Mesalazine (1g) g
Feb 05, 2024
Mesalazine (1g)
MESALMILE
Mesalazine, also known as mesalamine, is a medication used to treat various inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease. Here's some information about mesalazine:
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Mechanism of Action: Mesalazine works locally in the colon and rectum, where it exerts its anti-inflammatory effects. While the exact mechanism of action is not fully understood, mesalazine is believed to inhibit the production of inflammatory mediators, including prostaglandins and leukotrienes. It may also scavenge free radicals and stabilize lysosomal membranes, further reducing inflammation in the gastrointestinal tract.
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Indications: Mesalazine is indicated for the induction and maintenance of remission in patients with mild to moderate ulcerative colitis and for the maintenance of remission in Crohn's disease involving the colon and/or ileum.
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