Naltrexon 50
Jun 19, 2023
Introduction to NALOTREXAT 50
NALOTREXAT 50 is a prescription tablet containing Naltrexone Hydrochloride IP 50 mg, specifically formulated to support patients in their recovery from opioid or alcohol dependence. It is a long-acting opioid receptor antagonist that helps reduce cravings and prevents relapse by blocking the euphoric and sedative effects of opioids and alcohol.
Manufactured under stringent WHO-GMP and ISO-certified conditions by Steris Healthcare Pvt. Ltd, NALOTREXAT 50 is trusted by healthcare providers for evidence-based addiction treatment programs.
Composition
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Active Ingredient: Naltrexone Hydrochloride IP – 50 mg
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Brand Name: NALOTREXAT 50
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Dosage Form: Film-coated tablet
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Route of Administration: Oral
Naltrexone Hydrochloride 50 mg Uses
NALOTREXAT 50 is used for:
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Maintenance treatment of opioid dependence (after detoxification)
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Prevention of relapse in patients recovering from opioid addiction
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Reduction of alcohol cravings in patients with alcohol use disorder (AUD)
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Adjunctive therapy in behavioral rehabilitation programs
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Discouragement of substance use by blocking euphoric effects
How Naltrexone Hydrochloride Works
Naltrexone is a competitive opioid antagonist that binds to mu-opioid receptors in the brain without activating them, thereby blocking the effects of opioid drugs (like heroin or morphine). It also reduces alcohol cravings by modulating reward pathways in the central nervous system.
✅ In Opioid Dependence:
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Prevents the euphoric high from opioids
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Reduces the risk of relapse
✅ In Alcohol Dependence:
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Decreases alcohol craving
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Minimizes the reinforcing effects of alcohol consumption
Key Benefits of NALOTREXAT 50
✔ Reduces relapse rates in addiction recovery
✔ Non-addictive and not a controlled substance
✔ Can be used as long-term maintenance therapy
✔ Enhances the effectiveness of behavioral therapies
✔ Does not cause physical dependence or tolerance
✔ Once-daily oral dosing improves patient compliance
Dosage & Administration
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Standard Dose: One tablet (50 mg) once daily
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Must be started after complete opioid detoxification (minimum 7–10 days opioid-free)
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In alcohol dependence: start once the patient has stopped alcohol for several days
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Treatment duration is typically 3–6 months, may extend up to a year or more depending on individual needs
Important: Do not initiate in patients with current opioid use – risk of precipitated withdrawal
Side Effects of Naltrexone Hydrochloride
Common Side Effects | Rare/Serious Effects |
---|---|
Nausea or upset stomach | Liver enzyme abnormalities |
Headache | Depression or mood changes |
Dizziness | Allergic reactions (rare) |
Insomnia | Injection site reaction (for depot form) |
Precautions and Warnings
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