Methimazole 10 mg–Trusted Anti-Thyroid Medicine by Steris Healthcare

Introduction

METHIMZOLE 10 is an anti-thyroid medicine that contains Methimazole 10 mg, used to manage hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. Methimazole helps restore hormonal balance by reducing the excessive production of thyroid hormones (T3 and T4). It is frequently prescribed for conditions like Graves’ disease or to prepare patients for thyroid surgery or radioactive iodine therapy.

Manufactured by Steris Healthcare Pvt Ltd, METHIMZOLE 10 offers a reliable and affordable option for long-term thyroid control with consistent therapeutic outcomes.

Methimazole 10 mg Uses

METHIMZOLE 10 is used in the treatment of:

• Hyperthyroidism (Overactive Thyroid Gland)

• Graves’ Disease (Autoimmune hyperthyroidism)

• Pre-operative preparation before thyroidectomy (thyroid surgery)

• Before or after radioactive iodine therapy

It is not recommended for treating hypothyroidism or thyroid nodules without hyperfunction.

Methimazole Mechanism of Action

Methimazole works by inhibiting the enzyme thyroid peroxidase, which is essential for the iodination and coupling of tyrosine residues in thyroglobulin. This process blocks the synthesis of thyroid hormones (T3 and T4), thereby helping to reduce the circulating levels of these hormones in the blood.

How to Use Methimazole 10 mg Tablets (METHIMZOLE 10)

• Take with or without food, but be consistent with timing.

• Swallow the tablet whole with water.

• Monitor thyroid function regularly during treatment.

• Do not stop the medicine abruptly without consulting your doctor.

• Take missed doses as soon as you remember—skip if close to the next dose.

Monitoring Parameters During Therapy

• TSH, Free T3, Free T4 – every 4 to 6 weeks during initiation

• Liver function tests (LFTs) – baseline and periodically

• Complete Blood Count (CBC) – especially during the first 2 months

• Monitor for clinical signs of infection, jaundice, or fatigue

Patient Counseling Points

• Report fever, sore throat, fatigue, or rash immediately.

• Avoid crowded places or sick contacts if your WBC count is low.

• Inform your doctor about pregnancy or planning to conceive.

• Do not use iodine supplements unless advised, as they interfere with treatment.

• Follow a consistent medication schedule to ensure hormone stability.

Methimazole 10 mg During Pregnancy & Lactation

• First Trimester: Avoid due to risk of congenital defects. Use Propylthiouracil (PTU) instead.

• Second and Third Trimesters: Methimazole may be reintroduced under supervision.

• Lactation: Low doses may be used cautiously while breastfeeding, with infant thyroid monitoring.

Storage Instructions

• Store below 25°C, in a dry place away from sunlight.

• Keep out of reach of children.

• Do not use after the expiry date mentioned on the pack.

Methimazole 10 mg Dosage for Adults

The dosage of Methimazole varies based on the severity of hyperthyroidism, age, and response to treatment.

Typical Methimazole Dosage for Adults:

• Initial dose: 10–30 mg per day, divided into 2–3 doses

• Maintenance dose: 5–15 mg per day, based on thyroid hormone levels

Note: Always follow your doctor’s prescription. Thyroid function tests (TSH, T3, T4) are routinely monitored to adjust the dose.

Side Effects of Methimazole 10 mg Tablets

Common Side Effects:

• Rash or itching

• Nausea

• Headache

• Joint pain

• Abdominal pain

• Taste changes

Serious Side Effects (Require Immediate Attention):

• Agranulocytosis (low white blood cell count) – signs include fever, sore throat, infections

• Liver toxicity or hepatitis

• Vasculitis (inflammation of blood vessels)

• Lupus-like syndrome

Methimazole 10 mg Side Effects – Summary

While Methimazole 10 mg is generally well tolerated, patients must be monitored regularly through blood counts and liver function tests.

Precautions Before Using Methimazole Tablets

• Avoid use if allergic to Methimazole or similar anti-thyroid agents

• Regular CBC and liver function monitoring is essential

• Inform your doctor if you are pregnant or planning pregnancy

• Do not use in the first trimester of pregnancy; Propylthiouracil (PTU) is preferred

• Use with caution in patients with existing liver disorders or bone marrow suppression

Drug Interactions – What Drugs Interact with Methimazole?

Methimazole may interact with the following:

• Blood thinners (Warfarin) – may enhance anticoagulant effect

• Beta-blockers (e.g., propranolol) – used adjunctively in hyperthyroidism

• Theophylline or Digoxin – thyroid levels may alter their metabolism

• Radioactive iodine therapy – Methimazole should be paused before administration

• Live vaccines – should be avoided during Methimazole therapy

Always disclose all medications, supplements, and herbal products to your doctor.

Why Choose METHIMZOLE 10 from Steris Healthcare Pvt Ltd?

• Manufactured under WHO-GMP & ISO-certified facilities

• High-quality Methimazole 10 mg formulation for consistent efficacy

• Packaged in pharma-grade blister packs for safety and stability

• Widely prescribed by endocrinologists across India

• Affordable pricing and nationwide availability

Frequently Asked Questions (FAQs)

Q1. What is Methimazole 10 mg used for?

It is used to treat hyperthyroidism, including Graves’ disease, and to prepare patients for thyroid surgery or radioactive iodine therapy.

Q2. How long should I take Methimazole 10 mg?

Treatment usually continues for 12–18 months, depending on response. Your doctor will guide duration based on thyroid function tests.

Q3. Can Methimazole be used in pregnancy?

Methimazole is not recommended in the first trimester due to risk of birth defects. It may be used cautiously in later trimesters under medical supervision.

Q4. What are serious side effects of Methimazole?

Serious side effects include agranulocytosis, liver damage, and vasculitis. Immediate medical help is needed if fever or sore throat occurs.

Q5. Can I stop taking Methimazole suddenly?

No. Abrupt discontinuation can lead to a thyroid storm, a life-threatening condition. Always follow your doctor’s instructions.

Conclusion

METHIMZOLE 10 by Steris Healthcare Pvt Ltd offers a trusted and clinically effective solution for managing hyperthyroidism. With its potent formulation of Methimazole 10 mg, regular monitoring, and physician-guided dosage adjustments, patients can achieve significant control over excessive thyroid hormone levels. Early diagnosis and compliance with treatment play a crucial role in long-term outcomes.