Metoprolol SR (50 mg) & Amlodipine (5 mg)

Introduction

Metaprolate AM 50 is a combination medication containing Metoprolol Succinate (50mg) and Amlodipine (5mg), formulated for the effective management of hypertension (high blood pressure) and angina (chest pain). This dual-action drug helps regulate blood pressure and improves heart function, reducing the risk of cardiovascular complications such as heart attacks and strokes.

Key Ingredients

1. Metoprolol Succinate (50mg) - A beta-blocker that slows the heart rate, reduces the workload on the heart, and controls blood pressure.

2. Amlodipine (5mg) - A calcium channel blocker that relaxes blood vessels, ensuring smooth blood flow and lowering blood pressure.

How Metaprolate AM 50 Works

Metaprolate AM 50 works through the synergistic action of its two active ingredients:

• Metoprolol Succinate (SR - Sustained Release) selectively blocks beta-1 receptors, reducing heart rate and blood pressure while improving oxygen supply to the heart.

• Amlodipine relaxes and widens blood vessels, reducing the pressure against which the heart pumps, leading to efficient circulation and reduced strain on the heart.

Uses of Metaprolate AM 50

Metaprolate AM 50 is primarily prescribed for:

1. Hypertension (High Blood Pressure) – Lowers blood pressure and reduces the risk of heart diseases.

2. Angina (Chest Pain) – Improves blood flow to the heart and prevents angina episodes.

3. Heart-related Conditions – Helps in managing conditions like heart failure and arrhythmias (irregular heartbeat).

4. Post-Heart Attack Recovery – Reduces the risk of future cardiovascular events after a heart attack.

Dosage & Administration

• The usual recommended dose is one tablet per day, taken orally with water.

• It is best taken at the same time each day, with or without food.

• Do not crush or chew the tablet as it is a sustained-release formulation.

• Dosage adjustments should be made under a doctor’s supervision, based on patient response.

Precautions & Warnings

• Do not stop suddenly – Abrupt discontinuation may cause rebound hypertension or worsen heart conditions.

• Inform your doctor if you have liver or kidney disorders, asthma, diabetes, or thyroid issues.

• Avoid alcohol – It may enhance drowsiness and lower blood pressure excessively.

• Pregnant and breastfeeding women should consult their doctor before use.

Side Effects

While Metaprolate AM 50 is generally well tolerated, some individuals may experience:

1. Dizziness or Lightheadedness – Due to a sudden drop in blood pressure.

2. Fatigue or Weakness – Common with beta-blockers.

3. Swelling in the Ankles or Feet – A known effect of Amlodipine.

4. Slow Heart Rate (Bradycardia) – Due to Metoprolol's action.

5. Headache or Flushing – As blood vessels dilate.

6. Shortness of Breath – Rare but requires medical attention.

7. Gastrointestinal Issues – Such as nausea or constipation.

Drug Interactions

Metaprolate AM 50 may interact with:

• Other antihypertensive drugs – Can cause excessive blood pressure lowering.

• NSAIDs (Ibuprofen, Naproxen) – May reduce the effectiveness of Metaprolol.

• Diabetes medications – Can mask symptoms of low blood sugar.

• Calcium supplements – May impact Amlodipine absorption.

• Grapefruit Juice – Can increase Amlodipine levels, leading to side effects.

Lifestyle & Dietary Recommendations

• Follow a low-sodium diet – Reduces hypertension.

• Exercise regularly – Helps improve heart function.

• Maintain a healthy weight – Reduces cardiovascular risk.

• Manage stress – Avoid excessive stress and practice relaxation techniques.

• Quit smoking and alcohol consumption – To prevent additional cardiovascular burden.

Price & Availability in India

Metaprolate AM 50 is available in strip packs in pharmacies across India. The price may vary based on the brand and manufacturer but typically ranges between ₹80 to ₹150 per strip of 10 tablets.

Conclusion

Metaprolate AM 50 is an effective and widely prescribed medication for hypertension and angina. With a combination of Metoprolol SR and Amlodipine, it offers a comprehensive approach to heart health, ensuring controlled blood pressure and improved circulation. However, it should be used under medical supervision, with proper monitoring of side effects and adherence to a healthy lifestyle for optimal benefits.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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