Mirabegron 25mg & Silodosin 8mg - Effective BPH & OAB Relief | SILODOSIA M 25 KIT

SILODOSIA M 25 KIT 

Combipack of Mirabegron Extended Release 25 mg & Silodosin 8 mg

Introduction

The combination pack of Mirabegron Extended Release 25 mg and Silodosin 8 mg, marketed as SILODOSIA M 25 KIT, is designed to provide comprehensive treatment for patients suffering from benign prostatic hyperplasia (BPH) and overactive bladder (OAB). This dual-action therapy helps manage urinary symptoms more effectively by targeting both bladder function and prostate relaxation.

Uses of SILODOSIA M 25 KIT

• Benign Prostatic Hyperplasia (BPH): Silodosin 8 mg helps alleviate urinary symptoms caused by an enlarged prostate, such as difficulty urinating, weak stream, and frequent urination.
• Overactive Bladder (OAB): Mirabegron 25 mg aids in relaxing the bladder muscles, reducing the urgency and frequency of urination.
• Improved Quality of Life: The combination therapy provides significant relief from urinary symptoms, enhancing the overall quality of life for patients.

Mechanism of Action

• Silodosin: An alpha-1 adrenergic receptor antagonist that relaxes the smooth muscles in the prostate and bladder neck, facilitating easier urination.
• Mirabegron: A beta-3 adrenergic agonist that relaxes the bladder muscle (detrusor muscle), increasing bladder capacity and reducing the urge to urinate frequently.

Dosage and Administration

• Standard Dosage: The typical dosage is one capsule of Silodosin 8 mg and one tablet of Mirabegron Extended Release 25 mg taken once daily.
• How to Take: Take the medication with food to enhance its absorption and effectiveness. Swallow the capsule and tablet whole with water.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not double the dose to catch up.

Side Effects

• Common Side Effects:
  • Dizziness
  • Diarrhea
  • Light-headedness
  • Nasal congestion
  • Retrograde ejaculation (semen enters the bladder instead of being expelled)
  • Dry mouth
  • Headache
• Serious Side Effects:
  • Severe dizziness or fainting
  • Allergic reactions such as rash, itching, swelling, and difficulty breathing
• Precautions: Regular blood tests may be necessary to monitor for any adverse effects, particularly changes in liver function and prostate-specific antigen (PSA) levels.

Interactions

• Medications:
  • Other alpha-blockers: Combining with other alpha-blockers can enhance blood pressure-lowering effects, leading to hypotension.
  • PDE5 inhibitors: Medications like sildenafil, tadalafil, and vardenafil can increase the risk of low blood pressure.
  • CYP3A4 inhibitors: Drugs such as ketoconazole and ritonavir can increase Silodosin levels in the blood, potentially leading to increased side effects.
  • Blood thinners: Dutasteride can interact with medications like warfarin, affecting blood clotting.
• Lifestyle:
  • Avoid alcohol, as it can enhance the dizziness and light-headedness caused by the medication.
  • Be cautious when driving or operating heavy machinery until you know how the medication affects you.

Warnings and Precautions

• Kidney and Liver Function: Use Silodosin with caution in patients with impaired kidney or liver function. Dose adjustments may be necessary.
• Orthostatic Hypotension: Silodosin can cause a sudden drop in blood pressure when standing up. To reduce the risk, rise slowly from a sitting or lying position.
• Pregnancy and Breastfeeding: This medication is not indicated for use in women, particularly during pregnancy and breastfeeding, due to potential harm to a male fetus.
• Eye Surgery: Inform your eye surgeon if you are taking or have taken this medication, as it can affect pupil dilation during cataract surgery (a condition known as Intraoperative Floppy Iris Syndrome).

Benefits of SILODOSIA M 25 KIT

• Effective Symptom Relief: Provides significant relief from the urinary symptoms associated with BPH and OAB.
• Dual Action: Combines the benefits of Silodosin and Mirabegron to target both the prostate and bladder, offering a comprehensive approach to urinary management.
• Long-Term Management: The combination therapy offers both immediate and long-term benefits in managing urinary symptoms.
• Improved Quality of Life: Patients experience fewer interruptions to daily activities due to urinary issues, enhancing their overall quality of life.

Patient Experience

• Ease of Use: Taking the medication with food as part of a daily routine is simple and convenient for most patients.
• Symptom Improvement: Many patients notice a marked improvement in their urinary symptoms within a few weeks of starting treatment.
• Regular Monitoring: Regular check-ups with a healthcare provider ensure the medication is working effectively and safely.

Conclusion

The combination of Silodosin (8mg) and Mirabegron Extended Release (25mg), marketed as SILODOSIA M 25 KIT, is a highly effective therapy for managing benign prostatic hyperplasia (BPH) and overactive bladder (OAB). Its dual mechanism of action provides comprehensive relief from urinary symptoms, improving the quality of life for patients. Adhering to the prescribed dosage, monitoring for side effects, and being aware of potential interactions are crucial for safe and effective treatment. Always consult your healthcare provider for personalized advice and regular check-ups to ensure optimal health outcomes. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. For further information 

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