LOSASTRUM H : Uses, Benefits, Dosage, Price & Side Effects ..

May 08, 2024

LOSASTRUM H 

Losartan (50mg), Hydrochlorothiazide (12.5mg)

LOSASTRUM H is a combination medication that contains Losartan at a strength of 50mg and Hydrochlorothiazide at 12.5mg. This combination is commonly prescribed to manage hypertension (high blood pressure) in patients who require both an angiotensin II receptor blocker (ARB) and a diuretic.

Uses:

  1. Hypertension Management: LOSASTRUM H is primarily used to lower blood pressure in patients with hypertension, reducing the risk of heart attacks, strokes, and other cardiovascular complications.
  2. Edema Treatment: The Hydrochlorothiazide component in LOSASTRUM H acts as a diuretic, promoting urine production and reducing excess fluid in the body, which can be beneficial in managing edema associated with heart failure or other conditions.
  3. Combination Therapy: The combination of Losartan and Hydrochlorothiazide offers complementary mechanisms of action, providing more comprehensive blood pressure control.

Dosage:

  • Initial Dose: The typical starting dose of LOSASTRUM H is one tablet containing Losartan 50mg and Hydrochlorothiazide 12.5mg once daily.
  • Titration: Depending on the patient's response and blood pressure control, the dose may be adjusted under medical supervision.
  • Administration: It is usually taken orally with water, with or without food.

Side Effects:

While generally well-tolerated, LOSASTRUM H may cause some side effects, including:

  • Dizziness: This is a common side effect, especially when starting the medication or standing up quickly. It typically improves with time.
  • Hypotension: Excessive lowering of blood pressure may occur, leading to symptoms like lightheadedness or fainting.
  • Electrolyte Imbalance: Hydrochlorothiazide can cause electrolyte imbalances, particularly low potassium levels (hypokalemia) or high calcium levels (hypercalcemia).
  • Other Side Effects: Additional potential side effects may include headache, gastrointestinal disturbances, increased urination, and changes in blood sugar levels.

Price and Availability:

The price of LOSASTRUM H can vary based on factors such as the brand, dosage strength, and the number of tablets per pack. It is generally available at pharmacies with a prescription from a healthcare provider.

Composition:

Each LOSASTRUM H tablet contains Losartan Potassium (50mg) and Hydrochlorothiazide (12.5mg) as the active ingredients. Losartan belongs to the class of medications known as angiotensin II receptor blockers (ARBs), while Hydrochlorothiazide is a thiazide diuretic. Together, they work to lower blood pressure and reduce fluid retention.

Precautions:

  • Pregnancy and Lactation: LOSASTRUM H should not be used during pregnancy as it may harm the fetus. It should also be used with caution during breastfeeding.
  • Renal Impairment: Patients with impaired kidney function may require dose adjustments or closer monitoring while taking LOSASTRUM H.
  • Electrolyte Monitoring: Regular monitoring of electrolyte levels, particularly potassium, is recommended during treatment with Hydrochlorothiazide.

Interactions:

LOSASTRUM H may interact with other medications, such as:

  • Potassium Supplements: Concurrent use with potassium supplements or potassium-sparing diuretics may lead to hyperkalemia.
  • NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the effectiveness of Losartan in lowering blood pressure.
  • Other Antihypertensive Agents: Combining LOSASTRUM H with other antihypertensive medications may increase the risk of hypotension.

Conclusion:

LOSASTRUM H, combining Losartan 50mg and Hydrochlorothiazide 12.5mg, is an effective combination therapy for the management of hypertension and edema. Its dual action on blood pressure and fluid retention provides comprehensive treatment. However, cautious use, adherence to prescribed doses, and regular monitoring for side effects and interactions are essential for optimal safety and effectiveness. Patients should consult their healthcare providers for personalized guidance and management. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. gynecology, Pediatrics, Dental care, and Dermatology.The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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