OLMISTRUM TRIO : Uses, Side Effects, Dosage & More

OLMISTRUM TRIO

Olmesartan (40mg), Cilnidipine (10mg), Chlorthalidone (12.5mg)

Olmesartan, Cilnidipine, and Chlorthalidone combination, marketed under the brand name OLMISTRUM TRIO, is a potent medication used to manage hypertension (high blood pressure). Each component of this combination plays a crucial role in controlling blood pressure, thereby reducing the risk of cardiovascular diseases such as heart attacks and strokes. This combination is particularly beneficial for patients requiring multiple medications to achieve optimal blood pressure control.

Uses

Olmesartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking the action of certain natural substances that tighten blood vessels.

Cilnidipine is a calcium channel blocker that relaxes and widens blood vessels, making it easier for the heart to pump blood and reducing its workload. It specifically targets the L-type and N-type calcium channels, offering both vascular and neuroprotective benefits.

Chlorthalidone is a thiazide-like diuretic (water pill) that helps prevent the body from absorbing too much salt, which can cause fluid retention. It reduces fluid buildup and lowers blood pressure by helping the kidneys eliminate excess sodium and water from the body.

Dosage

The dosage of OLMISTRUM TRIO is determined by the healthcare provider based on the patient's condition and response to the treatment. The typical starting dose for adults is one tablet once daily, preferably at the same time each day. It is important to follow the prescribed dosage instructions closely to ensure the medication's effectiveness and minimize the risk of side effects.

Side Effects

While OLMISTRUM TRIO is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Headache
• Fatigue
• Swelling in the ankles or feet (edema)
• Increased urination

Less common but more serious side effects may include:

• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Signs of kidney problems (such as change in the amount of urine)
• Signs of high potassium levels (such as muscle weakness, slow or irregular heartbeat)

If any side effects are severe or persistent, it is essential to contact a healthcare provider promptly.

Precautions

Before taking OLMISTRUM TRIO, it is important to inform your healthcare provider about any medical history, especially related to:

• Kidney disease
• Liver disease
• Electrolyte imbalances (such as high potassium or low sodium levels)
• Dehydration
• Heart failure or other heart conditions

Pregnant or breastfeeding women should avoid using this medication, as it can harm the unborn baby or nursing infant. Additionally, patients should inform their doctor about all the medications they are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements, to avoid potential drug interactions.

Interactions

OLMISTRUM TRIO can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. Some notable interactions include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, which can reduce the effectiveness of Olmesartan and increase the risk of kidney damage.
• Potassium supplements or potassium-sparing diuretics, which can increase the risk of hyperkalemia (high potassium levels).
• Other antihypertensive medications, which may enhance the blood pressure-lowering effects and increase the risk of hypotension (low blood pressure).

Conclusion

OLMISTRUM TRIO, combining Olmesartan, Cilnidipine, and Chlorthalidone, offers a comprehensive approach to managing hypertension. By leveraging the complementary mechanisms of action of each component, this medication provides effective blood pressure control and reduces the risk of cardiovascular complications. Patients should adhere to their prescribed dosage and take necessary precautions to ensure the best outcomes. Regular consultations with healthcare providers are essential to monitor the medication's efficacy and make any necessary adjustments. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

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