LINZOFIELD 600 & Linezolid (600mg) IP : Uses, Benefits, Side Effects and Other Information.

Introduction

LINZOFIELD 600 is a high-strength antibiotic tablet containing Linezolid 600 mg, formulated to treat serious infections caused by gram-positive bacteria, including multidrug-resistant strains like MRSA (Methicillin-resistant Staphylococcus aureus) and VRE (Vancomycin-resistant Enterococci). It belongs to the oxazolidinone class of antibiotics and is often used in hospital or critical care settings.

Linezolid 600 mg Tablet Uses

Linezolid tablets 600 mg are indicated for the treatment of the following bacterial infections:

• Community-acquired and hospital-acquired pneumonia

• Skin and soft tissue infections

• Bloodstream infections

• Infections caused by resistant gram-positive pathogens

• Diabetic foot infections (without osteomyelitis)

• Vancomycin-resistant Enterococcus faecium (VRE) infections

 Tab Linezolid 600 is particularly effective where other antibiotics may fail due to resistance.

Mechanism of Action of Linezolid 600 mg

Linezolid works by:

• Inhibiting bacterial protein synthesis

• Binding to the 23S portion of the 50S ribosomal subunit

• Preventing the formation of the 70S initiation complex, which is essential for bacterial growth

This unique mechanism makes linezolid 600 mg effective against pathogens that are resistant to other antibiotic classes like macrolides, quinolones, and beta-lactams.

Dosage and Administration

Recommended Dosage:

• Adults: 600 mg every 12 hours (or as directed by the physician)

• Duration typically ranges from 10 to 14 days, depending on infection severity

• Take with or without food

• Do not split or crush the tablet

• Adhere strictly to the prescribed duration to prevent resistance

Side Effects of Linezolid 600 mg Tablet

Most patients tolerate linezolid 600 mg tablet well, but some may experience side effects.

Common Side Effects:

• Diarrhea

• Nausea

• Headache

• Vomiting

• Metallic taste

Serious (but rare) Side Effects:

• Myelosuppression (anemia, leukopenia, thrombocytopenia)

• Peripheral and optic neuropathy (especially with long-term use)

• Serotonin syndrome (when used with SSRIs or MAOIs)

• Lactic acidosis

Regular blood count monitoring is recommended during prolonged treatment.

Precautions and Warnings

• Use with caution in patients taking SSRIs, SNRIs, MAO inhibitors, or tricyclic antidepressants

• Monitor CBC weekly during long courses of treatment

• Avoid alcohol and tyramine-rich foods (e.g., aged cheese, soy, fermented products)

• Not recommended in pregnant or lactating women unless essential

• Adjust dose in patients with renal or hepatic impairment

Drug Interactions

• SSRIs/SNRIs/Tricyclics: Risk of serotonin syndrome

• MAO inhibitors: Contraindicated

• Adrenergic/serotonergic agents: Use with caution

• Inform your doctor about all ongoing medications

Storage Instructions

• Store below 25°C, away from heat and moisture

• Keep in original packaging

• Keep out of reach of children

Why Choose LINZOFIELD 600?

• Manufactured by Steris Healthcare, a trusted name in pharmaceuticals

• Compliant with IP standards ensuring high quality

• Effective against multidrug-resistant infections

• Reliable treatment option for serious hospital-acquired infections

• Convenient oral dosage form for outpatient continuation

FAQs – Linezolid 600 mg Uses and Safety

1. What infections can linezolid 600 be used for?

A: It is used for pneumonia, skin infections, MRSA, and VRE-related conditions.

2. Is it safe to take linezolid 600 with antidepressants?

A: Caution is advised. Consult your doctor to manage interactions and risks of serotonin syndrome.

3. Can I take this tablet without food?

A: Yes, tab linezolid 600 can be taken with or without food.

4. Can I stop taking the tablet once I feel better?

A: No, always complete the full prescribed course to avoid resistance.

5. What should I avoid while on Linezolid 600 mg tablets?

A: Avoid alcohol and tyramine-rich foods to prevent blood pressure spikes.

Conclusion

LINZOFIELD 600, containing Linezolid 600 mg, is a potent weapon against resistant bacterial infections, providing doctors and hospitals with a reliable oral option. Its unique mechanism of action and broad spectrum against gram-positive organisms make it a valuable inclusion in antimicrobial therapy, especially for serious or complicated infections.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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