Pramipexole (0.125mg)-View Uses, Dosage, Side Effects,....

Apr 23, 2024

PRAMIXOLE 0.125 

Pramipexole (0.125mg)

Pramipexole is a medication primarily used to treat Parkinson's disease and restless legs syndrome (RLS). This is a summary of its applications, recommended dosage, and possible adverse effects:

 

Uses:
Parkinson's Disease: Pramipexole is used as a dopamine agonist to help manage the symptoms of Parkinson's disease, such as tremors, stiffness, and difficulty with movement.
Restless Legs Syndrome (RLS): Pramipexole is also approved for the treatment of moderate to severe RLS, a condition characterized by uncomfortable sensations in the legs and an irresistible urge to move them.
 

Dosage:
Parkinson's Disease:
Starting Dose: Typically, the initial dose for Parkinson's disease is around 0.125 mg taken orally three times per day.
Maintenance Dose: The dosage may be gradually increased over time, usually at intervals of 5 to 7 days, based on individual response and tolerability. The maximum recommended daily dose is 4.5 mg.
Restless Legs Syndrome (RLS):
The starting dose for RLS is typically lower, around 0.125 mg taken orally once daily, 2 to 3 hours before bedtime.
Similarly, the dose may be adjusted gradually based on individual response and tolerability, with the maximum recommended daily dose being 0.75 mg.
 

Side Effects:
Common Side Effects: Nausea, dizziness, drowsiness, fatigue, constipation, insomnia, headache.
Less Common Side Effects: Orthostatic hypotension drop in blood pressure upon standing, hallucinations, confusion, impulse control disorders (such as compulsive gambling or eating), dyskinesias (abnormal involuntary movements).
Rare but Serious Side Effects: Some individuals may experience symptoms of augmentation, where RLS symptoms worsen over time with continued use of pramipexole. Additionally, sudden onset of sleep, sometimes without warning, has been reported.
 

Withdrawal Effects: Abrupt discontinuation of pramipexole may lead to withdrawal symptoms such as worsening of RLS symptoms, anxiety, agitation, and sweating.
It's important to take pramipexole exactly as prescribed by a healthcare professional and to report any concerning side effects promptly. Adjustments to the dosage should only be made under medical supervision. Pramipexole may interact with other medications, so it's essential to inform your doctor about all medications and supplements you're currently taking.A team of highly skilled professionals in the pharmaceutical field established Steris Healthcare Pvt Ltd in February 2018. Sterispharma is a certified pharmaceutical company by WHO, GMP, and ISO, situated in Navi Mumbai. It is dedicated to delivering high-quality medications at competitive prices to customers across India, adhering to WHO's stringent standards. Through Steris's online pharmacy, customers can conveniently purchase medicines and receive home delivery. Our primary objective at Steris is to offer a comprehensive range of healthcare products to fulfill the diverse requirements of the healthcare industry. Steris is committed to meeting the healthcare sector's demands, whether it's specialized treatments, medications for rare diseases, or essential pharmaceuticals. The range of Steris healthcare products caters to various medical needs, including Cardiology, Asthma, Respiratory, Nasal, Diabetes, Endocrinology, Gastrology, Orthopedics, Anti-infective/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental, and Dermatology.  For further information: 

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