MESALMILE: Understanding Mesalazine (1g / 2g)

MESALMILE

Mesalazine (1g / 2g)

MESALMILE: Understanding Mesalazine (1g / 2g)

Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is a medication primarily used to treat inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease. Marketed under various brand names including MESALMILE, it is available in two strengths: 1g and 2g. Here's an in-depth look at this medication, its uses, dosages, and considerations:

Introduction to Mesalazine

Mesalazine, a derivative of salicylic acid, exerts its therapeutic effects locally within the gastrointestinal tract.
It is classified as an aminosalicylate anti-inflammatory drug, acting topically on the mucosal lining of the bowel to reduce inflammation.
Indications

Treatment of mild to moderate ulcerative colitis
Maintenance of remission in ulcerative colitis
Treatment of mild to moderate Crohn's disease
Dosage Strengths

MESALMILE is available in 1g and 2g formulations.
Dosage strength depends on the severity of the condition and individual patient response.

1g Mesalazine

Typically used for mild to moderate cases.
May be prescribed for maintenance therapy after induction of remission.
Dosage forms include tablets, capsules, or granules.

2g Mesalazine

Prescribed for moderate to severe cases or as an initial treatment for acute flares.
May offer a higher dosage for quicker control of inflammation.
Usually administered in divided doses throughout the day.
Administration

Should be taken orally with or after meals.
Tablets or capsules should be swallowed whole and not chewed or crushed.
Granules should be mixed with water before consumption.

Mesalazine should be used with caution in patients with renal impairment.
Regular monitoring of renal function and blood counts may be necessary.
Patients with known hypersensitivity to salicylates should avoid mesalazine.
Drug Interactions

Mesalazine may interact with certain medications such as azathioprine, 6-mercaptopurine, and warfarin.
Close monitoring and possible dosage adjustments may be required when used concomitantly.
Pregnancy and Lactation

The safety of mesalazine during pregnancy and lactation is not fully established.
Benefits versus risks should be carefully evaluated before use in pregnant or breastfeeding women.
Conclusion
MESALMILE, available in 1g and 2g strengths, is a valuable medication in the management of inflammatory bowel diseases. Its localized anti-inflammatory action makes it effective in inducing and maintaining remission in ulcerative colitis and Crohn's disease. However, like all medications, it carries potential risks and side effects, requiring careful consideration and monitoring during use. Patients should follow their healthcare provider's instructions closely and report any adverse effects promptly for appropriate management.  A group of highly skilled pharmaceutical professionals founded a specialist pharmaceutical in February 2018 such as Steris Healthcare Pvt Ltd.Sterispharma is a WHO, GMP, and ISO-certified pharma company based in Navi Mumbai. They provide quality medicines at the best price to customers in India as per the standard parameters of WHO. With a steris online pharmacy, you can buy and get home delivery of medicines at your doorsteps. Our main goal at Steris is to provide a wide range of healthcare goods to meet the various needs of the healthcare sector. Steris is dedicated to satisfying the needs of the healthcare industry, whether it be with regard to specialty treatments, rare disease meds, or necessary pharmaceuticals. Steris healthcare products range covers almost every cadre of requirement in today's Medical scenario, widely prescribed under categories like Cardiology, Asthama, Respiratory, Nasal, Diabetic, Endocrinology, Cadiology, Gastrology, Orthopaedic, Anti-infective/antibiotic, General, Urology, Neurology, Nephrology, Oncology, Gynaecology, Pediatric, Dental & Derma range of Products.

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