LOSASTRUM AM : Uses, Benefits, Dosage, Price & Side Effects ..

LOSASTRUM AM 

Losartan Potassium & Amlodipine

LOSASTRUM AM is a combination medication that includes Losartan Potassium and Amlodipine. It is commonly prescribed for the management of hypertension (high blood pressure) and certain heart conditions. This comprehensive guide explores its uses, dosage, side effects, price, composition, and more.

Uses:

1. Hypertension Management: LOSASTRUM AM is primarily used to lower blood pressure in patients with hypertension, reducing the risk of heart attacks, strokes, and other cardiovascular complications.
2. Combination Therapy: The combination of Losartan and Amlodipine offers synergistic effects in controlling blood pressure. Losartan works by blocking angiotensin II receptors, while Amlodipine relaxes blood vessels, leading to improved blood flow and lower blood pressure.
3. Heart Conditions: It may also be prescribed for certain heart conditions such as angina (chest pain) or heart failure in patients who require dual therapy with an angiotensin II receptor blocker (ARB) and a calcium channel blocker (CCB).

Dosage:

• Initial Dose: The typical starting dose of LOSASTRUM AM depends on the individual patient's condition and blood pressure levels. It is usually one tablet daily, containing the specified strengths of Losartan Potassium and Amlodipine.
• Titration: Depending on the patient's response and blood pressure control, the dose may be adjusted under medical supervision.
• Administration: It is usually taken orally with water, with or without food, as directed by the healthcare provider.

Side Effects:

While generally well-tolerated, LOSASTRUM AM may cause some side effects, including:

• Dizziness: This is a common side effect, especially when starting the medication or changing doses. Patients are advised to avoid sudden movements to minimize dizziness.
• Peripheral Edema: Amlodipine, one of the components of LOSASTRUM AM, may cause swelling in the ankles and feet (peripheral edema) due to its vasodilatory effects.
• Hypotension: Excessive lowering of blood pressure may occur, leading to symptoms like lightheadedness or fainting.
• Other Side Effects: Additional potential side effects may include headache, gastrointestinal disturbances, flushing, and changes in heart rate.

Price and Availability:

The price of LOSASTRUM AM can vary based on factors such as the brand, dosage strength, and the number of tablets per pack. It is generally available at pharmacies with a prescription from a healthcare provider.

Composition:

LOSASTRUM AM contains two active ingredients:

1. Losartan Potassium: It belongs to the class of medications known as angiotensin II receptor blockers (ARBs), which work by blocking the effects of angiotensin II, a hormone that constricts blood vessels. This action helps relax blood vessels and lower blood pressure.
2. Amlodipine: It is a calcium channel blocker (CCB) that relaxes and widens blood vessels, improving blood flow and reducing blood pressure.

Precautions:

• Pregnancy and Lactation: LOSASTRUM AM is not recommended during pregnancy as it may harm the fetus. It should also be used with caution during breastfeeding.
• Renal Impairment: Patients with impaired kidney function may require dose adjustments or closer monitoring while taking LOSASTRUM AM.
• Liver Function: Amlodipine, one of the components of LOSASTRUM AM, may require dose adjustments in patients with liver impairment.

Interactions:

LOSASTRUM AM may interact with other medications, such as:

• Potassium Supplements: Concurrent use with potassium supplements or potassium-sparing diuretics may lead to hyperkalemia.
• NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the effectiveness of Losartan in lowering blood pressure.
• CYP3A4 Inhibitors: Some medications that inhibit the enzyme CYP3A4 may increase the levels of Amlodipine in the body, necessitating dose adjustments.

Conclusion:

LOSASTRUM AM, combining Losartan Potassium and Amlodipine, is an effective combination therapy for the management of hypertension and certain heart conditions. Its dual mechanism of action helps lower blood pressure and improve cardiovascular outcomes. However, cautious use, adherence to prescribed doses, and regular monitoring for side effects and interactions are essential for optimal safety and effectiveness. Patients should consult their healthcare providers for personalized guidance and management. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. gynecology, Pediatrics, Dental care, and Dermatology.The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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