Methimazole 10mg – A Safe and Effective Option for Hyperthyroid Patients

Introduction

METHIMZOLE 10 is a widely used medication containing Methimazole (10mg), primarily prescribed for the treatment of hyperthyroidism. It is an antithyroid drug that plays a crucial role in managing Graves' disease and other conditions related to overactive thyroid glands. By inhibiting thyroid hormone synthesis, METHIMZOLE 10 helps in controlling symptoms such as weight loss, rapid heartbeat, excessive sweating, and nervousness.

Key Ingredients

The active ingredient in METHIMZOLE 10 is Methimazole (10mg), a thiourea derivative that effectively reduces the production of thyroid hormones. It works by blocking the enzyme thyroid peroxidase, which is necessary for hormone synthesis.

Uses of METHIMZOLE 10

1. Treatment of Hyperthyroidism

METHIMZOLE 10 is commonly prescribed to reduce excessive thyroid hormone levels and alleviate symptoms of hyperthyroidism.

2. Management of Graves' Disease

This medication is effective in controlling Graves' disease, an autoimmune disorder that leads to an overactive thyroid.

3. Pre-Surgical Preparation

In some cases, METHIMZOLE 10 is used before thyroid surgery to stabilize hormone levels and minimize complications.

4. Preparation for Radioactive Iodine Therapy

It is often prescribed before or after radioactive iodine treatment to prevent a sudden surge in thyroid hormones.

How Does METHIMZOLE 10 Work?

Methimazole (10mg) works by inhibiting the thyroid peroxidase enzyme, which is responsible for the synthesis of thyroxine (T4) and triiodothyronine (T3). By blocking this enzyme, METHIMZOLE 10 reduces the levels of circulating thyroid hormones, helping to maintain a balanced thyroid function.

Dosage and Administration

Recommended Dosage

• The initial dose for adults with mild hyperthyroidism is typically 15mg per day (1.5 tablets of METHIMZOLE 10).

• For moderate hyperthyroidism, the dosage is 30-40mg per day, divided into multiple doses.

• In severe cases, up to 60mg per day may be required.

• Maintenance dose is usually 5-15mg per day.

Administration

• METHIMZOLE 10 should be taken orally with water.

• It can be taken with or without food, but consistency in administration is recommended.

• Dosage adjustments should be made based on thyroid function test results.

Side Effects of METHIMZOLE 10

While METHIMZOLE 10 is effective, it may cause certain side effects, including:

• Common Side Effects:

  • Nausea

  • Vomiting

  • Dizziness

  • Headache

  • Skin rash

• Serious Side Effects:

  • Agranulocytosis (low white blood cell count) – increased risk of infections.

  • Hepatotoxicity (liver damage) – symptoms include yellowing of the skin, dark urine, and fatigue.

  • Joint pain and swelling.

  • Severe allergic reactions (difficulty breathing, swelling of the face, lips, or throat).

Precautions and Warnings

• Pregnancy and Breastfeeding:

  • METHIMZOLE 10 is not recommended during the first trimester of pregnancy as it may cause fetal abnormalities.

  • It can be used in the second and third trimesters under strict medical supervision.

  • Small amounts of Methimazole can pass into breast milk, so caution is advised for breastfeeding mothers.

• Liver Disease:

  • Patients with pre-existing liver conditions should use METHIMZOLE 10 cautiously.

  • Regular liver function tests are recommended during treatment.

• Blood Disorders:

  • Due to the risk of agranulocytosis, any signs of fever, sore throat, or infections should be reported immediately.

Drug Interactions

METHIMZOLE 10 may interact with other medications, including:

• Anticoagulants (Warfarin): Methimazole may increase the risk of bleeding.

• Beta-blockers: Enhanced effects of beta-blockers may occur.

• Theophylline: Increased levels of theophylline in the blood.

• Insulin or Oral Diabetes Medications: May alter blood sugar control.

Price of METHIMZOLE 10 in India

The price of METHIMZOLE 10 varies depending on the manufacturer and location. On average, a strip of 10 tablets costs between ₹50 to ₹150 in India. It is available at pharmacies, online stores, and hospital dispensaries.

Storage and Handling

• Store METHIMZOLE 10 at a temperature below 30°C.

• Keep it away from moisture and direct sunlight.

• Store it in its original packaging to prevent contamination.

• Keep out of reach of children.

Frequently Asked Questions (FAQs)

1. How long does it take for METHIMZOLE 10 to work?

METHIMZOLE 10 typically starts working within 1-2 weeks, but noticeable improvements in symptoms may take 4-8 weeks.

2. Can I stop taking METHIMZOLE 10 abruptly?

No, sudden discontinuation of METHIMZOLE 10 can cause a thyroid storm (severe hyperthyroidism attack). Always follow the doctor’s instructions when stopping the medication.

3. Is METHIMZOLE 10 safe for long-term use?

While METHIMZOLE 10 is safe for short-term therapy, prolonged use may require regular monitoring due to potential liver toxicity and blood disorders.

4. Can I take METHIMZOLE 10 with food?

Yes, METHIMZOLE 10 can be taken with or without food, but it is advisable to take it at the same time every day.

5. What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Conclusion

METHIMZOLE 10 is an essential medication for managing hyperthyroidism and Graves' disease. It effectively reduces excessive thyroid hormone production, bringing relief from symptoms. However, regular monitoring, adherence to prescribed dosage, and awareness of side effects are crucial for safe and effective use. If you experience any adverse effects, seek medical attention promptly. Always consult a healthcare provider before starting or discontinuing METHIMZOLE 10.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

BUY NOW