Prasugrel (10mg) & PERUSUGREL - 10 Mg : View Uses, Dosage, Side Effects...

PERUSUGREL - 10 Mg

Prasugrel (10mg)

Prasugrel 10 mg is a potent antiplatelet medication widely prescribed to prevent blood clots in patients with acute coronary syndrome (ACS) who are undergoing percutaneous coronary intervention (PCI). As a member of the thienopyridine class, PERUSUGREL - 10 acts by inhibiting platelet activation and aggregation, crucial steps in the formation of blood clots. Available in a 10mg dosage, it is marketed under various brand names, including "PERUSUGREL - 10."

Uses

Prasugrel is primarily used to reduce the risk of thrombotic cardiovascular events in patients with ACS, including those experiencing unstable angina, non-ST-elevation myocardial infarction (NSTEMI), or ST-elevation myocardial infarction (STEMI). It is typically prescribed in combination with aspirin to enhance antiplatelet therapy's effectiveness, thereby preventing complications such as heart attacks and strokes following PCI procedures.

Specific Uses

• Prevention of Stent Thrombosis: Following PCI with stent implantation, Prasugrel helps prevent the formation of clots in the stent, ensuring its patency.
• Reduction of Heart Attack Risk: In patients with a history of myocardial infarction, Prasugrel significantly lowers the likelihood of subsequent heart attacks.
• Stroke Prevention: For those with ACS, the medication reduces the risk of ischemic strokes by preventing clot formation in the arteries supplying the brain.

Dosage

The recommended dosage of Prasugrel for adults is typically a 60mg loading dose, followed by a maintenance dose of 10mg once daily. The medication should be taken with or without food, and it is crucial to adhere to the prescribed regimen to ensure optimal efficacy and safety.

Dosage Adjustments

• Elderly Patients: Patients aged 75 years or older are generally prescribed a lower maintenance dose of 5mg daily due to an increased risk of bleeding.
• Renal Impairment: No dosage adjustment is required for patients with renal impairment, but caution is advised.
• Hepatic Impairment: For those with mild to moderate hepatic impairment, no adjustment is necessary. However, Prasugrel is not recommended for patients with severe hepatic impairment due to the potential risk of bleeding.

Side Effects

Like all medications, Prasugrel can cause side effects, ranging from mild to severe. It is important for patients to be aware of these potential reactions and consult their healthcare provider if they experience any adverse effects.

Common Side Effects

• Bleeding: The most common side effect, including nosebleeds, bruising, and gastrointestinal bleeding.
• Hypertension: Some patients may experience increased blood pressure.
• Headache: Mild to moderate headaches can occur, particularly at the start of treatment.

Severe Side Effects

• Major Bleeding: Includes life-threatening bleeding events such as intracranial hemorrhage and significant gastrointestinal bleeding.
• Thrombotic Thrombocytopenic Purpura (TTP): A rare but serious condition characterized by small clots forming throughout the body, leading to low platelet counts and anemia.
• Hypersensitivity Reactions: Severe allergic reactions, including rash, itching, and swelling, particularly of the face and throat.

Precautions

Before starting Prasugrel, patients should inform their healthcare provider about any pre-existing medical conditions, medications, or allergies to ensure safe use.

Key Precautions

• Bleeding Disorders: Patients with active pathological bleeding or a history of bleeding disorders should avoid Prasugrel.
• Surgery: Discontinuation of Prasugrel at least 7 days before any planned surgery is recommended to reduce bleeding risk.
• Liver Dysfunction: Use with caution in patients with mild to moderate liver impairment.
• Pregnancy and Breastfeeding: Prasugrel should only be used during pregnancy if clearly needed, and breastfeeding is not recommended while on this medication.

Interactions

Prasugrel can interact with other medications, potentially altering its effectiveness or increasing the risk of adverse effects.

Drug Interactions

• Anticoagulants and NSAIDs: Concurrent use with other blood thinners like warfarin or nonsteroidal anti-inflammatory drugs (NSAIDs) can significantly increase bleeding risk.
• Proton Pump Inhibitors (PPIs): Some studies suggest that PPIs like omeprazole may reduce the efficacy of Prasugrel, though this interaction remains controversial.

Conclusion

Prasugrel (10mg), marketed as "PERUSUGREL - 10," is an essential medication in the management of acute coronary syndrome, particularly for patients undergoing PCI. Its potent antiplatelet effects help prevent serious cardiovascular events, though it requires careful monitoring and adherence to prescribed dosages to minimize risks, especially related to bleeding. Patients should maintain open communication with their healthcare providers to ensure the safe and effective use of Prasugrel. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology.

For further information: 

 EMAIL:  info@sterispharma.com  / contact@sterispharma.com   

 CALL/WHATSAPP: 7877551268, 7849827488

BUY NOW