetalol 100 mg may cause side effects. Common ones include:

  • Fatigue or dizziness

  • Headache

  • Slowed heart rate (bradycardia)

  • Gastrointestinal discomfort

  • Cold extremities

  • Nasal congestion

  • Rare liver enzyme changes

Most side effects are mild and manageable. Always consult your doctor if symptoms persist.

Drug Interactions with Labetalol

Labetalol may interact with:

  • Other antihypertensives (e.g., ACE inhibitors, calcium channel blockers)

  • Beta-agonists (e.g., salbutamol for asthma)

  • Insulin or oral hypoglycemics (may mask hypoglycemia)

  • General anesthetics

  • MAO inhibitors (should be avoided)

Precautions Before Taking LABIGEST 100

Inform your doctor if you:

  • Have asthma or COPD

  • Have a history of bradycardia or heart block

  • Suffer from diabetes (requires sugar monitoring)

  • Are taking multiple antihypertensives

  • Have liver problems

Do not stop the medication suddenly—always taper under medical supervision.

Frequently Asked Questions (FAQs)

Q1. What is LABIGEST 100 used for?

LABIGEST 100 is used to treat high blood pressure in both non-pregnant adults and pregnant women. It is also effective in controlling blood pressure in hypertensive emergencies and preeclampsia.

Q2. How does labetalol 100 mg help in pregnancy?

Labetalol 100 mg uses in pregnancy include treating gestational hypertension and preeclampsia while maintaining blood flow to the placenta and protecting the fetus.

Q3. What are the side effects of LABIGEST 100?

Common side effects include tiredness, slow heart rate, nausea, and dizziness. Most are temporary and mild.

Q4. Can I take labetalol with other blood pressure medications?

Yes, but only under supervision. Combining with other antihypertensives or diuretics requires close monitoring.

Q5. Is labetalol safe after delivery?

Yes. LABIGEST 100 is often continued postpartum in women with persistent hypertension and is usually safe during breastfeeding.

Conclusion

LABIGEST 100, containing labetalol 100 mg, is a premium-quality, dual-action antihypertensive designed for safe and effective control of blood pressure in both men and women—and most importantly, during pregnancy.Its reliable safety profile, broad clinical use, and WHO-GMP certified manufacturing by Steris Healthcare Pvt. Ltd. make it one of the most trusted choices in the management of hypertension across India.

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