Pregabalin and Nortriptyline Tablets Uses in Neuropathic Pain & Fibromyalgia

Introduction

Pregabalin and nortriptyline tablets uses include the treatment of various types of neuropathic pain, which is nerve pain caused by conditions such as diabetes, spinal disorders, shingles, or nerve compression syndromes. Marketed as PREGABRIAL NT, this combination of Pregabalin 75 mg and Nortriptyline 10 mg provides dual-action relief by calming nerve activity and enhancing mood, making it a widely trusted choice in long-term pain management.

Composition

• Pregabalin – 75 mg

• Nortriptyline – 10 mg

• Form – Oral tablet

• Brand Name – PREGABRIAL NT

Pregabalin and Nortriptyline Tablets Uses

The combination is commonly used in the treatment of:

• Diabetic neuropathy

• Postherpetic neuralgia (pain after shingles)

• Sciatica and spinal nerve pain

• Fibromyalgia

• Chronic lower back and neck pain with nerve involvement

• Nerve-related pain after injury or surgery

• Sometimes used off-label in fibromyalgia with anxiety symptoms

This combination provides both pain relief and mood stabilization, especially in chronic pain patients with poor quality of life due to persistent nerve irritation.

How It Works

• Pregabalin: Modulates calcium channels in nerve cells, reducing the release of pain-signaling neurotransmitters.

• Nortriptyline: A tricyclic antidepressant (TCA) that improves nerve pain perception by increasing serotonin and norepinephrine levels.

Together, they reduce nerve pain and improve mood-related symptoms, offering better control in neuropathic pain syndromes.

Dosage and Administration

• Typical dose: One tablet once or twice daily

• Take after food to minimize stomach upset

• Do not stop abruptly—dose should be tapered under medical supervision

Pregabalin Side Effects and Nortriptyline Effects

Common Side Effects

• Dizziness or drowsiness

• Dry mouth

• Blurred vision

• Constipation

• Weight gain

• Fatigue

Serious (but rare) Side Effects

• Mood changes or suicidal thoughts

• Difficulty urinating

• Irregular heartbeat

• Allergic reactions (rash, swelling)

Regular monitoring and dose adjustments help minimize side effects.

Precautions

• Use with caution in elderly patients and those with heart, liver, or kidney issues

• Avoid alcohol and sedatives (may increase drowsiness)

• Not recommended during pregnancy or breastfeeding unless advised

• Do not drive or operate heavy machinery until you know how the medicine affects you

Why Steris is Better Than Other Pharmacies

Steris is known for its GMP-certified manufacturing, regulatory excellence, and high-quality standards. With a focus on safe, effective, and reliable products, Steris has become a trusted name in pharmaceutical care, offering better consistency than many local alternatives.

FAQs – Pregabalin and Nortriptyline Tablets

Q1. What are pregabalin and nortriptyline tablets used for?

They are mainly used for neuropathic pain due to diabetes, shingles, nerve injury, or spinal compression.

Q2. Can PREGABRIAL NT be taken long term?

Yes, it is safe for long-term use under medical supervision with regular monitoring.

Q3. Do these tablets help with anxiety?

Nortriptyline may help reduce anxiety symptoms that often accompany chronic pain.

Q4. Is weight gain common with this medicine?

Yes, weight gain is a possible side effect due to increased appetite or fluid retention.

Conclusion

Pregabalin and nortriptyline tablets offer an effective and well-tolerated solution for managing chronic neuropathic pain. With the combined benefits of nerve pain relief and mood stabilization, PREGABRIAL NT plays a vital role in improving patient comfort and quality of life. When sourced from reliable pharmaceutical companies like Steris, patients and healthcare providers can trust in the product's consistency, safety, and therapeutic value. Always consult a healthcare professional for appropriate dosage and monitoring.