Naproxen (250mg), Domperidone SR(30mg) : Understanding NAPROXZEN D 250 ....

Naproxen (250mg), Domperidone SR(30mg)

NAPROXZEN D 250 

NAPROXZEN D 250, elucidating its composition, therapeutic indications, dosage regimen, potential side effects, and precautions for optimal patient care.

Composition:

NAPROXZEN D 250 combines two pharmacologically distinct yet complementary active ingredients: Naproxen and Domperidone SR. Naproxen, a nonsteroidal anti-inflammatory drug (NSAID), exerts potent analgesic, anti-inflammatory, and antipyretic properties, primarily by inhibiting cyclooxygenase enzymes involved in prostaglandin synthesis. Domperidone SR, on the other hand, is a dopamine antagonist with prokinetic effects on the gastrointestinal tract, facilitating gastric emptying and alleviating symptoms of nausea and vomiting.

Therapeutic Indications: The synergistic action of Naproxen and Domperidone SR in NAPROXZEN D 250 makes it an invaluable therapeutic option for various conditions. Common indications include:

1. Pain Management: NAPROXZEN D 250 is highly effective in relieving mild to moderate pain associated with musculoskeletal disorders, rheumatoid arthritis, menstrual cramps, and other inflammatory conditions.
2. Gastrointestinal Disorders: The addition of Domperidone SR augments the efficacy of Naproxen in alleviating symptoms of dyspepsia, gastritis, and gastroesophageal reflux disease (GERD), while also mitigating the risk of NSAID-induced gastric irritation.
3. Migraine: NAPROXZEN D 250 is indicated for the acute treatment of migraine headaches, providing rapid pain relief and reducing associated symptoms such as nausea and photophobia.

Dosage Regimen:

The dosage of NAPROXZEN D 250 should be individualized based on the patient's condition, severity of symptoms, and response to therapy. Typically, the recommended dosage for adults is one tablet taken orally twice daily, preferably with meals to minimize gastrointestinal discomfort. It is crucial to adhere to the prescribed dosage and duration of treatment to optimize therapeutic outcomes while minimizing the risk of adverse effects.

Potential Side Effects:

While NAPROXZEN D 250 is generally well-tolerated, it may be associated with certain adverse effects, primarily attributable to the individual components, Naproxen, and Domperidone SR. Common side effects include gastrointestinal disturbances such as dyspepsia, abdominal pain, and nausea, which are usually mild and transient. Rare but serious adverse reactions may include gastrointestinal bleeding, renal impairment, and cardiac arrhythmias, necessitating prompt medical attention if encountered.

Precautions:

Before initiating therapy with NAPROXZEN D 250, healthcare providers should assess the patient's medical history, concomitant medications, and risk factors for adverse events, particularly in individuals with a history of peptic ulcers, cardiovascular disease, renal impairment, or hypersensitivity reactions to NSAIDs. Caution is advised in elderly patients, as they may be more susceptible to adverse effects such as gastrointestinal bleeding and renal toxicity.

In Conclusion:

NAPROXZEN D 250 represents a potent combination therapy for pain management and gastrointestinal disorders, offering the dual benefits of Naproxen's anti-inflammatory properties and Domperidone SR's prokinetic effects. By understanding its composition, therapeutic indications, dosage regimen, potential side effects, and precautions, healthcare providers can effectively navigate the complexities of NAPROXZEN D 250 and optimize patient outcomes while ensuring safety and efficacy.  Steris Healthcare Pvt Ltd, established in February 2018 by seasoned professionals in the pharmaceutical sector, operates under the name Sterispharma. Headquartered in Navi Mumbai, the company is certified by WHO, GMP, and ISO. Sterispharma is dedicated to providing high-quality medications at affordable prices across India, adhering to stringent WHO guidelines. They offer an online pharmacy platform for easy medicine purchases and home delivery. The company's mission is to deliver a diverse range of healthcare products catering to the varied needs of the medical community. From advanced treatments and rare condition medications to essential health supplies, Sterispharma aims to meet the extensive demands of the healthcare industry. Their product range covers numerous health fields, including Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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