"DISULFREE 500mg: Effective Disulfiram Alcohol Therapy"

Mar 21, 2024

DISULFREE    

Disulfiram (500mg)

Disulfiram (500mg)

Disulfiram is a medication primarily used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). When taken, it inhibits the enzyme acetaldehyde dehydrogenase, leading to a severe reaction when alcohol is consumed.

Mechanism of Action

  • Enzyme Inhibition: Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, causing an accumulation of acetaldehyde in the blood.

  • Deterring Alcohol Consumption: The resulting acetaldehyde accumulation causes unpleasant effects when alcohol is consumed, which deters the individual from drinking.

Uses and Benefits

  • Alcohol Dependence Treatment: Primarily used as part of a comprehensive treatment program for alcohol dependency.

  • Behavioral Modification: Helps in reinforcing the motivation to avoid alcohol by associating its consumption with negative physical reactions.

Dosage and Administration

  • Standard Dosage: Disulfiram is typically administered in a dosage of 500mg daily.

  • Treatment Initiation: Usually started after the patient has abstained from alcohol for some days.

  • Monitoring and Adjustment: Dosage may be adjusted based on the patient's response and any side effects.

Side Effects and Precautions

  • Common Side Effects: May include skin rash, mild headaches, and drowsiness.

  • Severe Reactions: Consuming alcohol while on Disulfiram can lead to severe reactions, including nausea, vomiting, headache, and palpitations.

  • Precautions: Patients should avoid all forms of alcohol, including those found in sauces, vinegars, and some medications.

Disulfiram and Alcohol Interaction

  • Immediate Reaction: Even small amounts of alcohol can produce a very uncomfortable reaction that includes flushing, nausea, and palpitations.

  • Risk of Severe Symptoms: These reactions can be severe and may include difficulty breathing, heart problems, and seizures.

In conclusion, Disulfiram (commonly known as DISULFREE in a 500mg dosage) is a powerful aid in the treatment of alcohol dependence. It acts by discouraging alcohol consumption through the uncomfortable physical reactions it triggers when alcohol is ingested. Proper administration and adherence to medical advice are crucial to maximize the benefits and minimize the risks associated with this medication.  A team of highly skilled professionals in the pharmaceutical field established Steris Healthcare Pvt Ltd in February 2018. Sterispharma is a certified pharmaceutical company by WHO, GMP, and ISO, situated in Navi Mumbai. It is dedicated to delivering high-quality medications at competitive prices to customers across India, adhering to WHO's stringent standards. Through Steris's online pharmacy, customers can conveniently purchase medicines and receive home delivery. Our primary objective at Steris is to offer a comprehensive range of healthcare products to fulfill the diverse requirements of the healthcare industry. Steris is committed to meeting the healthcare sector's demands, whether it's specialized treatments, medications for rare diseases, or essential pharmaceuticals. The range of Steris healthcare products caters to various medical needs, including Cardiology, Asthma, Respiratory, Nasal, Diabetes, Endocrinology, Gastrology, Orthopedics, Anti-infective/antibiotics,

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