Midodrine Hydrochloride 5 mg - Extended-Release Formula…..

Introduction

Low blood pressure, especially when standing, can lead to chronic fatigue, dizziness, blurred vision, and even fainting spells—seriously affecting quality of life. For patients with orthostatic hypotension and autonomic nervous system disorders, maintaining a stable blood pressure is critical. MIDORIGHT 5, containing Midodrine Hydrochloride 5 mg, is a clinically approved vasopressor designed to treat such conditions by restoring vascular tone and improving circulation.

Composition

• Active Ingredient: Midodrine Hydrochloride – 5 mg

• Form: Oral Tablet

• Brand Name: MIDORIGHT 5

Therapeutic Indications

MIDORIGHT 5 is primarily used to treat:

• Symptomatic Orthostatic Hypotension (SOH)

• Autonomic Dysfunction & Neurogenic Hypotension

• Dialysis-Associated Hypotension

• Postural Orthostatic Tachycardia Syndrome (POTS) (off-label)

• Chronic Fatigue related to Low Blood Pressure

Mechanism of Action

Midodrine is a prodrug, converted in the body to its active metabolite desglymidodrine, which:

• Stimulates alpha-1 adrenergic receptors

• Causes vasoconstriction of arteries and veins

• Increases systolic and diastolic blood pressure

• Helps maintain upright blood pressure stability without affecting the brain (non-CNS penetrating)

Dosage & Administration

• Avoid dosing after 6 PM to reduce the risk of supine hypertension during sleep.

Side Effects of Midodrine Hydrochloride

Common Side Effects:

• Goosebumps or chills (piloerection)

• Itching or tingling of the scalp

• Increased urge to urinate or urinary retention

• Elevated BP when lying down

• Flushing or warmth in face

Rare but Serious:

• Supine Hypertension

• Slow heart rate (bradycardia)

• Visual disturbances

• Severe urinary retention

• Chest discomfort

Contraindications

Do not use MIDORIGHT 5 if the patient has:

• Supine (lying down) hypertension

• Severe cardiac disease

• Acute renal impairment

• Urinary retention or obstruction

• Overactive thyroid (hyperthyroidism)

• Tumors of the adrenal gland (pheochromocytoma)

• Known allergy to Midodrine

Precautions

• Use with caution in renal disease

• Avoid in pregnancy and lactation unless advised by a physician

• Do not use concurrently with other vasopressors without medical guidance

• Not recommended in children due to insufficient safety data

Midodrine Hydrochloride 5 mg Generic in India

Midodrine is available in India under various generic and branded formulations. MIDORIGHT 5 offers an affordable and high-quality alternative that is:Manufactured in WHO-GMP certified plantsWidely prescribed by neurologists, cardiologists, and nephrologists.

• Manufactured in WHO-GMP certified plants

• Widely prescribed by neurologists, cardiologists, and nephrologists

• Available across hospital pharmacies, clinics, and online platforms

• Trusted for consistent quality and cost-efficiency

Frequently Asked Questions (FAQs)

Q. Can I take MIDORIGHT 5 at night?

No. Taking it at night can increase your risk of supine hypertension. The last dose should be taken at least 4 hours before bedtime.

Q. Is it safe in patients with kidney disease?

Use with caution and only under medical supervision in patients with renal impairment.

Q. How soon does it work?

Blood pressure typically improves within 1 to 2 hours of ingestion, depending on individual response.

Q. Can it be used for chronic fatigue?

Yes, if fatigue is due to low blood pressure, midodrine may be beneficial under clinical evaluation.

Conclusion

MIDORIGHT 5 (Midodrine Hydrochloride 5 mg) is a trusted solution for individuals suffering from chronic low blood pressure and related symptoms. It enhances vascular tone, promotes circulatory balance, and improves daily functionality. With minimal central side effects and proven efficacy, MIDORIGHT 5 stands as a reliable treatment option for orthostatic hypotension and autonomic instability.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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